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CH420142A - Process for the preparation of 3B, 20-diacyloxy-9a, 11B-dichloro-17,20-epoxy-16-methyl-5a-pregnanes - Google Patents

Process for the preparation of 3B, 20-diacyloxy-9a, 11B-dichloro-17,20-epoxy-16-methyl-5a-pregnanes

Info

Publication number
CH420142A
CH420142A CH158865A CH158865A CH420142A CH 420142 A CH420142 A CH 420142A CH 158865 A CH158865 A CH 158865A CH 158865 A CH158865 A CH 158865A CH 420142 A CH420142 A CH 420142A
Authority
CH
Switzerland
Prior art keywords
pregnanes
diacyloxy
dichloro
epoxy
methyl
Prior art date
Application number
CH158865A
Other languages
German (de)
Inventor
Major Evans Ronald
Elks Joseph
Arthur Hems Benjamin
Graham William
Francis Oughton John
Ian Gregory Gordon
Walker Thomas
Selwyn Hunt John
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2489459A external-priority patent/GB956271A/en
Priority claimed from GB2489559A external-priority patent/GB956272A/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CH420142A publication Critical patent/CH420142A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/02Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents specially adapted to protect contents from mechanical damage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH158865A 1959-07-20 1960-07-19 Process for the preparation of 3B, 20-diacyloxy-9a, 11B-dichloro-17,20-epoxy-16-methyl-5a-pregnanes CH420142A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2489459A GB956271A (en) 1959-07-20 1959-07-20 Improvements in or relating to the preparation of steroid compounds
GB2489559A GB956272A (en) 1959-07-20 1959-07-20 Improvements in or relating to the preparation of steroid compounds

Publications (1)

Publication Number Publication Date
CH420142A true CH420142A (en) 1966-09-15

Family

ID=26257367

Family Applications (2)

Application Number Title Priority Date Filing Date
CH158865A CH420142A (en) 1959-07-20 1960-07-19 Process for the preparation of 3B, 20-diacyloxy-9a, 11B-dichloro-17,20-epoxy-16-methyl-5a-pregnanes
CH820560A CH421097A (en) 1959-07-20 1960-07-19 Process for the preparation of 16-methyl steroids

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH820560A CH421097A (en) 1959-07-20 1960-07-19 Process for the preparation of 16-methyl steroids

Country Status (3)

Country Link
BE (1) BE593213A (en)
CH (2) CH420142A (en)
SE (1) SE314066B (en)

Also Published As

Publication number Publication date
CH421097A (en) 1966-09-30
SE314066B (en) 1969-09-01
DE1418857A1 (en) 1968-12-12
BE593213A (en) 1960-11-14

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