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CA2575860A1 - System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea - Google Patents

System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea Download PDF

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Publication number
CA2575860A1
CA2575860A1 CA002575860A CA2575860A CA2575860A1 CA 2575860 A1 CA2575860 A1 CA 2575860A1 CA 002575860 A CA002575860 A CA 002575860A CA 2575860 A CA2575860 A CA 2575860A CA 2575860 A1 CA2575860 A1 CA 2575860A1
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Canada
Prior art keywords
patient
data values
flow
airway
index
Prior art date
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Granted
Application number
CA002575860A
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French (fr)
Other versions
CA2575860C (en
Inventor
David M. Rapoport
Roger A. Gruenke
Robert G. Norman
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Puritan Bennett Corp
New York University NYU
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/246,964 external-priority patent/US5490502A/en
Application filed by Individual filed Critical Individual
Publication of CA2575860A1 publication Critical patent/CA2575860A1/en
Application granted granted Critical
Publication of CA2575860C publication Critical patent/CA2575860C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

In the treatment of obstructive sleep apnea, a method and apparatus (70) are disclosed for optimizing the controlled positive pressure to minimize the flow of air from a flow generator (86) while still ensuring that flow limitation in the patient's airway doest not occur. In particular, the invention relates to a breathing device (70) and method of use to adjust a controlled positive pressure to the airway of a patient by detecting flow limitation from analysis of an inspiratory flow waveform.
Once the presence of flow limitation has been analyzed the system determined an action to take for adjustment of the controlled positive pressure. The pressure setting is raised, lowered or maintained depending on whether flow limitation has been detected and on the previous actions taken by the system. The preferred breathing apparatus (70) consists of a flow generator (86), a flow sensor (72), an analog to digital converter (78), a microprocessor (80), and a pressure controller (82, 84), a patient supply hose (74), a nasal fitting, and, optionally, a pressure transducer (90). Using the method of the present invention, the microprocessor (80) adjusts the air pressure in the patient's supply hose (74) when flow limitation is detected in the airway of the patient.

Claims (14)

1. A method for detecting flow limitations in the airway of a patient, comprising the steps of:
a) providing a nasal fitting in fluid communication with the airway of a patient, the nasal fitting having means for measuring the inspiratory flow of ambient air to the patient;
b) detecting the onset of an inspiratory flow of air to the airway of the patient;

c) storing data values representative of the inspiratory flow of breathing gas to the patient; and d) determining whether the stored data values indicate a flow limitation in the patient.
2. The method of claim 1, further comprising the steps of measuring the expiratory flow of ambient air from the patient, and storing second data values representative of the expiratory flow.
3. The method of claim 1, further comprising the step of prescribing a regime of patient treatment when the stored data values indicate a flow limitation in the airway of the patient.
4. The method of claim 1, further comprising the steps of:
e) repeating steps b) through d) for a plurality of patient inspirations to create a plurality of peak flow values for flow limited breaths and to create a plurality of peak flow values for non-flow limited breaths;
f) correlating the stored data values with a pure sine wave to create a first index;
g) comparing a regression fit of the stored data values with a regression fit of a pure sine wave to create a second index;
h) comparing a peak value of the stored data values with a peak value of a derivative of the stored data values to create a third index; and i) comparing a peak value of the stored data values with an average of the plurality of peak flow values for flow limited breaths and with an average of the plurality of peak flow values for non-flow limited breaths to create a fourth index.
5. The method of claim 4, further comprising the step of calculating a fifth index as a mathematical function of the first index, the second index, the third index and the fourth index, wherein each index includes a weighted coefficient having a range including a value of zero.
6. A breathing device for detecting flow limitation in the airway of a patient, comprising:
a nasal fitting in fluid communication with the airway of a patient, said nasal fitting having an inlet and a flow restrictor positioned between the inlet and the airway of the patient;

a flow sensor in fluid communication with said nasal fitting and configured to generate first data values representative of an inspiratory flow of ambient air to the patient;
a microprocessor configured to determine whether the first data values indicate a flow limitation in the patient and to generate second data values representative of a flow limitation; and computer memory configured to store the first data values generated by said flow sensor and the second data values generated by said microprocessor.
7. The breathing device of claim 6, further comprising a position sensor configured to generate third data values representative of the physical position of the patient, wherein said computer memory is further configured to store the third data values.
8. The breathing device of claim 6, further comprising an oximeter configured to generate fourth data values representative of the oxyhemoglobin saturation level of the blood of the patient, wherein said computer memory is further configured to store the fourth data values.
9. The breathing device of claim 6, wherein said flow sensor is further configured to generate fifth data values representative of an expiratory flow of ambient air from the patient, and said computer memory is further configured to store the fifth data values.
10. The breathing device of claim 6, wherein said microprocessor includes processing means for correlating the stored data values with a sinusoidal contour, analyzing the stored data values for flatness, analyzing the stored data values for respiratory effort, and analyzing the stored data values for relative flow magnitude.
11. A method for diagnosing a patient having obstructive sleep apnea, comprising the steps of:
providing a patient with a diagnostic breathing device for use at the home of a patient while the patient is asleep;
storing first data values representative of the inspiratory flow of air to the airway of the patient while the patient is using the diagnostic breathing device;
analyzing the first data values to determine the presence of flow limitation in the airway of the patient;
providing the patient with a self-adjusting therapy breathing device for use at the home of a patient while the patient is asleep;

storing second data values representative of the inspiratory flow of air to the airway of the patient and third data values representative of the pressure in the airway of the patient while the patient is using the self-adjusting therapy breathing device;
analyzing the second data values to determine the amount of flow limitation in the airway of the patient; and providing, when the third data values indicate large pressure fluctuations, a self-adjusting therapy breathing device to the patient for use at home while sleeping.
12. The method of claim 11, further comprising the step of providing, when the third data values do not indicate large pressure fluctuations, a constant positive airway pressure breathing device to the patient for use at home while sleeping.
13. The method of claim 11, further comprising the step of referring the patient to a sleep lab when the first data values do not indicate that a flow limitation was present in the patient.
14. The method of claim 11, further comprising the step of referring the patient to a sleep lab when the second data values and the third data values do not indicate that the patient was restored to normal breathing.
CA2575860A 1994-05-20 1995-05-16 System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea Expired - Lifetime CA2575860C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/246,964 1994-05-20
US08/246,964 US5490502A (en) 1992-05-07 1994-05-20 Method and apparatus for optimizing the continuous positive airway pressure for treating obstructive sleep apnea
CA002190488A CA2190488C (en) 1994-05-20 1995-05-16 System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002190488A Division CA2190488C (en) 1994-05-20 1995-05-16 System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea

Publications (2)

Publication Number Publication Date
CA2575860A1 true CA2575860A1 (en) 1995-11-30
CA2575860C CA2575860C (en) 2010-07-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2575860A Expired - Lifetime CA2575860C (en) 1994-05-20 1995-05-16 System for optimizing continuous positive airway pressure for treatment of obstructive sleep apnea

Country Status (1)

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CA (1) CA2575860C (en)

Also Published As

Publication number Publication date
CA2575860C (en) 2010-07-20

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