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CA2464660C - Solution d'inhalation a base d'albuterol, et systeme, kit et methode permettant de soulager les symptomes de l'asthme pediatrique - Google Patents

Solution d'inhalation a base d'albuterol, et systeme, kit et methode permettant de soulager les symptomes de l'asthme pediatrique Download PDF

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Publication number
CA2464660C
CA2464660C CA2464660A CA2464660A CA2464660C CA 2464660 C CA2464660 C CA 2464660C CA 2464660 A CA2464660 A CA 2464660A CA 2464660 A CA2464660 A CA 2464660A CA 2464660 C CA2464660 C CA 2464660C
Authority
CA
Canada
Prior art keywords
solution
inhalation solution
albuterol
asthma
inhalation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2464660A
Other languages
English (en)
Other versions
CA2464660A1 (fr
Inventor
Imtiaz Chaudry
Partha Banerjee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mylan Specialty LP
Original Assignee
Dey LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/034,829 external-priority patent/US6702997B2/en
Application filed by Dey LP filed Critical Dey LP
Publication of CA2464660A1 publication Critical patent/CA2464660A1/fr
Application granted granted Critical
Publication of CA2464660C publication Critical patent/CA2464660C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Solution d'inhalation à base d'albutérol, et système, kit et méthode permettant de soulager le bronchospasme chez les enfants souffrant d'asthme. Dans un mode de réalisation, la solution selon la présente invention est une dose unitaire stérile, prémélangée et prémesurée d'albutérol pour des patients asthmatiques ayant de 2 à 12 ans. Cette solution peut être exempte de produits chimiques anti-microbiens tels que le chlorure de benzalconium. Dans un autre mode de réalisation, la solution selon la présente invention contient environ 0,63 mg ou environ 1,25 mg d'albutérol.
CA2464660A 2001-10-26 2002-10-18 Solution d'inhalation a base d'albuterol, et systeme, kit et methode permettant de soulager les symptomes de l'asthme pediatrique Expired - Fee Related CA2464660C (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US34820301P 2001-10-26 2001-10-26
US60/348,203 2001-10-26
US10/034,829 US6702997B2 (en) 2001-10-26 2001-12-27 Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US10/034,829 2001-12-28
AU32975/02A AU3297502A (en) 2001-10-26 2002-04-05 An albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
AU32975/02 2002-04-05
JP2002145456A JP2003212764A (ja) 2001-10-26 2002-04-11 小児喘息の症状を緩和するためのアルブテロール吸入溶液、システム、キット及び方法
JP2002-145456 2002-04-11
PCT/US2002/033352 WO2003037317A1 (fr) 2001-10-26 2002-10-18 Solution d'inhalation a base d'albuterol, et systeme, kit et methode permettant de soulager les symptomes de l'asthme pediatrique

Publications (2)

Publication Number Publication Date
CA2464660A1 CA2464660A1 (fr) 2003-05-08
CA2464660C true CA2464660C (fr) 2011-12-20

Family

ID=27422969

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2464660A Expired - Fee Related CA2464660C (fr) 2001-10-26 2002-10-18 Solution d'inhalation a base d'albuterol, et systeme, kit et methode permettant de soulager les symptomes de l'asthme pediatrique

Country Status (6)

Country Link
EP (1) EP1441709A1 (fr)
JP (1) JP2006513129A (fr)
CA (1) CA2464660C (fr)
MX (1) MXPA04003928A (fr)
NZ (1) NZ550304A (fr)
WO (1) WO2003037317A1 (fr)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62292719A (ja) * 1986-06-12 1987-12-19 Kaken Pharmaceut Co Ltd 外用澄明水溶性製剤
GB8825892D0 (en) * 1988-11-04 1988-12-07 Fisons Plc Pharmaceutical composition
SK280911B6 (sk) * 1992-12-09 2000-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Farmaceutický prostriedok
WO1995021820A1 (fr) * 1994-02-10 1995-08-17 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive du carbamate et composition correspondante
WO1997003068A1 (fr) * 1995-07-11 1997-01-30 Merck & Co., Inc. Sel de bisulfate de triazolymethyle-indole ethylamine
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
AU9674398A (en) * 1997-10-09 1999-05-03 Schering Corporation Mometasone furoate suspensions for nebulization
US20030183224A1 (en) * 2000-03-01 2003-10-02 Hailey Mark Andrew Metered dose inhaler
US6451289B2 (en) * 2000-03-24 2002-09-17 Sepracor Inc. Albuterol formulations

Also Published As

Publication number Publication date
JP2006513129A (ja) 2006-04-20
EP1441709A1 (fr) 2004-08-04
CA2464660A1 (fr) 2003-05-08
NZ550304A (en) 2008-05-30
WO2003037317A1 (fr) 2003-05-08
MXPA04003928A (es) 2005-03-31

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Effective date: 20201019