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CH387628A - Verfahren zur Herstellung des 3-Oxy-17-Brom-9(11)pregnen-20-ons oder der entsprechenden 17,21-Dibromverbindung und deren 3-Ester - Google Patents

Verfahren zur Herstellung des 3-Oxy-17-Brom-9(11)pregnen-20-ons oder der entsprechenden 17,21-Dibromverbindung und deren 3-Ester

Info

Publication number
CH387628A
CH387628A CH7572959A CH7572959A CH387628A CH 387628 A CH387628 A CH 387628A CH 7572959 A CH7572959 A CH 7572959A CH 7572959 A CH7572959 A CH 7572959A CH 387628 A CH387628 A CH 387628A
Authority
CH
Switzerland
Prior art keywords
pregnen
oxy
bromo
ester
preparation
Prior art date
Application number
CH7572959A
Other languages
English (en)
Inventor
Martin Chemerda John
Allen Cutler Frank
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH387628A publication Critical patent/CH387628A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/872—Nocardia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CH7572959A 1958-07-14 1959-07-14 Verfahren zur Herstellung des 3-Oxy-17-Brom-9(11)pregnen-20-ons oder der entsprechenden 17,21-Dibromverbindung und deren 3-Ester CH387628A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US748178A US3013031A (en) 1958-07-14 1958-07-14 9(11)-16-pregnadiene-20-one compounds through 17 and 21 brominated intermediates

Publications (1)

Publication Number Publication Date
CH387628A true CH387628A (de) 1965-02-15

Family

ID=25008358

Family Applications (1)

Application Number Title Priority Date Filing Date
CH7572959A CH387628A (de) 1958-07-14 1959-07-14 Verfahren zur Herstellung des 3-Oxy-17-Brom-9(11)pregnen-20-ons oder der entsprechenden 17,21-Dibromverbindung und deren 3-Ester

Country Status (5)

Country Link
US (1) US3013031A (de)
BE (1) BE580614A (de)
CH (1) CH387628A (de)
ES (1) ES251019A1 (de)
GB (1) GB928417A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083215A (en) * 1959-01-30 1963-03-26 Merck & Co Inc Process for preparing 16-alkyl-delta9,11-pregnenes
US3178418A (en) * 1963-02-26 1965-04-13 Glaxo Lab Ltd Monobromination at the 11-position of hecogenin and 3-lower alkanoyl esters thereof
US10711030B2 (en) * 2018-09-18 2020-07-14 Farmabios S.P.S. Process for the preparation of allopregnanolone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2656364A (en) * 1951-07-16 1953-10-20 Schering Corp Process for the manufacture of 17-keto steroids
US2752341A (en) * 1952-07-31 1956-06-26 Upjohn Co Steroid haloketones and process

Also Published As

Publication number Publication date
GB928417A (en) 1963-06-12
US3013031A (en) 1961-12-12
BE580614A (fr) 1960-01-11
ES251019A1 (es) 1959-12-16

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