CA945139A - PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES - Google Patents

PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES

Info

Publication number: CA945139A
Authority: CA; Canada
Prior art keywords: alpha; pregnadien; ketals; trihydroxy; dione
Prior art date: 1971-02-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA123,803A

Other languages

English (en)

Other versions

CA123803S (en

Inventor

William C. Ripka

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

EIDP Inc

Original Assignee

EI Du Pont de Nemours and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-02-01

Filing date

1971-09-27

Publication date

1974-04-09

1971-09-27 Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co

1973-05-15 Priority to CA171,446A priority Critical patent/CA943953A/en

1974-04-09 Application granted granted Critical

1974-04-09 Publication of CA945139A publication Critical patent/CA945139A/en

Status Expired legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/939—Rhizopus

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CA123,803A 1971-02-01 1971-09-27 PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES Expired CA945139A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
CA171,446A CA943953A (en)	1971-02-01	1973-05-15	PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6,9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11161571A	1971-02-01	1971-02-01

Publications (1)

Publication Number	Publication Date
CA945139A true CA945139A (en)	1974-04-09

Family

ID=22339486

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA123,803A Expired CA945139A (en)	1971-02-01	1971-09-27	PROCESS FOR THE PREPARATION OF 21-CHLORO-6,6 9.alpha.-TRIFLUORO-11.beta.,16.alpha.,17.alpha.-TRIHYDROXY-1,4-PREGNADIEN-3,20-DIONE 16,17-KETALS AND SELECTED INTERMEDIATES

Country Status (13)

Country	Link
US (1)	US3718673A (fr)
AT (1)	AT308294B (fr)
AU (1)	AU3452371A (fr)
BE (1)	BE774754A (fr)
CA (1)	CA945139A (fr)
DE (1)	DE2149798A1 (fr)
DK (1)	DK129514B (fr)
ES (1)	ES396031A1 (fr)
FR (1)	FR2124218B1 (fr)
GB (3)	GB1363460A (fr)
IL (1)	IL37798A0 (fr)
NL (1)	NL7113713A (fr)
ZA (1)	ZA716382B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7502252A (nl) *	1974-02-27	1975-08-29	Pierrel Spa	Werkwijze voor het bereiden van een geneesmid- del met anti-inflammatoire werking, gevormd ge- neesmiddel verkregen volgens deze werkwijze alsmede werkwijze voor het bereiden van in het geneesmiddel gebruikte nieuwe steroiden.
US4272446A (en) *	1974-02-27	1981-06-09	Pierrel S.P.A.	Steroids and process for preparing the same
DE2655570A1 (de) *	1975-12-12	1977-06-16	Ciba Geigy Ag	Neue polyhalogensteroide und verfahren zu ihrer herstellung
DE3173923D1 (en) *	1980-12-23	1986-04-03	Schering Ag	Process for the preparation of 11-beta, 21-dihydroxy-2'-methyl-5'-beta-h-1,4-pregnadieno-(16,17-d)-oxazole-3,20-dione
CN102061320B (zh) *	2010-12-02	2013-04-03	浙江仙琚制药股份有限公司	11α，17α-二羟基-雄甾-4-烯-3，20-二酮的制备方法
US9109005B2 (en)	2012-02-23	2015-08-18	Boehringer Ingelheim International Gmbh	Method for manufacturing of ciclesonide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3338928A (en) *	1965-09-09	1967-08-29	Syntex Corp	Fused halocyclopropyl steroids
US3546215A (en) *	1967-10-18	1970-12-08	Syntex Corp	6-gem-difluoro steroids

1971
- 1971-02-01 US US00111615A patent/US3718673A/en not_active Expired - Lifetime
- 1971-09-22 DK DK463071AA patent/DK129514B/da unknown
- 1971-09-23 ZA ZA716382A patent/ZA716382B/xx unknown
- 1971-09-24 GB GB437374A patent/GB1363460A/en not_active Expired
- 1971-09-24 GB GB4472871A patent/GB1363458A/en not_active Expired
- 1971-09-27 IL IL37798A patent/IL37798A0/xx unknown
- 1971-09-27 CA CA123,803A patent/CA945139A/en not_active Expired
- 1971-10-06 NL NL7113713A patent/NL7113713A/xx unknown
- 1971-10-06 DE DE19712149798 patent/DE2149798A1/de active Pending
- 1971-10-13 AU AU34523/71A patent/AU3452371A/en not_active Expired
- 1971-10-14 AT AT888171A patent/AT308294B/de not_active IP Right Cessation
- 1971-10-15 ES ES396031A patent/ES396031A1/es not_active Expired
- 1971-10-28 FR FR7138737A patent/FR2124218B1/fr not_active Expired
- 1971-10-29 BE BE774754A patent/BE774754A/fr unknown
1974
- 1974-01-30 GB GB437271*[A patent/GB1363459A/en not_active Expired

Also Published As

Publication number	Publication date
GB1363458A (en)	1974-08-14
SU438181A3 (ru)	1974-07-30
GB1363459A (en)	1974-08-14
FR2124218A1 (fr)	1972-09-22
DK129514C (fr)	1975-03-17
US3718673A (en)	1973-02-27
BE774754A (fr)	1972-05-02
DK129514B (da)	1974-10-21
IL37798A0 (en)	1971-11-29
ZA716382B (en)	1972-07-26
DE2149798A1 (de)	1972-08-03
FR2124218B1 (fr)	1975-03-14
ES396031A1 (es)	1975-02-16
NL7113713A (fr)	1972-08-03
AU3452371A (en)	1973-04-19
GB1363460A (en)	1974-08-14
AT308294B (de)	1973-06-25

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