CA2509031A1 - Methode de fabrication de reseaux de blocs, et perforateur a tissus et blocs tissulaires utilises - Google Patents
Methode de fabrication de reseaux de blocs, et perforateur a tissus et blocs tissulaires utilises Download PDFInfo
- Publication number
- CA2509031A1 CA2509031A1 CA 2509031 CA2509031A CA2509031A1 CA 2509031 A1 CA2509031 A1 CA 2509031A1 CA 2509031 CA2509031 CA 2509031 CA 2509031 A CA2509031 A CA 2509031A CA 2509031 A1 CA2509031 A1 CA 2509031A1
- Authority
- CA
- Canada
- Prior art keywords
- tissue
- tubular blade
- block
- punching
- array blocks
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004080 punching Methods 0.000 title claims description 94
- 238000000034 method Methods 0.000 title claims description 59
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims abstract description 86
- 239000012188 paraffin wax Substances 0.000 claims abstract description 78
- 210000000056 organ Anatomy 0.000 claims abstract description 77
- 229940057995 liquid paraffin Drugs 0.000 claims abstract description 36
- 238000010438 heat treatment Methods 0.000 claims description 15
- 210000001519 tissue Anatomy 0.000 description 280
- 238000003745 diagnosis Methods 0.000 description 12
- 239000011521 glass Substances 0.000 description 9
- 238000012744 immunostaining Methods 0.000 description 7
- 238000007901 in situ hybridization Methods 0.000 description 7
- 238000010186 staining Methods 0.000 description 7
- 239000002390 adhesive tape Substances 0.000 description 4
- 238000003491 array Methods 0.000 description 4
- 230000001575 pathological effect Effects 0.000 description 4
- 238000001816 cooling Methods 0.000 description 3
- 238000010827 pathological analysis Methods 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000006059 cover glass Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 238000009966 trimming Methods 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
- G01N2001/288—Filter punches
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2509031 CA2509031A1 (fr) | 2005-06-02 | 2005-06-02 | Methode de fabrication de reseaux de blocs, et perforateur a tissus et blocs tissulaires utilises |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2509031 CA2509031A1 (fr) | 2005-06-02 | 2005-06-02 | Methode de fabrication de reseaux de blocs, et perforateur a tissus et blocs tissulaires utilises |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2509031A1 true CA2509031A1 (fr) | 2006-12-02 |
Family
ID=37480364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2509031 Abandoned CA2509031A1 (fr) | 2005-06-02 | 2005-06-02 | Methode de fabrication de reseaux de blocs, et perforateur a tissus et blocs tissulaires utilises |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2509031A1 (fr) |
-
2005
- 2005-06-02 CA CA 2509031 patent/CA2509031A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |