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CH476717A - Verfahren zur Herstellung von Halogenribofuranosiden - Google Patents

Verfahren zur Herstellung von Halogenribofuranosiden

Info

Publication number
CH476717A
CH476717A CH761265A CH761265A CH476717A CH 476717 A CH476717 A CH 476717A CH 761265 A CH761265 A CH 761265A CH 761265 A CH761265 A CH 761265A CH 476717 A CH476717 A CH 476717A
Authority
CH
Switzerland
Prior art keywords
halibofuranosides
preparation
Prior art date
Application number
CH761265A
Other languages
English (en)
Inventor
William Holly Frederick
Walton Edward
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH476717A publication Critical patent/CH476717A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/02Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH761265A 1964-06-03 1965-06-01 Verfahren zur Herstellung von Halogenribofuranosiden CH476717A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US372367A US3277077A (en) 1964-06-03 1964-06-03 3-deoxy ribofuranosyl halides
US42915465A 1965-01-29 1965-01-29

Publications (1)

Publication Number Publication Date
CH476717A true CH476717A (de) 1969-08-15

Family

ID=27005738

Family Applications (1)

Application Number Title Priority Date Filing Date
CH761265A CH476717A (de) 1964-06-03 1965-06-01 Verfahren zur Herstellung von Halogenribofuranosiden

Country Status (6)

Country Link
US (1) US3277077A (de)
BR (1) BR6570099D0 (de)
CH (1) CH476717A (de)
DE (1) DE1543203A1 (de)
GB (3) GB1100715A (de)
NL (1) NL6507083A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3346561A (en) * 1965-10-24 1967-10-10 Merck & Co Inc Pyrimidine 3-deoxynucleosides
US3455900A (en) * 1967-05-19 1969-07-15 Upjohn Co Process for selectively preparing lincomycin 7-acylates
US3513155A (en) * 1968-05-07 1970-05-19 Upjohn Co Sulfoxides of 7-halo-7-deoxylincomycins and process
JPS5012246A (de) * 1973-06-01 1975-02-07
US4282349A (en) * 1976-12-13 1981-08-04 Board Of Control Of Michigan Technological University Crystalline ribofuranosyl halides and other derivatives and methods for producing same
US5358936A (en) * 1990-08-03 1994-10-25 Paul Gordon Anionic furanose derivatives, methods of making and using the same
MX9303713A (es) * 1992-06-22 1994-05-31 Lilly Co Eli Proceso estereoselectivo para preparar un derivadoribofuranosilo enriquecido con alfa anomero.
CN103622988B (zh) * 2012-08-23 2016-08-17 北京冠瑞金生物科技有限公司 虫草素在制备抗抑郁症的药物中的用途及其制备而得的快速抗抑郁症药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2719844A (en) * 1952-10-16 1955-10-04 Dimroth Karl Method of producing nucleosides by chemical processing
US2876230A (en) * 1956-11-23 1959-03-03 Merck & Co Inc 1-halomercuri, trihalo benzimidazoles
US2949449A (en) * 1959-01-14 1960-08-16 Hoffmann La Roche Synthesis of 3, 5-diaroyl-2-deoxy-d-ribofuranosyl ureas
US3207750A (en) * 1964-05-29 1965-09-21 Upjohn Co Derivatives of decoyinine

Also Published As

Publication number Publication date
BR6570099D0 (pt) 1973-09-06
GB1100714A (en) 1968-01-24
DE1543203A1 (de) 1970-01-15
GB1100715A (en) 1968-01-24
NL6507083A (de) 1965-12-06
US3277077A (en) 1966-10-04
GB1100713A (en) 1968-01-24

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Legal Events

Date Code Title Description
PL Patent ceased