[go: up one dir, main page]

CA2807508A1 - Implant sous-conjonctival pour une administration d'un medicament dans le segment posterieur - Google Patents

Implant sous-conjonctival pour une administration d'un medicament dans le segment posterieur Download PDF

Info

Publication number
CA2807508A1
CA2807508A1 CA2807508A CA2807508A CA2807508A1 CA 2807508 A1 CA2807508 A1 CA 2807508A1 CA 2807508 A CA2807508 A CA 2807508A CA 2807508 A CA2807508 A CA 2807508A CA 2807508 A1 CA2807508 A1 CA 2807508A1
Authority
CA
Canada
Prior art keywords
therapeutic
therapeutic agent
container
therapeutic device
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2807508A
Other languages
English (en)
Inventor
Yair Alster
Eugene De Juan, Jr.
Kathleen Cogan Farinas
K. Angela Macfarlane
Cary J. Reich
Randolph E. Campbell
Signe Erickson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ForSight Vision4 Inc
Original Assignee
ForSight Vision4 Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ForSight Vision4 Inc filed Critical ForSight Vision4 Inc
Publication of CA2807508A1 publication Critical patent/CA2807508A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA2807508A 2010-08-05 2011-08-04 Implant sous-conjonctival pour une administration d'un medicament dans le segment posterieur Abandoned CA2807508A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37114410P 2010-08-05 2010-08-05
US61/371,144 2010-08-05
PCT/US2011/046650 WO2012019047A2 (fr) 2010-08-05 2011-08-04 Implant sous-conjonctival pour une administration d'un médicament dans le segment postérieur

Publications (1)

Publication Number Publication Date
CA2807508A1 true CA2807508A1 (fr) 2012-02-09

Family

ID=45560080

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2807508A Abandoned CA2807508A1 (fr) 2010-08-05 2011-08-04 Implant sous-conjonctival pour une administration d'un medicament dans le segment posterieur

Country Status (5)

Country Link
US (1) US20130274692A1 (fr)
EP (1) EP2600920A4 (fr)
AU (1) AU2011285637B2 (fr)
CA (1) CA2807508A1 (fr)
WO (1) WO2012019047A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015060812A1 (fr) * 2013-10-21 2015-04-30 Howard University Traitement d'une maladie oculaire par des inhibiteurs des transporteurs d'efflux

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010208046B2 (en) 2009-01-29 2014-10-02 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
EP2600930B1 (fr) 2010-08-05 2021-02-17 ForSight Vision4, Inc. Appareil d'injection pour l'administration de médicaments
PT2600812T (pt) 2010-08-05 2021-11-09 Forsight Vision4 Inc Aparelho para tratar um olho
CA2807537C (fr) 2010-08-05 2018-09-18 Forsight Vision4, Inc. Procedes et appareils d'administration combinee de medicament
WO2012068549A2 (fr) 2010-11-19 2012-05-24 Forsight Vision4, Inc. Formulations d'agents thérapeutiques pour des dispositifs implantés
EP2726016B1 (fr) 2011-06-28 2023-07-19 ForSight Vision4, Inc. Un appareil pour collecter un échantillon de fluide à partir d'une chambre réservoir d'un dispositif thérapeutique pour l'oeil
HRP20210676T1 (hr) 2011-09-16 2021-05-28 Forsight Vision4, Inc. Uređaj za izmjenu fluida
WO2013116061A1 (fr) 2012-02-03 2013-08-08 Forsight Vision4, Inc. Procédés et instrument pour l'insertion et le retrait de dispositifs thérapeutiques
HRP20211572T1 (hr) 2012-06-01 2022-02-04 Novartis Ag Štrcaljka
US10251778B2 (en) 2012-08-06 2019-04-09 Baylor College Of Medicine Therapeutics dispensing device and methods of making same
WO2014152959A1 (fr) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systèmes pour l'administration intra-oculaire entretenue de composés à faible solubilité provenant d'un implant de système de pose d'orifice
US9597227B2 (en) * 2013-03-15 2017-03-21 Abbott Medical Optics Inc. Trans-sclera portal for delivery of therapeutic agents
CA2907681C (fr) 2013-03-28 2022-11-22 Forsight Vision4, Inc. Implant ophtalmique pour administrer des substances therapeutiques
US20160302965A1 (en) 2013-12-06 2016-10-20 Forsight Vision4, Inc. Implantable therapeutic devices
EP3679908B1 (fr) 2014-07-15 2024-09-04 ForSight Vision4, Inc. Dispositif de pose d'implant oculaire
CA2957548A1 (fr) 2014-08-08 2016-02-11 Forsight Vision4, Inc. Formulations stables et solubles d'inhibiteurs de la tyrosine kinase de recepteurs, et procedes de preparation de ces dernieres
US10500091B2 (en) 2014-11-10 2019-12-10 Forsight Vision4, Inc. Expandable drug delivery devices and methods of use
EP3340982B1 (fr) 2015-08-26 2021-12-15 Achillion Pharmaceuticals, Inc. Composés pour le traitement de troubles immunitaires et inflammatoires
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
CN108137681B (zh) 2015-09-23 2024-06-18 豪夫迈·罗氏有限公司 抗-vegf抗体的优化的变体
JP6912475B2 (ja) * 2015-11-20 2021-08-04 フォーサイト・ビジョン フォー・インコーポレーテッドForsight Vision4, Inc. 持続放出性薬物送達機器用の多孔質構造体
KR20180133440A (ko) 2016-04-05 2018-12-14 포사이트 비젼4, 인크. 이식 가능한 안구 약물 전달 장치
WO2017197051A1 (fr) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Dégronimères de c3-glutarimide liés à une amine pour la dégradation de protéines cibles
RU2018145364A (ru) 2016-06-27 2020-07-28 Ачиллион Фармасьютикалс, Инк. Хиназолиновые и индольные соединения для лечения медицинских нарушений
US10874768B2 (en) * 2017-01-20 2020-12-29 Covidien Lp Drug eluting medical device
IL294069B2 (en) 2017-03-01 2023-11-01 Achillion Pharmaceuticals Inc Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders
PE20191758A1 (es) 2017-03-22 2019-12-12 Genentech Inc Composiciones de anticuerpo optimizadas para el tratamiento de trastornos oculares
EP3713528A1 (fr) 2017-11-21 2020-09-30 ForSight Vision4, Inc. Appareil d'échange de fluide pour système d'administration à port extensible et méthodes d'utilisation
CN111432868A (zh) * 2017-12-05 2020-07-17 马奎特紧急护理公司 刺穿组件和呼吸导管套件
JP2021519337A (ja) 2018-03-26 2021-08-10 シー4 セラピューティクス, インコーポレイテッド Ikarosの分解のためのセレブロン結合剤
JOP20200275A1 (ar) 2018-05-10 2020-11-02 Regeneron Pharma صيغ تحتوي على بروتين اندماج لمستقبلvegf مرتفعة التركيز
EP3841086B1 (fr) 2018-08-20 2025-04-23 Achillion Pharmaceuticals, Inc. Composés pharmaceutiques pour le traitement de troubles médicaux liés au facteur d du complément
EP3846803A4 (fr) 2018-09-06 2022-08-10 Achillion Pharmaceuticals, Inc. Composés macrocycliques pour le traitement de troubles médicaux
WO2020081723A1 (fr) 2018-10-16 2020-04-23 Georgia State University Research Foundation, Inc. Promédicaments de monoxyde de carbone pour le traitement de troubles médicaux
CN109431678B (zh) * 2018-12-17 2021-05-28 中国医学科学院北京协和医院 经巩膜药物传输系统
US20220347167A1 (en) * 2019-10-05 2022-11-03 The Schepens Eye Research Institute, Inc. A new treatment for meibomian gland dysfunction
EP4107166A4 (fr) 2020-02-20 2024-06-26 Achillion Pharmaceuticals, Inc. Composés hétéroaryle pour le traitement de troubles médiés par le facteur d du complément
EP4114392A4 (fr) 2020-03-05 2024-04-10 C4 Therapeutics, Inc. Composés pour la dégradation ciblée de la brd9
CA3193163A1 (fr) 2020-09-04 2022-03-10 F. Hoffmann-La Roche Ag Anticorps se liant a vegf-a et a ang2 et methodes d'utilisation
WO2022066774A1 (fr) 2020-09-23 2022-03-31 Achillion Pharmaceuticals, Inc. Composés pharmaceutiques pour le traitement de troubles à médiation par complément
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
AR129268A1 (es) 2022-05-11 2024-08-07 Hoffmann La Roche Anticuerpo que se une a vegf-a e il6 y métodos de uso
EP4547299A1 (fr) * 2022-07-01 2025-05-07 Genentech Inc. Système de réservoir d'administration de médicament implantable et rechargeable avec fritte métallique poreuse pour administration intracérébroventriculaire prolongée et procédés d'utilisation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466233A (en) * 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US20050244472A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intraocular drug delivery systems containing excipients with reduced toxicity and related methods
US20070212397A1 (en) * 2005-09-15 2007-09-13 Roth Daniel B Pharmaceutical delivery device and method for providing ocular treatment
US20080167600A1 (en) * 2005-09-26 2008-07-10 Peyman Gholam A Device for delivery of an agent to the eye and other sites
US8168584B2 (en) * 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
CA2723753A1 (fr) * 2008-05-08 2009-11-12 Replenish Pumps, Llc Pompes d'administration de medicament et procedes de fabrication
US20100174272A1 (en) * 2009-01-02 2010-07-08 Weiner Alan L In-situ refillable ophthalmic implant
EP3785683B1 (fr) * 2009-05-18 2023-11-01 Dose Medical Corporation Implant oculaire à élution de médicament

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015060812A1 (fr) * 2013-10-21 2015-04-30 Howard University Traitement d'une maladie oculaire par des inhibiteurs des transporteurs d'efflux

Also Published As

Publication number Publication date
WO2012019047A2 (fr) 2012-02-09
AU2011285637B2 (en) 2014-10-30
EP2600920A2 (fr) 2013-06-12
EP2600920A4 (fr) 2017-10-04
WO2012019047A3 (fr) 2012-05-10
US20130274692A1 (en) 2013-10-17
AU2011285637A1 (en) 2013-03-07

Similar Documents

Publication Publication Date Title
US11679027B2 (en) Combined drug delivery methods and apparatus
US20230338282A1 (en) Posterior segment drug delivery
US10813788B2 (en) Implantable therapeutic device
US20130274692A1 (en) Subconjuctival implant for posterior segment drug delivery
US10166142B2 (en) Small molecule delivery with implantable therapeutic device
AU2011285501B2 (en) Implantable therapeutic device
HK40068549A (en) Implantable therapeutic device
HK1164761B (en) Posterior segment drug delivery
HK1164761A (en) Posterior segment drug delivery

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20160722

FZDE Discontinued

Effective date: 20181207