CA2849506C - Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor - Google Patents
Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor Download PDFInfo
- Publication number
- CA2849506C CA2849506C CA2849506A CA2849506A CA2849506C CA 2849506 C CA2849506 C CA 2849506C CA 2849506 A CA2849506 A CA 2849506A CA 2849506 A CA2849506 A CA 2849506A CA 2849506 C CA2849506 C CA 2849506C
- Authority
- CA
- Canada
- Prior art keywords
- cassette
- tissue
- embedding
- tissue sample
- microtome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title description 29
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 210000001519 tissue Anatomy 0.000 description 89
- 239000012188 paraffin wax Substances 0.000 description 21
- 230000008569 process Effects 0.000 description 13
- 238000001574 biopsy Methods 0.000 description 11
- 239000000463 material Substances 0.000 description 6
- 239000012530 fluid Substances 0.000 description 3
- 230000007170 pathology Effects 0.000 description 3
- 238000010186 staining Methods 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- 230000001627 detrimental effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 208000012514 Cumulative Trauma disease Diseases 0.000 description 1
- 208000037273 Pathologic Processes Diseases 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 208000026062 Tissue disease Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 208000003295 carpal tunnel syndrome Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003722 extracellular fluid Anatomy 0.000 description 1
- 239000000834 fixative Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002962 histologic effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 238000010827 pathological analysis Methods 0.000 description 1
- 230000009054 pathological process Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/54—Labware with identification means
- B01L3/545—Labware with identification means for laboratory containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/02—Identification, exchange or storage of information
- B01L2300/021—Identification, e.g. bar codes
- B01L2300/022—Transponder chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/315—Basket-type carriers for tissues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51214703P | 2003-10-17 | 2003-10-17 | |
| US60/512,147 | 2003-10-17 | ||
| CA2542323A CA2542323C (en) | 2003-10-17 | 2004-10-12 | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2542323A Division CA2542323C (en) | 2003-10-17 | 2004-10-12 | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2849506A1 CA2849506A1 (en) | 2005-04-28 |
| CA2849506C true CA2849506C (en) | 2016-05-10 |
Family
ID=34465316
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2849506A Expired - Lifetime CA2849506C (en) | 2003-10-17 | 2004-10-12 | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
| CA2542323A Expired - Lifetime CA2542323C (en) | 2003-10-17 | 2004-10-12 | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2542323A Expired - Lifetime CA2542323C (en) | 2003-10-17 | 2004-10-12 | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1682272A4 (zh) |
| JP (1) | JP4584259B2 (zh) |
| CN (1) | CN1898022B (zh) |
| BR (1) | BRPI0415516A (zh) |
| CA (2) | CA2849506C (zh) |
| WO (1) | WO2005037182A2 (zh) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2322938T3 (da) | 2002-09-26 | 2013-04-08 | Biopath Automation Llc | Apparat og fremgangsmåde til automatisk håndtering og indlejring af vævsprøver |
| US7179424B2 (en) | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
| US20070116612A1 (en) * | 2005-11-02 | 2007-05-24 | Biopath Automation, L.L.C. | Prefix tissue cassette |
| WO2007074769A1 (ja) * | 2005-12-27 | 2007-07-05 | Kyoto University | 生物組織固定・包埋・薄切用カセット及びその操作方法 |
| WO2008073387A1 (en) | 2006-12-12 | 2008-06-19 | Biopath Automation, L.L.C. | Biopsy support with sectionable resilient cellular material |
| EP2027922A1 (de) | 2007-08-02 | 2009-02-25 | Qiagen GmbH | Verfahren und Vorrichtung für das Fixieren/Stabilisieren einer Probe |
| MX2010004419A (es) | 2007-10-23 | 2010-05-05 | Becton Dickinson Co | Kit cerrado para la contencion y estabilizacion tisular para diagnosticos moleculares e histopatologicos. |
| ES2425266T3 (es) * | 2007-10-23 | 2013-10-14 | Becton, Dickinson And Company | Sistema de múltiples cámaras para contención de tejido para diagnóstico molecular e histológico |
| JP5230209B2 (ja) * | 2008-01-18 | 2013-07-10 | 悌二 竹崎 | 臨床側と病理検査側で共通使用する収納容器の構築形成体（枠状基体）を介して臨床側と病理検査側間での患者試料データの確実な伝達・連結をする病理組織試料用固定移送容器と病理組織試料用カセット。 |
| JP5030841B2 (ja) * | 2008-04-07 | 2012-09-19 | 村角工業株式会社 | 病理組織検査標本作成用の包埋トレイ |
| WO2010085626A1 (en) | 2009-01-22 | 2010-07-29 | Biopath Automation, L.L.C. | Microtome sectionable biopsy support for orienting tissue samples |
| NL2002967C2 (en) * | 2009-06-04 | 2011-01-04 | Intresco B V | A method to turn biological tissue sample cassettes into traceable devices, using a system with inlays tagged with radio frequency identification (rfid) chips. |
| JP2012032238A (ja) * | 2010-07-29 | 2012-02-16 | Sakura Seiki Kk | 組織アレイの作製方法 |
| JP6189946B2 (ja) | 2012-06-22 | 2017-08-30 | ライカ ビオズュステムス ヌスロッホ ゲーエムベーハー | 生検組織試料搬送装置及びその使用方法 |
| ES2832554T3 (es) | 2012-06-22 | 2021-06-10 | Leica Biosystems Nussloch Gmbh | Recipiente para muestras de tejido |
| CA2845832C (en) | 2013-03-15 | 2020-09-22 | Leica Biosystems Nussloch Gmbh | Tissue cassette with biasing element |
| US9052256B2 (en) | 2013-03-15 | 2015-06-09 | Leica Biosystems Nussloch Gmbh | Method for processing and embedding tissue |
| CA2845830C (en) | 2013-03-15 | 2020-10-27 | Leica Biosystems Nussloch Gmbh | Tissue cassette with retractable member |
| DE102013225397A1 (de) * | 2013-12-10 | 2015-06-11 | Leica Biosystems Nussloch Gmbh | Einbettautomat und Verfahren zum Einbetten einer histologischen Probe |
| US10634590B2 (en) | 2014-03-11 | 2020-04-28 | Emd Millipore Corporation | IHC, tissue slide fluid exchange disposable and system |
| EP3401665A1 (en) * | 2017-05-12 | 2018-11-14 | University College Dublin National University Of Ireland, Dublin | A system and device for analysis of specific matter in liquid samples by optical microscopy |
| DE202018104076U1 (de) | 2018-03-15 | 2018-07-23 | Leica Biosystems Nussloch Gmbh | Halter für einen Stapel von Deckgläsern und Deckglasstapelvorratshalter |
| CN109916681A (zh) * | 2019-03-10 | 2019-06-21 | 西安培华学院 | 一种数字病理切片的移动装置 |
| GB2600091B (en) * | 2020-10-12 | 2025-02-19 | Cellpath Ltd | Cassette assembly and processing method |
| WO2024221380A1 (en) * | 2023-04-28 | 2024-10-31 | Leica Biosystems Nussloch Gmbh | Tissue cassette and tissue embedding assembly |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8415648D0 (en) * | 1984-06-19 | 1984-07-25 | Mclean W | Identification of histology samples |
| NZ212428A (en) * | 1984-06-19 | 1988-05-30 | William Mcclean | Identification marker for identification of histology samples |
| USD330257S (en) * | 1990-05-30 | 1992-10-13 | Zynaxis Technologies, Inc. | Reagent tray |
| US5272093A (en) * | 1990-08-02 | 1993-12-21 | Miles Inc. | Reagent containment and delivery tray and method of use |
| US5080869A (en) * | 1990-08-14 | 1992-01-14 | Mccormick James B | Apparatus and method for preparing tissue samples for histological examination |
| US5279800A (en) * | 1992-11-25 | 1994-01-18 | C/T Med-Systems Ltd., Inc. | Dental cassette kit |
| US5609827A (en) * | 1995-05-02 | 1997-03-11 | Beekley Corporation | Biopsy specimen container |
| US5817032A (en) * | 1996-05-14 | 1998-10-06 | Biopath Automation Llc. | Means and method for harvesting and handling tissue samples for biopsy analysis |
| US6489171B1 (en) * | 1997-04-18 | 2002-12-03 | Cell Marque Corporation | Chemical dispensing system and method |
| US6289682B1 (en) * | 1999-08-25 | 2001-09-18 | David C. Rada | Specimen preparation apparatus |
| DE10154843A1 (de) * | 2001-11-08 | 2003-05-28 | Microm Int Gmbh | Verfahren und Vorrichtung zur Kennzeichnung von Objektträgern für mikrotomierte Gewebeproben und deren Bearbeitung |
| DK2322938T3 (da) * | 2002-09-26 | 2013-04-08 | Biopath Automation Llc | Apparat og fremgangsmåde til automatisk håndtering og indlejring af vævsprøver |
-
2004
- 2004-10-12 CA CA2849506A patent/CA2849506C/en not_active Expired - Lifetime
- 2004-10-12 EP EP04794852A patent/EP1682272A4/en not_active Ceased
- 2004-10-12 CN CN200480036600.8A patent/CN1898022B/zh not_active Expired - Lifetime
- 2004-10-12 BR BRPI0415516-5A patent/BRPI0415516A/pt not_active IP Right Cessation
- 2004-10-12 WO PCT/US2004/033604 patent/WO2005037182A2/en active Search and Examination
- 2004-10-12 CA CA2542323A patent/CA2542323C/en not_active Expired - Lifetime
- 2004-10-12 JP JP2006535585A patent/JP4584259B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2542323C (en) | 2014-08-12 |
| CN1898022A (zh) | 2007-01-17 |
| BRPI0415516A (pt) | 2006-12-26 |
| EP1682272A2 (en) | 2006-07-26 |
| CN1898022B (zh) | 2011-04-06 |
| JP4584259B2 (ja) | 2010-11-17 |
| CA2849506A1 (en) | 2005-04-28 |
| WO2005037182A3 (en) | 2006-01-12 |
| EP1682272A4 (en) | 2008-05-28 |
| CA2542323A1 (en) | 2005-04-28 |
| JP2007508569A (ja) | 2007-04-05 |
| WO2005037182A2 (en) | 2005-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140422 |