CA2650966A1 - Vented infusion access device - Google Patents
Vented infusion access device Download PDFInfo
- Publication number
- CA2650966A1 CA2650966A1 CA002650966A CA2650966A CA2650966A1 CA 2650966 A1 CA2650966 A1 CA 2650966A1 CA 002650966 A CA002650966 A CA 002650966A CA 2650966 A CA2650966 A CA 2650966A CA 2650966 A1 CA2650966 A1 CA 2650966A1
- Authority
- CA
- Canada
- Prior art keywords
- housing
- fluid path
- infusion
- spike
- distal end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001802 infusion Methods 0.000 title claims abstract description 116
- 231100000331 toxic Toxicity 0.000 claims abstract description 26
- 230000002588 toxic effect Effects 0.000 claims abstract description 26
- 239000000463 material Substances 0.000 claims abstract description 24
- 238000013022 venting Methods 0.000 claims abstract description 10
- 239000012530 fluid Substances 0.000 claims description 82
- 238000004891 communication Methods 0.000 claims description 13
- 239000012528 membrane Substances 0.000 claims description 11
- 230000002209 hydrophobic effect Effects 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 7
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 239000003814 drug Substances 0.000 description 25
- 229940079593 drug Drugs 0.000 description 25
- 231100001261 hazardous Toxicity 0.000 description 6
- 238000011109 contamination Methods 0.000 description 3
- 239000000824 cytostatic agent Substances 0.000 description 3
- 230000001085 cytostatic effect Effects 0.000 description 3
- 231100000433 cytotoxic Toxicity 0.000 description 3
- 230000001472 cytotoxic effect Effects 0.000 description 3
- 241000272525 Anas platyrhynchos Species 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000005336 cracking Methods 0.000 description 2
- 239000013056 hazardous product Substances 0.000 description 2
- 229920005669 high impact polystyrene Polymers 0.000 description 2
- 239000004797 high-impact polystyrene Substances 0.000 description 2
- 239000003978 infusion fluid Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- -1 polybutylene terephthalate Polymers 0.000 description 2
- 229920001707 polybutylene terephthalate Polymers 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- BHMLFPOTZYRDKA-IRXDYDNUSA-N (2s)-2-[(s)-(2-iodophenoxy)-phenylmethyl]morpholine Chemical compound IC1=CC=CC=C1O[C@@H](C=1C=CC=CC=1)[C@H]1OCCNC1 BHMLFPOTZYRDKA-IRXDYDNUSA-N 0.000 description 1
- 241000518994 Conta Species 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000012387 aerosolization Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012829 chemotherapy agent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 230000005661 hydrophobic surface Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000007913 intrathecal administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 239000011112 polyethylene naphthalate Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 238000009834 vaporization Methods 0.000 description 1
- 230000008016 vaporization Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
- A61M2005/1623—Details of air intake
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Device for accessing a toxic material, comprising a vented infusion access device for connection to an infusion container. The access device comprises a multi-lumen spike for connecting to the infusion container, connector means for accessing the infusion container, and venting means. The device is provided with a one-way check valve for safely providing and/or accessing toxic material of the infusion container while preventing or eliminating exposure to toxic material during access.
Description
VENTED INFUSION ACCESS DEVICE
BACKGROUND OF THE INVENTION
Field of the Invention The present invention relates to a device for accessing an infusioneontainer, which may contain a toxic material, comprising a vented infusion access device for connection to the infusioari container. The device is provided with a spike for connection with the infusion container, the spike comprising at least two lumens for accessing, delivering a fluid, and venting.
Within the medical industry, medical persoluiel may be required to handle cytotoxic drugs, sometimes on a daily basis. A class of cytotoxic drugs is cytostatic chemotherapy agents. It is genet=a11y believed that cytostatics and some antibiotics may cause health problems if inhaled or exposed to the skin. Exposure or inhalation may be through leakage, aerosolization, or vaporization into the working environment during handling of the cytostatics.
When administering a drug via an infusion set, it is a common practice to use a spike to access the contents of the infusion container. In many cases, wlhen the spike piei-ces the septum of the infusion container, fluid leaks before the spike fully creates a seal. With most infi.lsion containers, this may cause slippery floors and if the contents are toxic, a serious health risk to the practitioner. T'o address this issue, a ported spike is commonly utilized to access the toxic solution in an infusion container so that the toxic drug may be added to the infusion contents through the access port in the spike. However, the prevention of health care provider to toxic material during access of infusion contaillers is not adequately addressed.
SUMMARY OF THE INVENTION
In an embodiment, a vented infusion access device is provided. The device comprises a housing having an open distal end and a forward end, the projecting forward open end terminating as a spike, the spike capable of accessing an infusion container. An access lumen, a delivery lumen, and a vent lumen are located within the spike and each of the lumens provides an opening in proximity to the terminus of the spike. A
connector means is positioned on the housing, the connector means and the access 5 lumen provide a first fluid path. The delivery lumen and the open distal end provide a second fluid path. A check valve is positioned on the housing; the check valve and the vent lumen provide a third fluid pat11. The first fluid path, the second fluid path, and the third fluid path are each isolated from each other.
In another embodiment, a method of delivering toxic material to and/or accessing toxic material fi-om an infusion container is also provided. The method comprises providing a toxic material to be delivered to or accessed from an infilsion container and providing a vented infusion access device. The infusion access device comprises a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion cotitainer. An access lumen, a delivery lumen, apd a vent lumen, are located within the spike, each of the lumens providing an opening in proximity to the terminus of the spike. A connector means is positioned on the housing, the connector means and the access lumen provide a first fluid path. The delivery lumen and the open distal end provide a second fluid path. A
check valve is positioned on the housing, the check valve and the vent lumen provide a third fluid patli, where the first fluid path, the second fluid path, and the third fluid path are each isolated from each other. Penetrating the infusion container with the spike provides that the openings of the lumens be within the infusion container.
Delivering the toxic material to and/or accessing the toxic material from the infusion container with the access lumen and/or the delivery lumen are provided.
BRIEF DE'SCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view of an infusion access device embodiment of the invention.
FIG. 2 is another perspective view of the infusion access device embodiment of FIG.
1.
BACKGROUND OF THE INVENTION
Field of the Invention The present invention relates to a device for accessing an infusioneontainer, which may contain a toxic material, comprising a vented infusion access device for connection to the infusioari container. The device is provided with a spike for connection with the infusion container, the spike comprising at least two lumens for accessing, delivering a fluid, and venting.
Within the medical industry, medical persoluiel may be required to handle cytotoxic drugs, sometimes on a daily basis. A class of cytotoxic drugs is cytostatic chemotherapy agents. It is genet=a11y believed that cytostatics and some antibiotics may cause health problems if inhaled or exposed to the skin. Exposure or inhalation may be through leakage, aerosolization, or vaporization into the working environment during handling of the cytostatics.
When administering a drug via an infusion set, it is a common practice to use a spike to access the contents of the infusion container. In many cases, wlhen the spike piei-ces the septum of the infusion container, fluid leaks before the spike fully creates a seal. With most infi.lsion containers, this may cause slippery floors and if the contents are toxic, a serious health risk to the practitioner. T'o address this issue, a ported spike is commonly utilized to access the toxic solution in an infusion container so that the toxic drug may be added to the infusion contents through the access port in the spike. However, the prevention of health care provider to toxic material during access of infusion contaillers is not adequately addressed.
SUMMARY OF THE INVENTION
In an embodiment, a vented infusion access device is provided. The device comprises a housing having an open distal end and a forward end, the projecting forward open end terminating as a spike, the spike capable of accessing an infusion container. An access lumen, a delivery lumen, and a vent lumen are located within the spike and each of the lumens provides an opening in proximity to the terminus of the spike. A
connector means is positioned on the housing, the connector means and the access 5 lumen provide a first fluid path. The delivery lumen and the open distal end provide a second fluid path. A check valve is positioned on the housing; the check valve and the vent lumen provide a third fluid pat11. The first fluid path, the second fluid path, and the third fluid path are each isolated from each other.
In another embodiment, a method of delivering toxic material to and/or accessing toxic material fi-om an infusion container is also provided. The method comprises providing a toxic material to be delivered to or accessed from an infilsion container and providing a vented infusion access device. The infusion access device comprises a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion cotitainer. An access lumen, a delivery lumen, apd a vent lumen, are located within the spike, each of the lumens providing an opening in proximity to the terminus of the spike. A connector means is positioned on the housing, the connector means and the access lumen provide a first fluid path. The delivery lumen and the open distal end provide a second fluid path. A
check valve is positioned on the housing, the check valve and the vent lumen provide a third fluid patli, where the first fluid path, the second fluid path, and the third fluid path are each isolated from each other. Penetrating the infusion container with the spike provides that the openings of the lumens be within the infusion container.
Delivering the toxic material to and/or accessing the toxic material from the infusion container with the access lumen and/or the delivery lumen are provided.
BRIEF DE'SCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view of an infusion access device embodiment of the invention.
FIG. 2 is another perspective view of the infusion access device embodiment of FIG.
1.
FIG. 3 is a cross-sectional view of the infusion access device einbodiment of FIG. 1. FIG. 4 is a perspective view of an infusion access device embodiment of the invention.
FIG. 5 is a cross-sectional view of the infusion access device embodiment of FIG. 4.
FIG. 6 is a perspective view of an infusion access device embodiment of the invention. FIG. 7 is a cross-sectional view of the infusion access device embodiment of FIG. 6.
FIG. 8 is another cross-sectional view of the infiision access device embodiment of FIG. 6.
FIG. 9 is a perspective view of the infusion access device enibodiment of FIG.
6with-an attached needle-free female valve and check valve vent.
DETAILED DESCRIPTION
A vented infusion access device is provided. for connection and accessing the contents of an infusion container, d1e access device preventing or eliminating exposure of the drnig with the environment.
The vented infusion access device herein disclosed provides a solution for infusion bags and bottles intended for delivering hazardous drug. The vented infusion access device is first inserted into the infusion container prior to adding the drug, for example, in concentrated form, providing for the safe handling of the hazardous drug.
While some fluid may leak out of the infusion container when the infusion container septutn is pierced, the infusion fluid without the drug present is generally non-toxic.
Hazardous drugs may then be added to the infusion bag or bottle through the needle-free valve of the vented infusion access device while preventing or eliminating expostu=e to the hazardous drug. After the toxic drug is mixed into the infusion eontainer, a second device, such as an I. V. administration set (infiision kit), maybe inserted into the distal end of the housing of the vetited infusion access device. Before the second device pierces the membrane inside the vented infusion access device's housing, an annular sealing ring at the entrance of the vented infusion access device distal end provides sealing engagement of the second device. Thus, when the vented infiision access device handle immbrane is pierced, hazardous fluid remains contained inside the housing of the vented infusion access device.
In one enlboditnent, the vented infusion access device includes a spike comprising two hunens, a delivery lumen for flow to the patient and an access lumen for adding drug to the infusion container as well as venting for providing higher flow out of the inftlsion container (particularly in the case of a non-collapsible infusion bottle). The access lumen tnay be in fluid communication with a hydrophobic filter membrane and check valve assembly to allow for the replacement of drug with air inside the infusion conta.iner as the drug is delivered to the patient. The two lumens provide for two isolated fluid flow paths within the device.
In another embodiment, the vented infusion access device includes a spike comprising three lulnens. The lumens includc a delivery lumen for flow to the patient, an access lumen for adding drug to the infusion container, and a vent hunen with inline check valve and optional filter. The vent lumcn separates the hydrophobic filter/check valve port from the connector .means/access lumen fluid path in order to ensure that any spike in pressure generated by injecting drug into the access lumen through the female needle-free valve port is not directly felt by the valve/filter, possibly causing the hydrophobic filter and check valve to become over-pressured and leak. The three lumens provide for three isolated fluid flow paths within the device.
The terin "fluid" as used herein, refers to gas, liquid or a combination of gas and liquid.
FIG. 5 is a cross-sectional view of the infusion access device embodiment of FIG. 4.
FIG. 6 is a perspective view of an infusion access device embodiment of the invention. FIG. 7 is a cross-sectional view of the infusion access device embodiment of FIG. 6.
FIG. 8 is another cross-sectional view of the infiision access device embodiment of FIG. 6.
FIG. 9 is a perspective view of the infusion access device enibodiment of FIG.
6with-an attached needle-free female valve and check valve vent.
DETAILED DESCRIPTION
A vented infusion access device is provided. for connection and accessing the contents of an infusion container, d1e access device preventing or eliminating exposure of the drnig with the environment.
The vented infusion access device herein disclosed provides a solution for infusion bags and bottles intended for delivering hazardous drug. The vented infusion access device is first inserted into the infusion container prior to adding the drug, for example, in concentrated form, providing for the safe handling of the hazardous drug.
While some fluid may leak out of the infusion container when the infusion container septutn is pierced, the infusion fluid without the drug present is generally non-toxic.
Hazardous drugs may then be added to the infusion bag or bottle through the needle-free valve of the vented infusion access device while preventing or eliminating expostu=e to the hazardous drug. After the toxic drug is mixed into the infusion eontainer, a second device, such as an I. V. administration set (infiision kit), maybe inserted into the distal end of the housing of the vetited infusion access device. Before the second device pierces the membrane inside the vented infusion access device's housing, an annular sealing ring at the entrance of the vented infusion access device distal end provides sealing engagement of the second device. Thus, when the vented infiision access device handle immbrane is pierced, hazardous fluid remains contained inside the housing of the vented infusion access device.
In one enlboditnent, the vented infusion access device includes a spike comprising two hunens, a delivery lumen for flow to the patient and an access lumen for adding drug to the infusion container as well as venting for providing higher flow out of the inftlsion container (particularly in the case of a non-collapsible infusion bottle). The access lumen tnay be in fluid communication with a hydrophobic filter membrane and check valve assembly to allow for the replacement of drug with air inside the infusion conta.iner as the drug is delivered to the patient. The two lumens provide for two isolated fluid flow paths within the device.
In another embodiment, the vented infusion access device includes a spike comprising three lulnens. The lumens includc a delivery lumen for flow to the patient, an access lumen for adding drug to the infusion container, and a vent hunen with inline check valve and optional filter. The vent lumcn separates the hydrophobic filter/check valve port from the connector .means/access lumen fluid path in order to ensure that any spike in pressure generated by injecting drug into the access lumen through the female needle-free valve port is not directly felt by the valve/filter, possibly causing the hydrophobic filter and check valve to become over-pressured and leak. The three lumens provide for three isolated fluid flow paths within the device.
The terin "fluid" as used herein, refers to gas, liquid or a combination of gas and liquid.
The term "infusion container" refers to a fluid container such as an I.V. bag, I.V.
bottle, blood bag, and the like. "Infusion container" includes containers for intrathecal administration of fluid.
The term "infusion connector" refers to a device for accessing an infusion container and includes, for example, spikes, blunt cannula, male luers, arid female luers.
A vented infusion access device is provided which comprises a housing. The housing may be of plastic cotlstruction or may be fabricated out of one or more materials designed to withstand chemical attack from substances, such as cytotoxic drugs and other hazardous materials. Materials include for example, thermoplastics, engineering therrnoplastics, filled or unfilled, and composites. Therrnoplastics include materials such as acrylonitrile butadiene styrene (ABS), polybutylene terephthalate (PBT), polyethylene terephthalate (PET) polyethylenenaphthalate (PEN), high impact polystyrene (HIPS), cyclic olefinic copolymers (COC's) and polycarbonate (PC) The housing incorporates a vented and unidirectioiial flow port via a hydrophobic frlter media and check-valve assembly. The vent only allows frltered air int.o the system to replace drug removed from the irlfusion container, which may result in a higher flow rate. This is particularly usefi.zl when using infusion bottles as opposed to bags.
The housing of the device includes a forward end, which ternlinates as a spike. The spike may be integral to the housing and provide for an opening for communicating with the drug container. The spike rnay include at least two lumens both of which nlay be open proximal to the distal end of the spike and function independently of each other. The openings in the lumens may be at the distal end of the spike, the side of the spike or one lurnen opening may be at the distal end of the spike and another lumen opening may be on the side of the spike. The relative positions of the openings of the lumens proximal to the distal end of the spike may be the same or different.
The spike may be constructed of plastic, metal or composite material. The spike may be designed such that it easily pierces the closure of the infusion container.
The open end of the spike may be pointed and/or beveled for facile inser-tion into a closure or other access member of an infusion container.
bottle, blood bag, and the like. "Infusion container" includes containers for intrathecal administration of fluid.
The term "infusion connector" refers to a device for accessing an infusion container and includes, for example, spikes, blunt cannula, male luers, arid female luers.
A vented infusion access device is provided which comprises a housing. The housing may be of plastic cotlstruction or may be fabricated out of one or more materials designed to withstand chemical attack from substances, such as cytotoxic drugs and other hazardous materials. Materials include for example, thermoplastics, engineering therrnoplastics, filled or unfilled, and composites. Therrnoplastics include materials such as acrylonitrile butadiene styrene (ABS), polybutylene terephthalate (PBT), polyethylene terephthalate (PET) polyethylenenaphthalate (PEN), high impact polystyrene (HIPS), cyclic olefinic copolymers (COC's) and polycarbonate (PC) The housing incorporates a vented and unidirectioiial flow port via a hydrophobic frlter media and check-valve assembly. The vent only allows frltered air int.o the system to replace drug removed from the irlfusion container, which may result in a higher flow rate. This is particularly usefi.zl when using infusion bottles as opposed to bags.
The housing of the device includes a forward end, which ternlinates as a spike. The spike may be integral to the housing and provide for an opening for communicating with the drug container. The spike rnay include at least two lumens both of which nlay be open proximal to the distal end of the spike and function independently of each other. The openings in the lumens may be at the distal end of the spike, the side of the spike or one lurnen opening may be at the distal end of the spike and another lumen opening may be on the side of the spike. The relative positions of the openings of the lumens proximal to the distal end of the spike may be the same or different.
The spike may be constructed of plastic, metal or composite material. The spike may be designed such that it easily pierces the closure of the infusion container.
The open end of the spike may be pointed and/or beveled for facile inser-tion into a closure or other access member of an infusion container.
The lumens of the spike provide for multiple fluid paths. At least one of the :fluid paths provides for one-way communication with the atmosphere. One-way fluid communication may be achieved by any means capable of restricting fluid flow, such as a check valve. The fluid path may be in communication with a check valve disposed in cooperating relation with one of the lumens for providing one-way flow of air into the device and infusion container while preventing escape of hazardous material. 10 'l'he check valves preferably have a low cracking pressure so as to prevent or eliminate pressure to build up during use of the device. The cracking pressure preferably is less than 2 psi, less than I psi, or less than 0.5 psi. The check valve ma.y also have a low reverse leakage characteristic to prevent hazardous media from being released into the environlnetit. Check valves include, for example, "duck bill" type or "umbrella" type. Various other types of check valves may be used, for example "top hat", "double duck bill", "umbrella", "flat disc", etc. The use of a check valve filter may significantly improve the flow rate through the vented infusion access device, for example, when used with glass infiision bottles. Without a vent, air must be pulled into the bottle to displace the fluid through the same lumen that the fluid is exiting.
This causes a significant decrease in flow rate and increases the time needed to deliver the drug to a patient. By way of example, the 3 lumen design herein disclosed, utilizes a vent lumen that is separated from the injection port and its flow path, decreasing the possibility of thc hydrophobic filter/check valve assembly being over pressured upon injection of the drug into the bag.
The communication between the fluid path and the check valve may be filtered to avoid contamination of the contents of the drug container. In this arrangement, the contents of infusion container may be accessed and/or withdrawn under uncontaminated atlnospheric pressure conditions. A filter may be disposed in cooperating relation with the check valve. The filters may be sized commensurate with the overall size of the device or its components. The filter may be of a disk-type or any other size sized to fit cooperatively with a check valve. The disk filter may have a hydrophobic surface on one side or on both sides of the disk. The filter may contain a small pore size, such as 1.0, 0.5, 0.4, 0.3, 0.2, or 0.1 micron, however, larger or smaller pore sizes may be used. The venting filter may include the hydrophobic surfacc in eommunication with a fluid path of the spike and surrounding areas to prevent wetting of the filter media, assuring adequate ability to equalize pressure during use of the device. Multiple filters may be used. The selection of filter type and size may be readily determined to provide, adequate surface area and to effectively vent the device quickly under normal use.
The housing includes connector means for accessing the infusion container via at least one of the fluid paths of the spike. The conziector means may provide two-way communication with the fluid paths and lumens of the spike. While in sealable communication with an infusion container, the connector means provides for introduction or withdrawal of fluid using a syringe or other device fiom the infusion container. The fluid communication between the coiulector means aiid the fluid patlis or lumens may be filtered. The connector means may include a check valve to only allow one-way introduction of fluids into the infusion containcr. The connector means inay be mounted on the housing to provide a sealed septuin or similarly constructed valve capable of receiving a device for introduction of fluid to the infusion container. The device for introduction may be a needle, a spike, a blunt camiula, a male luer connector, or similar device. The connector means may comprise a septum containing connector penetrable by ileedles, cannula, blunt needles or spikes, for exaniple. By way of example, coiznector means include a needle-free adapter, a pre-slit septum, or apenetrable septum. The needle-free adapter may be a female luer-activated two-way adapter or male luer adapter. The needle-free adapter may be secured to the housing. Various needle-free adapters as are known in the art ai-e adaptable to the vented infusion access device housing, such as CLAVE
R~', SMARTSITEN, POSIFLOW 1z , BIONECTOROO , and CLEARLINK.CR and others.
The needle-free adapters in combination with the infiision access device herein described provides for accessing the infusion container for introduction and/or withdrawal of fluid through the closure of the infusion container. Hence, elimination or reduction of exposure to hazardous material incident to access and/or withdrawal as the needle-free adapter self-seals is reduced or eliminated and further provides for needle-free manipulation. The coniieetor means preferably is compatible with most syringes and other male luer devices that are readily available. Female needle-free valves may be directly integrated into the housing, potentially eliminating a component alid simplifying manufacturing.
The housing may consist of a handle. The handle may include ergonoinic features for facilitating a secure grip by the user. The housing may be one-piece or of multi-piece construction. Means for assembling the housing may be provided, such as tnating snap-fit features or interference elements.
The housing may include a pre-access seal, such as an internal annular ring at the distal end. The pre-access seal lnay provide for an interference fit with a mating infusion connector.
The housing may include a membrane. The tnembrane may be positioned between the open distal end and the forward end of the housing. The membrane may provide prevention or climination of leaks prior to a secondary device, such as an infusion spike, piercing the membrane.
The housing nlay include an integrated cap positioned at the distal end of the housing.
The cap may prevent or eliminate touch contamination at the housing distal end and/or keep it covered until, for exaniple, an infusion set may be mated with the housing distal end. With the use of the pre-access seal at the housing distal end together with a living hinged cover, the likelihood of toxic fluid in the system being leaked to the environment is reduced or eliminated. In conjunction with the check.
valve filter and a female needle-free valve connected to the female luer port of the device hereiii diselosed, toxic fluids escaping into the enviroiunent is reduced or elim inated.
Referring now to the drawings, various illustrative cmbodiments will be described. FIG.
1 depicts an embodiment of the device herein disclosed consisting of an access lumen 101 for flow out of the infusion container (e.g., bag or bottle) and a connector means (e.g., female port) 102 on the housing 111 that provides for the addition of dnig into the infusion container by way of delivery lumen 105. The handle 112 has textured grip areas 103 and a cap 104 comlected to the housing via living hinge 119 so as to eliminate or prevent touch contamination before use. The handle may be securely attached to the housing with internal ramp features 114. Cap 104 reversibly bends at living hinge 119 connected to handle 212.
FIG. 2 depicts another view of the aforementioried embodiment, showing the delivery lumen 105 for injecting drugs froni the needle-free valve (not shown) through the spike into an infusion container. Cap 104 may contain vents 113 for sterilization.
FIG. 3 depicts a cross section of the aforementioned embodii.llent, showing delivery lumen 105 and access lumen 101 flow paths, respectively. Penetrable membrane is positioned inside the housing between the distal end and forward end of the housing. Tapet=ed area 107 provides for sealably receiving a secondary penetrable device. Annular interference 11.0 creates a seal between handle 112 and the housing 15 111. Annular area 115 may provide means for securely aCtaching handle 112 to housing 111.. An adhesive or other securing agent may be used at annular interference l 10 to provide a securing means.
FIG. 4 depicts vented iiifiision access device 200. Venting port 208 is provided in fluid communication witli access lumen 205. Connector means 202, in fluid communication with access lumen 205, may be used to add drug to the infusion container. FIG. 5 depicts a section view of the device 200 wherein channe1209 provides fluid communication between both the connection means 202 and the venting port 208.
Penetrable iuembrane 206 is positioned inside the housing between the distal end and forward end of the housing. Annular interference 210 creates a seal between handle 212 and the housing 211. Annular area 215 may provide means for securcly attaching handle 212 to housing 211. Access lumen 205 and connector means 202 define a first fluid path. Delivery lumen 201 and penetrable membrane 206 define a second fluid path. The first fluid path and the second fluid path are isolated from each other.
This causes a significant decrease in flow rate and increases the time needed to deliver the drug to a patient. By way of example, the 3 lumen design herein disclosed, utilizes a vent lumen that is separated from the injection port and its flow path, decreasing the possibility of thc hydrophobic filter/check valve assembly being over pressured upon injection of the drug into the bag.
The communication between the fluid path and the check valve may be filtered to avoid contamination of the contents of the drug container. In this arrangement, the contents of infusion container may be accessed and/or withdrawn under uncontaminated atlnospheric pressure conditions. A filter may be disposed in cooperating relation with the check valve. The filters may be sized commensurate with the overall size of the device or its components. The filter may be of a disk-type or any other size sized to fit cooperatively with a check valve. The disk filter may have a hydrophobic surface on one side or on both sides of the disk. The filter may contain a small pore size, such as 1.0, 0.5, 0.4, 0.3, 0.2, or 0.1 micron, however, larger or smaller pore sizes may be used. The venting filter may include the hydrophobic surfacc in eommunication with a fluid path of the spike and surrounding areas to prevent wetting of the filter media, assuring adequate ability to equalize pressure during use of the device. Multiple filters may be used. The selection of filter type and size may be readily determined to provide, adequate surface area and to effectively vent the device quickly under normal use.
The housing includes connector means for accessing the infusion container via at least one of the fluid paths of the spike. The conziector means may provide two-way communication with the fluid paths and lumens of the spike. While in sealable communication with an infusion container, the connector means provides for introduction or withdrawal of fluid using a syringe or other device fiom the infusion container. The fluid communication between the coiulector means aiid the fluid patlis or lumens may be filtered. The connector means may include a check valve to only allow one-way introduction of fluids into the infusion containcr. The connector means inay be mounted on the housing to provide a sealed septuin or similarly constructed valve capable of receiving a device for introduction of fluid to the infusion container. The device for introduction may be a needle, a spike, a blunt camiula, a male luer connector, or similar device. The connector means may comprise a septum containing connector penetrable by ileedles, cannula, blunt needles or spikes, for exaniple. By way of example, coiznector means include a needle-free adapter, a pre-slit septum, or apenetrable septum. The needle-free adapter may be a female luer-activated two-way adapter or male luer adapter. The needle-free adapter may be secured to the housing. Various needle-free adapters as are known in the art ai-e adaptable to the vented infusion access device housing, such as CLAVE
R~', SMARTSITEN, POSIFLOW 1z , BIONECTOROO , and CLEARLINK.CR and others.
The needle-free adapters in combination with the infiision access device herein described provides for accessing the infusion container for introduction and/or withdrawal of fluid through the closure of the infusion container. Hence, elimination or reduction of exposure to hazardous material incident to access and/or withdrawal as the needle-free adapter self-seals is reduced or eliminated and further provides for needle-free manipulation. The coniieetor means preferably is compatible with most syringes and other male luer devices that are readily available. Female needle-free valves may be directly integrated into the housing, potentially eliminating a component alid simplifying manufacturing.
The housing may consist of a handle. The handle may include ergonoinic features for facilitating a secure grip by the user. The housing may be one-piece or of multi-piece construction. Means for assembling the housing may be provided, such as tnating snap-fit features or interference elements.
The housing may include a pre-access seal, such as an internal annular ring at the distal end. The pre-access seal lnay provide for an interference fit with a mating infusion connector.
The housing may include a membrane. The tnembrane may be positioned between the open distal end and the forward end of the housing. The membrane may provide prevention or climination of leaks prior to a secondary device, such as an infusion spike, piercing the membrane.
The housing nlay include an integrated cap positioned at the distal end of the housing.
The cap may prevent or eliminate touch contamination at the housing distal end and/or keep it covered until, for exaniple, an infusion set may be mated with the housing distal end. With the use of the pre-access seal at the housing distal end together with a living hinged cover, the likelihood of toxic fluid in the system being leaked to the environment is reduced or eliminated. In conjunction with the check.
valve filter and a female needle-free valve connected to the female luer port of the device hereiii diselosed, toxic fluids escaping into the enviroiunent is reduced or elim inated.
Referring now to the drawings, various illustrative cmbodiments will be described. FIG.
1 depicts an embodiment of the device herein disclosed consisting of an access lumen 101 for flow out of the infusion container (e.g., bag or bottle) and a connector means (e.g., female port) 102 on the housing 111 that provides for the addition of dnig into the infusion container by way of delivery lumen 105. The handle 112 has textured grip areas 103 and a cap 104 comlected to the housing via living hinge 119 so as to eliminate or prevent touch contamination before use. The handle may be securely attached to the housing with internal ramp features 114. Cap 104 reversibly bends at living hinge 119 connected to handle 212.
FIG. 2 depicts another view of the aforementioried embodiment, showing the delivery lumen 105 for injecting drugs froni the needle-free valve (not shown) through the spike into an infusion container. Cap 104 may contain vents 113 for sterilization.
FIG. 3 depicts a cross section of the aforementioned embodii.llent, showing delivery lumen 105 and access lumen 101 flow paths, respectively. Penetrable membrane is positioned inside the housing between the distal end and forward end of the housing. Tapet=ed area 107 provides for sealably receiving a secondary penetrable device. Annular interference 11.0 creates a seal between handle 112 and the housing 15 111. Annular area 115 may provide means for securely aCtaching handle 112 to housing 111.. An adhesive or other securing agent may be used at annular interference l 10 to provide a securing means.
FIG. 4 depicts vented iiifiision access device 200. Venting port 208 is provided in fluid communication witli access lumen 205. Connector means 202, in fluid communication with access lumen 205, may be used to add drug to the infusion container. FIG. 5 depicts a section view of the device 200 wherein channe1209 provides fluid communication between both the connection means 202 and the venting port 208.
Penetrable iuembrane 206 is positioned inside the housing between the distal end and forward end of the housing. Annular interference 210 creates a seal between handle 212 and the housing 211. Annular area 215 may provide means for securcly attaching handle 212 to housing 211. Access lumen 205 and connector means 202 define a first fluid path. Delivery lumen 201 and penetrable membrane 206 define a second fluid path. The first fluid path and the second fluid path are isolated from each other.
FIGS. 6 through 8 depict vented infusion access device 300. Delivery lumen 301 provides for de-ug delivery to the patient, access himen 305 for adding dnig to the infusion coaritainer, atZd vent lumen 316 for venting. Hydrophobic filter 325 and check valve 320 are positioned in vent port 308.
Access lumcn 305 and connector means 302 define a first fluid path. Delivery lumen 301 and penetrable membrane 306 define a second fluid path. Vent lumen 316 and vent port 308, inchiding check valve 320, define a third fluid path. The first fluid path, the second fluid path, and the third fluid path are isolated from each other.
Retaining feature 315 on the handle and the retaining ramps 314 on the housing provide for assembly. Cap 304 reversibly bends at living hinge 319 connected to handle 312. Internal taper 317 of the cap pops onto housing distal end taper 318 of handle 312, securing the cap.
FIG. 9 depicts device 300 with a hydrophobic filter/check valve asseinbly 320a integral with housing 311 and a needle-free female valve 321 connected to connector means 302.
When. administrating via infusion with the vented infusion access device as herein disclosed, the vented infusion access device is first connected normally to an infusion container such as a bag or bottle containing an infiision fluid. Upon access by an infusion connector via the open distal end of housing and penetration of the menibrane, the fluid path defined by the penetrable membrane and the delivery lumen thereafter fills with the infusion fluid. An injector (not shown) with a corresponding mating means, which may be loaded with a drug to be administrated to the infilsion container, is connected to the connector means. The iiljector is provided access to the colitents of the infizsion container with adequate venting by the check valve.
Thereafter the injector may be withdrawn with little or no exposure to the contents of the infusion container. The infusion can now be started after mixing the contents of the infusion container and coniiection with the distal end of the vented infusion access device using, for example, an infusion kit.
The vented infusion access device described above will normally be supplied in assembled form or as a kit, and may be sterile. The term "vented infusion access device " as used herein is intended to include within its scope the elements thereof in partially or fully disassembled form. The vented infusion access device or kit may contain a needle-free adapter which may be separate, secured to or permanently affixed to the connector means as desired.
As used llerein, "comprising," "including," "containing," "charaeterized by,"
and gi-ammatical equivalents thereof are inclusive or open-ended terms that do not exclude additional, unrecited elements or method steps. "Comprising" is to be interpreted as including the mot-e restrictive terms "consisting of' and "consisting essentially of."
As used herein, "consisting of' and grammatical equivalents thereof exclude any element, step, or ingredient not specified in the claim.
As used herein, "consisting essentially of' and grammatical equivalents thereof limit the scope of a claim to the specified materials or steps and those that do not materially affect the basic and novel characteristic or characteristics of the elailned invention.
While the invention has been described in detail and with refereilce to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications may be rnade without departing from the spirit and scope of the invention
Access lumcn 305 and connector means 302 define a first fluid path. Delivery lumen 301 and penetrable membrane 306 define a second fluid path. Vent lumen 316 and vent port 308, inchiding check valve 320, define a third fluid path. The first fluid path, the second fluid path, and the third fluid path are isolated from each other.
Retaining feature 315 on the handle and the retaining ramps 314 on the housing provide for assembly. Cap 304 reversibly bends at living hinge 319 connected to handle 312. Internal taper 317 of the cap pops onto housing distal end taper 318 of handle 312, securing the cap.
FIG. 9 depicts device 300 with a hydrophobic filter/check valve asseinbly 320a integral with housing 311 and a needle-free female valve 321 connected to connector means 302.
When. administrating via infusion with the vented infusion access device as herein disclosed, the vented infusion access device is first connected normally to an infusion container such as a bag or bottle containing an infiision fluid. Upon access by an infusion connector via the open distal end of housing and penetration of the menibrane, the fluid path defined by the penetrable membrane and the delivery lumen thereafter fills with the infusion fluid. An injector (not shown) with a corresponding mating means, which may be loaded with a drug to be administrated to the infilsion container, is connected to the connector means. The iiljector is provided access to the colitents of the infizsion container with adequate venting by the check valve.
Thereafter the injector may be withdrawn with little or no exposure to the contents of the infusion container. The infusion can now be started after mixing the contents of the infusion container and coniiection with the distal end of the vented infusion access device using, for example, an infusion kit.
The vented infusion access device described above will normally be supplied in assembled form or as a kit, and may be sterile. The term "vented infusion access device " as used herein is intended to include within its scope the elements thereof in partially or fully disassembled form. The vented infusion access device or kit may contain a needle-free adapter which may be separate, secured to or permanently affixed to the connector means as desired.
As used llerein, "comprising," "including," "containing," "charaeterized by,"
and gi-ammatical equivalents thereof are inclusive or open-ended terms that do not exclude additional, unrecited elements or method steps. "Comprising" is to be interpreted as including the mot-e restrictive terms "consisting of' and "consisting essentially of."
As used herein, "consisting of' and grammatical equivalents thereof exclude any element, step, or ingredient not specified in the claim.
As used herein, "consisting essentially of' and grammatical equivalents thereof limit the scope of a claim to the specified materials or steps and those that do not materially affect the basic and novel characteristic or characteristics of the elailned invention.
While the invention has been described in detail and with refereilce to specific embodiments thereof, it will be apparent to one skilled in the art that various changes and modifications may be rnade without departing from the spirit and scope of the invention
Claims (20)
1. A vented infusion access device comprising;
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen, a delivery lumen, and a vent lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path;
a second fluid path comprising the delivery lumen and the open distal end; and a check valve positioned on the housing, the check valve and the vent lumen providing a third fluid path;
wherein the first fluid path, the second fluid path, and the third fluid path are each isolated from each other.
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen, a delivery lumen, and a vent lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path;
a second fluid path comprising the delivery lumen and the open distal end; and a check valve positioned on the housing, the check valve and the vent lumen providing a third fluid path;
wherein the first fluid path, the second fluid path, and the third fluid path are each isolated from each other.
2. The device of claim 1, further comprising a penetrable membrane positioned in the housing between the open distal end and the forward end of the housing.
3. The device of claim 1, wherein the connector means is a septum containing connector.
4. The device of claim 1, wherein the connector means is a needle-free valve connector.
5. The device of claim 1, wherein the open distal end is adapted to receive an infusion connector.
6. The device of claim 1, wherein the check valve further comprises a hydrophobic filter.
7. The device of claim 1, further comprising a cap connected at the open distal end, the cap reversibly covering the open distal end.
8. The device of claim 7, wherein the cap is connected at the open distal end.
9. The device of claim 1, further comprising a seal at the distal end of the housing for sealably receiving an infusion connector.
10. A vented infusion access device comprising;
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen and a delivery lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path, the first fluid path being in fluid communication with a check valve positioned on the housing, the check valve providing venting of the first fluid path; and a second fluid path comprising the delivery lumen and the open distal end;
wherein the first fluid path and the second fluid path are each isolated from each other.
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen and a delivery lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path, the first fluid path being in fluid communication with a check valve positioned on the housing, the check valve providing venting of the first fluid path; and a second fluid path comprising the delivery lumen and the open distal end;
wherein the first fluid path and the second fluid path are each isolated from each other.
11. The device of claim 10, further comprising a penetrable membrane positioned in the housing between the open distal end and the forward end of the housing.
12. The device of claim 10, wherein the connector means is a septum containing connector.
13. The device of claim 10, wherein the connector means is a needle-free valve connector.
14. The device of claim 10, wherein the open distal end is adapted to receive an infusion connector.
15. The device of claim 10, wherein the check valve further comprises a hydrophobic filter.
16. The device of claim 10, further comprising a cap connected at the open distal end, the cap reversibly covering the open distal end.
17. The device of claim 16, wherein the cap is connected at the open distal end.
18. The device of claim 10, further comprising a seal at the distal end of the housing for sealably receiving an infusion connector.
19. A method of delivering toxic material to and/or accessing toxic material from an infusion container, the method comprising:
providing a toxic material to be delivered to or accessed from an infusion container;
providing a vented infusion access device comprising:
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen, a delivery lumen, and a vent lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path;
a second fluid path comprising the delivery lumen and the open distal end; and a check valve positioned on the housing, the check valve and the vent lumen providing a third fluid path; wherein the first fluid path, the second fluid path, and the third fluid path are each isolated from each other;
penetrating the infusion container with the spike such that the openings of the lumens are within the infusion container; and delivering the toxic material to and/or accessing the toxic material from the infusion container via the access lumen and/or the delivery lumen.
providing a toxic material to be delivered to or accessed from an infusion container;
providing a vented infusion access device comprising:
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen, a delivery lumen, and a vent lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path;
a second fluid path comprising the delivery lumen and the open distal end; and a check valve positioned on the housing, the check valve and the vent lumen providing a third fluid path; wherein the first fluid path, the second fluid path, and the third fluid path are each isolated from each other;
penetrating the infusion container with the spike such that the openings of the lumens are within the infusion container; and delivering the toxic material to and/or accessing the toxic material from the infusion container via the access lumen and/or the delivery lumen.
20. A method of delivering toxic material to and/or accessing toxic material from an infusion container, the method comprising:
providing a toxic material to be delivered to or accessed from an infusion container;
providing a vented infusion access device comprising:
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen and a delivery lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path, the first fluid path being in fluid communication with a check valve positioned on the housing, the check valve providing venting of the access lumen; and a second fluid path comprising the delivery lumen and the open distal end; wherein the first fluid path and the second fluid path are each isolated from each other;
penetrating the infusion container with the spike such that the openings of the lumens are within the infusion container; and delivering the toxic material to and/or accessing the toxic material from the infusion container via the access lumen and/or the delivery lumen.
providing a toxic material to be delivered to or accessed from an infusion container;
providing a vented infusion access device comprising:
a housing having an open distal end and a forward end, the forward end terminating as a spike, the spike capable of accessing an infusion container;
an access lumen and a delivery lumen, each of said lumens located within the spike, each of said lumens providing an opening in proximity to the terminus of the spike;
a connector means positioned on the housing, the connector means and the access lumen providing a first fluid path, the first fluid path being in fluid communication with a check valve positioned on the housing, the check valve providing venting of the access lumen; and a second fluid path comprising the delivery lumen and the open distal end; wherein the first fluid path and the second fluid path are each isolated from each other;
penetrating the infusion container with the spike such that the openings of the lumens are within the infusion container; and delivering the toxic material to and/or accessing the toxic material from the infusion container via the access lumen and/or the delivery lumen.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79756706P | 2006-05-04 | 2006-05-04 | |
| US60/797,567 | 2006-05-04 | ||
| PCT/US2007/068270 WO2007131183A2 (en) | 2006-05-04 | 2007-05-04 | Vented infusion access device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2650966A1 true CA2650966A1 (en) | 2007-11-15 |
| CA2650966C CA2650966C (en) | 2014-11-18 |
Family
ID=38668591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2650966A Active CA2650966C (en) | 2006-05-04 | 2007-05-04 | Vented infusion access device |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2012862A4 (en) |
| JP (1) | JP5095727B2 (en) |
| CN (1) | CN101478929A (en) |
| AU (1) | AU2007247932A1 (en) |
| CA (1) | CA2650966C (en) |
| SG (1) | SG171637A1 (en) |
| WO (1) | WO2007131183A2 (en) |
| ZA (1) | ZA200809022B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023287389A1 (en) * | 2021-07-15 | 2023-01-19 | Hrynenko Larysa Antonivna | Infusion device |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090305315A1 (en) * | 2008-06-09 | 2009-12-10 | Kent Raphael Gandola | Hubbed dual cannula device for closed container sampling systems |
| ITMO20090027A1 (en) * | 2009-02-06 | 2010-08-07 | Aries S R L | PERFORATOR DEVICE, PARTICULARLY FOR CONTAINERS OF PHYSIOLOGICAL FLUIDS FOR MEDICAL AND SIMILAR USE, AS CONTAINMENT BAGS, BOTTLES AND THE LIKE. |
| CN102985050A (en) * | 2010-07-12 | 2013-03-20 | 株式会社Jms | medical liquid dispenser |
| US9089474B2 (en) * | 2012-07-13 | 2015-07-28 | Becton Dickinson and Company Ltd. | Medical vial access device with pressure equalization and closed drug transfer system and method utilizing same |
| WO2014029673A1 (en) * | 2012-08-20 | 2014-02-27 | B. Braun Melsungen Ag | Drip chamber for infusion appliance with automatic filling |
| CN106456443B (en) * | 2014-05-02 | 2020-03-06 | 株式会社Jms | Connector for medical container and cover for male member |
| BE1023649B1 (en) * | 2015-12-03 | 2017-06-06 | Trasis S.A. | PERFORATING NEEDLE FOR FLASK WITH SEPTUM |
| DE102017205250A1 (en) * | 2017-03-28 | 2018-10-04 | B. Braun Melsungen Ag | Piercing part for a medical infusion system |
| JP6527631B1 (en) * | 2018-12-05 | 2019-06-05 | イーエヌ大塚製薬株式会社 | connector |
| CN111297683B (en) * | 2020-03-20 | 2021-05-07 | 江苏苏云医疗器材有限公司 | Safe type liquid medicine translator |
| CA3198353A1 (en) | 2020-10-09 | 2022-04-14 | Icu Medical, Inc. | Fluid transfer device and method of use for same |
| CN112472916B (en) * | 2020-11-30 | 2022-08-02 | 江苏松泽医疗科技有限公司 | Multi-channel puncture outfit |
| CN113941051B (en) * | 2021-01-06 | 2022-06-17 | 中国人民解放军总医院 | A multi-barrel syringe |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3822700A (en) * | 1973-03-16 | 1974-07-09 | M Pennington | Intravenous solution dispenser |
| US3938520A (en) * | 1974-06-10 | 1976-02-17 | Abbott Laboratories | Transfer unit having a dual channel transfer member |
| US4392850A (en) * | 1981-11-23 | 1983-07-12 | Abbott Laboratories | In-line transfer unit |
| US4834744A (en) * | 1987-11-04 | 1989-05-30 | Critikon, Inc. | Spike for parenteral solution container |
| SE509950C2 (en) * | 1995-05-02 | 1999-03-29 | Carmel Pharma Ab | Device for the administration of toxic liquid |
| US5941848A (en) * | 1996-11-14 | 1999-08-24 | Baxter International Inc. | Passive drug delivery apparatus |
| JP3422367B2 (en) * | 1999-09-27 | 2003-06-30 | 株式会社トップ | Medical device fluid check valve |
| US6685692B2 (en) * | 2001-03-08 | 2004-02-03 | Abbott Laboratories | Drug delivery system |
| US7744581B2 (en) * | 2002-04-08 | 2010-06-29 | Carmel Pharma Ab | Device and method for mixing medical fluids |
| US8122923B2 (en) * | 2003-10-30 | 2012-02-28 | Teva Medical Ltd. | Safety drug handling device |
-
2007
- 2007-05-04 SG SG201103060-8A patent/SG171637A1/en unknown
- 2007-05-04 JP JP2009510103A patent/JP5095727B2/en active Active
- 2007-05-04 CA CA2650966A patent/CA2650966C/en active Active
- 2007-05-04 AU AU2007247932A patent/AU2007247932A1/en not_active Abandoned
- 2007-05-04 WO PCT/US2007/068270 patent/WO2007131183A2/en not_active Ceased
- 2007-05-04 CN CNA2007800161020A patent/CN101478929A/en active Pending
- 2007-05-04 EP EP07761910.4A patent/EP2012862A4/en not_active Withdrawn
-
2008
- 2008-10-21 ZA ZA200809022A patent/ZA200809022B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023287389A1 (en) * | 2021-07-15 | 2023-01-19 | Hrynenko Larysa Antonivna | Infusion device |
Also Published As
| Publication number | Publication date |
|---|---|
| SG171637A1 (en) | 2011-06-29 |
| EP2012862A4 (en) | 2014-06-04 |
| CN101478929A (en) | 2009-07-08 |
| JP2009536085A (en) | 2009-10-08 |
| AU2007247932A1 (en) | 2007-11-15 |
| ZA200809022B (en) | 2009-08-26 |
| WO2007131183A2 (en) | 2007-11-15 |
| CA2650966C (en) | 2014-11-18 |
| WO2007131183A3 (en) | 2008-12-18 |
| EP2012862A2 (en) | 2009-01-14 |
| JP5095727B2 (en) | 2012-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2650966C (en) | Vented infusion access device | |
| JP7356487B2 (en) | Storage device for single or multiple containers | |
| CA2476075C (en) | Device for mixing medical fluids, and method for enabling such mixing | |
| EP1957028B1 (en) | Needleless additive control valve | |
| CA2527924C (en) | Hazardous material handling system and method | |
| US7743799B2 (en) | Vented safe handling vial adapter | |
| US8156971B2 (en) | Method and apparatus for the handling of a hazardous fluid | |
| EP3626302B1 (en) | System for closed transfer of fluids with a locking member | |
| EP2999631B1 (en) | Vial and syringe adaptors and systems using same | |
| JP5685522B2 (en) | Duplex container fluid transfer device | |
| JP4973661B2 (en) | Chemical solution preparation kit | |
| ES2682352T3 (en) | Cannula Seal System | |
| US20250090424A1 (en) | Transfer device for use with infusion liquid container | |
| CN113301882B (en) | Reconstitution system for drug administration via high vacuum vials with integrated ventilation catheter | |
| US20070016161A1 (en) | Controlled flow adapter with piercing end for medical fluid containers | |
| EP3107600B1 (en) | Aspirating valve device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |