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CA2559998A1 - Rapamycin conjugates and antibodies - Google Patents

Rapamycin conjugates and antibodies Download PDF

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Publication number
CA2559998A1
CA2559998A1 CA002559998A CA2559998A CA2559998A1 CA 2559998 A1 CA2559998 A1 CA 2559998A1 CA 002559998 A CA002559998 A CA 002559998A CA 2559998 A CA2559998 A CA 2559998A CA 2559998 A1 CA2559998 A1 CA 2559998A1
Authority
CA
Canada
Prior art keywords
rapamycin
antibodies specific
antibodies
conjugates
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002559998A
Other languages
French (fr)
Other versions
CA2559998C (en
Inventor
Eduardo Gonzalez
John C. Russell
Katherine L. Molnar-Kimber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Mitel Communications Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from CA002161101A external-priority patent/CA2161101A1/en
Publication of CA2559998A1 publication Critical patent/CA2559998A1/en
Application granted granted Critical
Publication of CA2559998C publication Critical patent/CA2559998C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Provided are rapamycin conjugates which are useful as immunogenic molecules for the generation of antibodies specific for rapamycin or a derivative thereof, for measuring levels of rapamycin or derivatives thereof; for isolating rapamycin binding proteins; and detecting antibodies specific for rapamycin or derivatives thereof. This invention also provides monoclonal antibodies specific for rapamycin or a ring opened derivative of rapamycin.
CA002559998A 1993-04-23 1994-04-22 Rapamycin conjugates and antibodies Expired - Lifetime CA2559998C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US5303093A 1993-04-23 1993-04-23
US08/053,030 1993-04-23
US08/224,205 1994-04-14
US22420594A 1994-04-19 1994-04-19
CA002161101A CA2161101A1 (en) 1993-04-23 1994-04-22 Rapamycin conjugates and antibodies

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002161101A Division CA2161101A1 (en) 1993-04-23 1994-04-22 Rapamycin conjugates and antibodies

Publications (2)

Publication Number Publication Date
CA2559998A1 true CA2559998A1 (en) 1994-11-10
CA2559998C CA2559998C (en) 2009-04-14

Family

ID=37480453

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002559998A Expired - Lifetime CA2559998C (en) 1993-04-23 1994-04-22 Rapamycin conjugates and antibodies

Country Status (1)

Country Link
CA (1) CA2559998C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022272154A3 (en) * 2021-06-25 2023-02-02 Apertor Pharmaceuticals, Inc. Small molecule compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022272154A3 (en) * 2021-06-25 2023-02-02 Apertor Pharmaceuticals, Inc. Small molecule compounds

Also Published As

Publication number Publication date
CA2559998C (en) 2009-04-14

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MKEX Expiry

Effective date: 20140422