[go: up one dir, main page]

CA934758A - Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates - Google Patents

Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates

Info

Publication number
CA934758A
CA934758A CA139293A CA139293A CA934758A CA 934758 A CA934758 A CA 934758A CA 139293 A CA139293 A CA 139293A CA 139293 A CA139293 A CA 139293A CA 934758 A CA934758 A CA 934758A
Authority
CA
Canada
Prior art keywords
dicarboxylates
unsymmetrical
dihydropyridine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA139293A
Other versions
CA139293S (en
Inventor
Meyer Horst
Bossert Friedrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA934758A publication Critical patent/CA934758A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA139293A 1971-04-10 1972-04-10 Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates Expired CA934758A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712117573 DE2117573C3 (en) 1971-04-10 1971-04-10 Process for the preparation of asymmetrical 1,4-dihydropyridine-3,5dicarboxylic acid esters, and their use as medicaments

Publications (1)

Publication Number Publication Date
CA934758A true CA934758A (en) 1973-10-02

Family

ID=5804435

Family Applications (1)

Application Number Title Priority Date Filing Date
CA139293A Expired CA934758A (en) 1971-04-10 1972-04-10 Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates

Country Status (19)

Country Link
JP (1) JPS5529990B1 (en)
AT (1) AT315178B (en)
BG (1) BG20105A3 (en)
CA (1) CA934758A (en)
CH (1) CH571492A5 (en)
CS (1) CS178407B2 (en)
DD (1) DD104520A5 (en)
DE (1) DE2117573C3 (en)
DK (1) DK134600C (en)
ES (1) ES401616A1 (en)
FI (1) FI55188C (en)
HU (1) HU163996B (en)
LU (1) LU65130A1 (en)
NL (1) NL170535C (en)
NO (1) NO133712C (en)
PL (1) PL83824B1 (en)
RO (1) RO61069A (en)
SE (1) SE371441B (en)
SU (1) SU421193A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622332A (en) * 1982-03-10 1986-11-11 Bayer Aktiengesellschaft Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2320750A1 (en) * 1975-08-12 1977-03-11 Hexachimie 1,4-DIHYDRO PYRIDINES AND THEIR THERAPEUTIC APPLICATION
DE2650013C3 (en) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1,4-Dihydro-2,6-dimethyl-4- (3-nitrophenyl) -3,5-pyridinedicarboxylic acid isopropyl (2-propoxy-ethyl) ester, process for its preparation and medicinal products containing it
DE2815578C2 (en) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen New pharmaceutical use of nimodipine
SE429652B (en) * 1978-06-30 1983-09-19 Haessle Ab 2,6-dimethyl-4- (2,3-dichlorophenyl) -1,4-dihydropyridine-3,5-dicarboxylic acid 3-methyl 5-ethyl ester
DE2841667A1 (en) * 1978-09-25 1980-04-10 Bayer Ag FLUORINE 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
JPS58159490A (en) * 1982-02-23 1983-09-21 Nikken Kagaku Kk 1,4-dihydropyridne compound
JPS58185562A (en) * 1982-04-22 1983-10-29 Taisho Pharmaceut Co Ltd 1,4-dihydropyridine derivative
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
US4529733A (en) * 1983-04-06 1985-07-16 Merrell Dow Pharmaceuticals Inc. Antihypertensive 3-furoyl-1,4-dihydropyridines
US4607041A (en) * 1983-04-27 1986-08-19 Fisons Plc Antihypertensive 2-phenyl Hantzsch dihydropyridines
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
EP0311053A3 (en) * 1987-10-06 1991-05-08 Banyu Pharmaceutical Co., Ltd. Ameliorant of cerebral circulation and optical isomer of nb-818, processes for its production and its use
DE3741540A1 (en) * 1987-12-08 1989-06-22 Bayer Ag METHOD FOR PRODUCING UNSYMMETRIC DIHYDROPYRIDINES
ES2193148T3 (en) * 1993-12-10 2003-11-01 Bayer Ag 1,4-DIHYDROPIRIDINES REPLACED WITH PHENYLLUS WITH BRAIN ACTIVITY.
US5977369A (en) * 1995-12-28 1999-11-02 Napp Technologies, Inc. Process to prepare dihydropyridine and derivatives thereof
IT1283793B1 (en) * 1996-08-23 1998-04-30 Lusochimica Spa DIHYDROPYRIDINE PREPARATION PROCESS
AU8430098A (en) * 1998-07-23 2000-02-14 Ing-Jun Chen Guaiacoxypropanolamines with alpha/beta-adrenergic blocking activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622332A (en) * 1982-03-10 1986-11-11 Bayer Aktiengesellschaft Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity

Also Published As

Publication number Publication date
DE2117573A1 (en) 1972-10-19
NL170535B (en) 1982-06-16
HU163996B (en) 1973-12-28
FI55188C (en) 1979-06-11
NO133712C (en) 1976-06-16
DE2117573C3 (en) 1978-07-27
NL7204695A (en) 1972-10-12
PL83824B1 (en) 1976-02-28
RO61069A (en) 1976-11-15
DE2117573B2 (en) 1977-12-01
LU65130A1 (en) 1972-07-12
DK134600B (en) 1976-12-06
FI55188B (en) 1979-02-28
CS178407B2 (en) 1977-09-15
CH571492A5 (en) 1976-01-15
DD104520A5 (en) 1974-03-12
BG20105A3 (en) 1975-10-30
JPS5529990B1 (en) 1980-08-07
ES401616A1 (en) 1975-02-16
SE371441B (en) 1974-11-18
SU421193A3 (en) 1974-03-25
NL170535C (en) 1982-11-16
NO133712B (en) 1976-03-08
DK134600C (en) 1977-05-16
AT315178B (en) 1974-05-10

Similar Documents

Publication Publication Date Title
CA925513A (en) Process for the preparation of unsymmetrical esters of 3,5-dicarboxylates
CA921035A (en) Process for the preparation of unsymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid
CA934758A (en) Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates
CA995693A (en) Process for the preparation of dihydroxybenzenes
CA979891A (en) N(6)-aralkyl-adenosine derivatives and process for the preparation thereof
CA972744A (en) PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXYSTEROIDS
GB1400485A (en) Process for the manufacture of 8-oxo-5-thia-1-azabicyclo- 4,2,0-oct-2-ene or -3-ene compounds
CA949980A (en) Process for the preparation of 2,2,2-trifluoroethyl-difluoromethyl ether
AU468153B2 (en) Process for the preparation of 2, 2'-bipyridyls
CA978954A (en) Preparation of 2,4-diamino-5-benzylpyrimidines
CA944135A (en) Apparatus for the manufacture of novel 1,2-dihydroquinolines
CA981699A (en) Process for the continuous manufacture of 3,4-dichlorobutene-1
CA1006522A (en) N-acyl-(piperazinoalkyl)-pyrazoles and process for the preparation thereof
CA981697A (en) Process for the manufacture of 3,4-dichlorobutene-1
IE42100L (en) Process for the preparation of 2, 2, 2-trichloroethyl¹chloroformate
ATA399872A (en) Process for the preparation of a 1,4-dihydropyridine derivative
CA979001A (en) Process for the preparation of 2,6-naphthalenedicarboxylic acid
CA992983A (en) 1,4-methano-and ethano-tetrahydronaphthyloxypropanols and process for their preparation
CA981698A (en) Process for the manufacture of 3,4-dichlorobutene-1
IL40917A0 (en) The preparation of 4-substituted-1-(4,4-diarylbutyl)-piperidines
AU462890B2 (en) Process for the preparation of 1,2-dihydroquinolines
CA880334A (en) Process for the preparation of 6, 7-epoxycitronellal
CA885455A (en) Process for the preparation of 9-aminoalkyl-1,2,8,9-tetraazaphenalenes
CA888759A (en) Process for the manufacture of 3,3'-5,5'-tetrachloro-4,4'-dihydroxy-diphenylsulphone
CA873875A (en) Process for the manufacture of 1,4-dihalogenanthraquinones