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CA992958A - Hypocalcaemic peptides and processes for their manufacture - Google Patents

Hypocalcaemic peptides and processes for their manufacture

Info

Publication number
CA992958A
CA992958A CA034,471A CA34471A CA992958A CA 992958 A CA992958 A CA 992958A CA 34471 A CA34471 A CA 34471A CA 992958 A CA992958 A CA 992958A
Authority
CA
Canada
Prior art keywords
hypocalcaemic
peptides
manufacture
processes
hypocalcaemic peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA034,471A
Inventor
Robert Neher
Friedrich W. Kahnt
Max Brugger
Bruno Kamber
Werner Rittel
Peter Sieber
Bernhard Riniker
Herbert Zuber
Hendrik M. Greven
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1566167A external-priority patent/CH517074A/en
Priority claimed from CH176368A external-priority patent/CH529105A/en
Priority claimed from CH699968A external-priority patent/CH498805A/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA992958A publication Critical patent/CA992958A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA034,471A 1967-11-09 1968-11-06 Hypocalcaemic peptides and processes for their manufacture Expired CA992958A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CH1566167A CH517074A (en) 1967-11-09 1967-11-09 Hypocalcaemic peptides - with anti-inflammatory activity
CH176368A CH529105A (en) 1968-02-06 1968-02-06 Preparation of hypocalcaemic peptides
CH634768 1968-04-29
CH666668 1968-05-04
CH699968A CH498805A (en) 1968-05-10 1968-05-10 Prepn. of cystine-contg. peptides - used in the synthesis of long-chain peptides
CH750968 1968-05-21
US81810969A 1969-04-24 1969-04-24

Publications (1)

Publication Number Publication Date
CA992958A true CA992958A (en) 1976-07-13

Family

ID=27561059

Family Applications (1)

Application Number Title Priority Date Filing Date
CA034,471A Expired CA992958A (en) 1967-11-09 1968-11-06 Hypocalcaemic peptides and processes for their manufacture

Country Status (6)

Country Link
BE (1) BE723588A (en)
CA (1) CA992958A (en)
DE (1) DE1806135A1 (en)
FR (1) FR1593126A (en)
GB (1) GB1243035A (en)
NL (1) NL6815962A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801175A1 (en) * 1978-01-12 1979-07-19 Hoechst Ag PROCESS FOR THE PRODUCTION OF CYSTEIN-CONTAINING PEPTIDES
AU673237B2 (en) * 1992-12-31 1996-10-31 University Of Washington Derivatized calcitonins
US5698672A (en) * 1995-04-04 1997-12-16 Zymogenetics, Inc. Synthetic calcitonin mimetics

Also Published As

Publication number Publication date
GB1243035A (en) 1971-08-18
NL6815962A (en) 1969-05-13
FR1593126A (en) 1970-05-25
BE723588A (en) 1969-05-08
DE1806135A1 (en) 1969-07-17

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