CA999866A - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number: CA999866A
Authority: CA; Canada
Prior art keywords: isoquinoline derivatives; isoquinoline; derivatives
Prior art date: 1970-01-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA102,060A

Other versions

CA102060S (en

Inventor

Alfred Rheiner (Jr.)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

F Hoffmann La Roche AG

Original Assignee

F Hoffmann La Roche AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-01-06

Filing date

1971-01-06

Publication date

1976-11-16

1971-01-06 Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG

1976-11-16 Application granted granted Critical

1976-11-16 Publication of CA999866A publication Critical patent/CA999866A/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

CA102,060A 1970-01-06 1971-01-06 Isoquinoline derivatives Expired CA999866A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH10370A CH527194A (en)	1970-01-06	1970-01-06	Process for the preparation of isoquinoline derivatives

Publications (1)

Publication Number	Publication Date
CA999866A true CA999866A (en)	1976-11-16

Family

ID=4179328

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA102,060A Expired CA999866A (en)	1970-01-06	1971-01-06	Isoquinoline derivatives

Country Status (19)

Country	Link
JP (1)	JPS5515476B1 (en)
AT (1)	AT303041B (en)
BE (1)	BE761219A (en)
CA (1)	CA999866A (en)
CH (2)	CH538477A (en)
DE (1)	DE2062001C2 (en)
DK (1)	DK125021B (en)
ES (1)	ES387016A1 (en)
FI (1)	FI49503C (en)
FR (1)	FR2081412B1 (en)
GB (1)	GB1335261A (en)
IE (1)	IE34859B1 (en)
IL (1)	IL35916A (en)
NL (1)	NL171444C (en)
NO (1)	NO135315C (en)
PH (1)	PH9682A (en)
SE (3)	SE386672B (en)
YU (1)	YU33660B (en)
ZA (1)	ZA708590B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4719216A (en) *	1983-06-23	1988-01-12	Mcneilab, Inc.	Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
ZA844402B (en) *	1983-06-23	1986-01-29	Mcneil Pharmaceutical	Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) *	1983-06-23	1986-06-17	Mcneilab, Inc.	Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) *	1992-10-14	1994-04-20	Merck & Co Inc	HIV integrase inhibitors
AU781179B2 (en)	1999-11-03	2005-05-12	Albany Molecular Research, Inc.	Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) *	1999-11-03	2007-01-16	Amr Technology, Inc.	4-phenyl substituted tetrahydroisoquinolines and use thereof
RU2293728C2 (en) *	1999-11-03	2007-02-20	Эймр Текнолоджи, Инк.	Derivatives of tetrahydroisoquinoline, pharmaceutical composition containing thereof, method for inhibition of synaptic uptake of dopamine and treatment method
EP1113007A1 (en)	1999-12-24	2001-07-04	Pfizer Inc.	Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
MXPA03000275A (en)	2000-07-11	2004-12-13	Albany Molecular Res Inc	Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof.
MX2007000428A (en)	2004-07-15	2008-03-05	Amr Technology Inc	Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin.
JP2008543880A (en)	2005-06-17	2008-12-04	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Naphthyridine compounds
UA95454C2 (en)	2005-07-15	2011-08-10	Амр Текнолоджи, Інк.	Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
AR071997A1 (en)	2008-06-04	2010-07-28	Bristol Myers Squibb Co	CRYSTAL FORM OF 6 - ((4S) -2-METHYL-4- (2-NAFTIL) -1,2,3,4-TETRAHYDROISOQUINOLIN-7-IL) PIRIDAZIN-3-AMINA
US9156812B2 (en)	2008-06-04	2015-10-13	Bristol-Myers Squibb Company	Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
KR20120023072A (en)	2009-05-12	2012-03-12	브리스톨-마이어스 스큅 컴퍼니	Crystalline forms of (s)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorohphenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
MX2011011907A (en)	2009-05-12	2012-01-20	Albany Molecular Res Inc	7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4- tetrahydroisoquinoline and use thereof.
MX2011011901A (en)	2009-05-12	2012-01-20	Albany Molecular Res Inc	Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670694B2 (en) *	1966-05-05	1976-07-22	Hoechst Ag, 6000 Frankfurt	METHOD FOR MANUFACTURING TETRAHYDROISOCHINOLINES

1970
- 1970-01-06 CH CH1011872A patent/CH538477A/en not_active IP Right Cessation
- 1970-01-06 CH CH10370A patent/CH527194A/en not_active IP Right Cessation
- 1970-12-16 SE SE7313623A patent/SE386672B/en unknown
- 1970-12-16 DE DE2062001A patent/DE2062001C2/en not_active Expired
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/en unknown
- 1970-12-28 IL IL35916A patent/IL35916A/en unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/en not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/en active
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/en unknown
- 1971-01-05 AT AT4571A patent/AT303041B/en not_active IP Right Cessation
- 1971-01-05 ES ES387016A patent/ES387016A1/en not_active Expired
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-05 DK DK2571AA patent/DK125021B/en not_active IP Right Cessation
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-05 BE BE761219A patent/BE761219A/en not_active IP Right Cessation
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-06 YU YU19/71A patent/YU33660B/en unknown
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/en unknown

Also Published As

Publication number	Publication date
DE2062001A1 (en)	1971-07-15
FI49503C (en)	1975-07-10
NO135315C (en)	1977-03-23
SE368401B (en)	1974-07-01
IL35916A0 (en)	1971-02-25
SE399879B (en)	1978-03-06
GB1335261A (en)	1973-10-24
JPS5515476B1 (en)	1980-04-23
YU33660B (en)	1977-12-31
NL171444C (en)	1983-04-05
IE34859B1 (en)	1975-09-03
FR2081412B1 (en)	1974-04-12
NL7018956A (en)	1971-07-08
IL35916A (en)	1973-11-28
IE34859L (en)	1971-07-06
PH9682A (en)	1976-02-10
AT303041B (en)	1972-11-10
ZA708590B (en)	1971-09-29
CH527194A (en)	1972-08-31
NL171444B (en)	1982-11-01
YU1971A (en)	1977-06-30
DK125021B (en)	1972-12-18
CH538477A (en)	1973-06-30
FI49503B (en)	1975-04-01
FR2081412A1 (en)	1971-12-03
BE761219A (en)	1971-07-05
ES387016A1 (en)	1976-05-01
NO135315B (en)	1976-12-13
DE2062001C2 (en)	1986-10-16
SE386672B (en)	1976-08-16

Publication	Publication Date	Title
AU451793B2 (en)	1974-08-15	Pyridoquinoline derivatives
CA999866A (en)	1976-11-16	Isoquinoline derivatives
AU453008B2 (en)	1974-09-19	Triazolobenzodiazepine derivatives
CA919668A (en)	1973-01-23	Morphinan derivatives
AU466630B2 (en)	1975-11-06	Ergolene derivatives
CA1014574A (en)	1977-07-26	Phenylisopropylamine derivatives
AU448423B2 (en)	1974-05-16	Triazolobenzodiazepine derivatives
AU454027B2 (en)	1974-10-17	Tetrahydroisoquinoline derivatives
AU3306971A (en)	1973-03-08	Leucauramine derivatives
CA843952A (en)	1970-06-09	Isoquinoline derivatives
AU452845B2 (en)	1972-07-06	Isoquinoline derivatives
AU446117B2 (en)	1974-03-14	Dihydropyrimidopyridazine derivatives
CA848977A (en)	1970-08-11	Tetrahydroisoquinoline derivatives
AU2385870A (en)	1972-07-06	Isoquinoline derivatives
AU2648271A (en)	1972-09-14	2-amino-imidazol-2-ine derivatives
AU454706B2 (en)	1972-12-21	Novel morphinan derivatives
AU448194B2 (en)	1972-08-17	Dibenzothiopene derivatives
CA835400A (en)	1970-02-24	Indenopyridine derivatives
CA837631A (en)	1970-03-24	Sulfonamidoindole derivatives
CA837137A (en)	1970-03-17	Penta-chlorobenzylidenamine derivatives
AU439043B2 (en)	1971-09-16	Puridazone derivatives
AU442249B2 (en)	1971-12-23	Terahydrocyclopropadibenzazepine derivatives
AU443255B2 (en)	1972-06-15	Evomonoside derivatives
AU453581B2 (en)	1971-10-14	Indenopyridine derivatives
AU444748B2 (en)	1972-05-18	Aryloxyalkylmorpholine derivatives