CA953725A - Isothioureas and their derivatives - Google Patents

Isothioureas and their derivatives

Info

Publication number: CA953725A
Authority: CA; Canada
Prior art keywords: isothioureas; derivatives
Prior art date: 1969-10-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA096,673A

Other versions

CA96673S (en

Inventor

James W. Black

Graham J. Durant

Charon R. Ganellin

John C. Emmett

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Smith Kline and French Laboratories Ltd

Original Assignee

Smith Kline and French Laboratories Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-10-29

Filing date

1970-10-27

Publication date

1974-08-27

1970-10-27 Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd

1974-04-19 Priority to CA197,880A priority Critical patent/CA987592A/en

1974-08-27 Application granted granted Critical

1974-08-27 Publication of CA953725A publication Critical patent/CA953725A/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CA096,673A 1969-10-29 1970-10-27 Isothioureas and their derivatives Expired CA953725A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA197,880A CA987592A (en)	1969-10-29	1974-04-19	Histamine inhibiting compositions containing (s-(2-(4(5)-imidazolyl)ethyl) isothiourea

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB5289069		1969-10-29

Publications (1)

Publication Number	Publication Date
CA953725A true CA953725A (en)	1974-08-27

Family

ID=10465720

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA096,673A Expired CA953725A (en)	1969-10-29	1970-10-27	Isothioureas and their derivatives

Country Status (9)

Country	Link
JP (1)	JPS4917262B1 (en)
BE (1)	BE758145A (en)
CA (1)	CA953725A (en)
DE (1)	DE2052692A1 (en)
FR (1)	FR2070177B1 (en)
GB (1)	GB1296544A (en)
IE (1)	IE34665B1 (en)
SE (1)	SE390303B (en)
ZA (1)	ZA707150B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA938556A (en) *	1970-06-25	1973-12-18	Smith Kline And French Laboratories Limited	Pharmaceutical compositions containing thiourea derivatives
GB1338169A (en) *	1971-03-09	1973-11-21	Smith Kline French Lab	Ureas thioureas and guanidines
GB1397436A (en) *	1972-09-05	1975-06-11	Smith Kline French Lab	Heterocyclic n-cyanoguinidines
ZA782129B (en)	1977-04-20	1979-03-28	Ici Ltd	Hertocyclic derivatives
US4262125A (en) *	1979-07-23	1981-04-14	American Home Products Corporation	(1H-Imidazol-5-ylmethyl)isothioureas
IT1201523B (en) *	1982-05-18	1989-02-02	Angeli Inst Spa	HETEROCYCLYLPHENYLPHOMRAMIDIN, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE
US4520025A (en) *	1982-07-21	1985-05-28	William H. Rorer, Inc.	Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
US5321039A (en) *	1990-04-13	1994-06-14	Societe Civile Bioprojet	Method of inducing a histamine agonist action on H2 receptors
FR2660862B1 (en) *	1990-04-13	1994-09-23	Bioprojet Soc Civ	THERAPEUTIC APPLICATION OF HISTAMINE DERIVATIVES, NEW HISTAMINE DERIVATIVE AND USE OF THESE DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS.
NL9100365A (en) *	1991-02-27	1992-09-16	Seed Capital Investments	New imidazole compounds with activity at histamine H3 receptor - e.g. S-(2-(4-imidazolyl)ethyl)isothiourea (VUF 8325)
CA2104946A1 (en) *	1991-02-27	1992-08-28	Hendrik Timmerman	Imidazole-derivatives having agonistic or antagonistic activity on the histamine h3-receptor
GB0404434D0 (en) *	2004-02-27	2004-03-31	Novartis Ag	Organic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2548746A (en) *	1947-10-10	1951-04-10	Sharp & Dohme Inc	S-(4-thiazolylmethyl)-isothioureas
IL25931A (en) *	1965-07-07	1972-01-27	Merck & Co Inc	New 4-or 5-nitro imidazole and 5,6-dihydroimidazo(1,2-a)pyrrol-7-yl-carbamates and pseudo thioureido imidazoles and their preparation

0
- BE BE758145D patent/BE758145A/en unknown
1969
- 1969-10-29 GB GB5289069A patent/GB1296544A/en not_active Expired
1970
- 1970-10-19 IE IE1345/70A patent/IE34665B1/en unknown
- 1970-10-22 SE SE7014259A patent/SE390303B/en unknown
- 1970-10-24 JP JP45093878A patent/JPS4917262B1/ja active Pending
- 1970-10-27 DE DE19702052692 patent/DE2052692A1/en active Pending
- 1970-10-27 CA CA096,673A patent/CA953725A/en not_active Expired
- 1970-10-29 FR FR7039077A patent/FR2070177B1/fr not_active Expired
- 1970-10-29 ZA ZA707150A patent/ZA707150B/en unknown

Also Published As

Publication number	Publication date
IE34665L (en)	1971-04-29
BE758145A (en)	1971-04-28
FR2070177A1 (en)	1971-09-10
FR2070177B1 (en)	1974-10-11
IE34665B1 (en)	1975-07-09
DE2052692A1 (en)	1971-05-06
SE390303B (en)	1976-12-13
JPS4917262B1 (en)	1974-04-27
GB1296544A (en)	1972-11-15
ZA707150B (en)	1971-07-28

Publication	Publication Date	Title
CA979460A (en)	1975-12-09	Phenoxy-hydroxypropylamines and their preparation
CA956956A (en)	1974-10-29	Quinazolinone derivatives and preparation thereof
CA953725A (en)	1974-08-27	Isothioureas and their derivatives
AU1874270A (en)	1972-02-17	Alkyl-19-nortestosterones and derivatives
AU451291B2 (en)	1972-05-04	Isothioureas and their derivatives
CA818573A (en)	1969-07-22	Azomethines and derivatives thereof
AU2161770A (en)	1972-05-04	Isothioureas and their derivatives
CA892576A (en)	1972-02-08	Aminolignosulfonates and preparation thereof
AU443114B2 (en)	1971-11-18	Novenamine and derivatives
CA823281A (en)	1969-09-16	2-hydroxy-4-acryloxy ethoxybenzophenones and derivatives thereof
CA811727A (en)	1969-04-29	Polyfluoro-oxetenes and derivatives thereof
CA828161A (en)	1969-11-25	Gentamicin-tetracycline derivatives and their preparation
AU453210B2 (en)	1972-01-27	Pleuromutalin derivatives and their preparation
AU1497570A (en)	1971-11-18	Novenamine and derivatives
CA816139A (en)	1969-06-24	Derivatives of reserpinediol and deserpidinediol
CA995239A (en)	1976-08-17	Phenylthioaralkylamides and 2-phenylthio-benzylamides
CA822680A (en)	1969-09-09	Azaspirodecanediones and azaspiroundecanediones
CA808659A (en)	1969-03-18	Pyrazinoylguanidines and pyrazinamidoguanidines
AU451503B2 (en)	1972-01-20	Dibenzodiasepines and pyridobenzo-diozepines
CA806213A (en)	1969-02-11	Epoxyorganofluorosilanes and amino-hydroxy derivatives thereof
CA813356A (en)	1969-05-20	Epoxyorganofluorosilanes and amino-hydroxy derivatives thereof
AU1780170A (en)	1972-01-27	Pleuromutalin derivatives and their preparation
CA827172A (en)	1969-11-11	Trialkylsilylphenyldisiloxanes and preparation
CA825174A (en)	1969-10-14	5-acyloxyuracils and their preparation
CA811733A (en)	1969-04-29	Thionophosphates and thionophosphonates and their preparation