CA2462646A1 - Compositions de meningocoque assorties d'un adjuvant - Google Patents
Compositions de meningocoque assorties d'un adjuvant Download PDFInfo
- Publication number
- CA2462646A1 CA2462646A1 CA002462646A CA2462646A CA2462646A1 CA 2462646 A1 CA2462646 A1 CA 2462646A1 CA 002462646 A CA002462646 A CA 002462646A CA 2462646 A CA2462646 A CA 2462646A CA 2462646 A1 CA2462646 A1 CA 2462646A1
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6093—Synthetic polymers, e.g. polyethyleneglycol [PEG], Polymers or copolymers of (D) glutamate and (D) lysine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Biological Depolymerization Polymers (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
L'invention concerne une combinaison d'oligonucléotides CpG et de microparticules polymères qui constitue un adjuvant extrêmement efficace pour des antigènes de Neisseria. L'invention concerne donc une composition comprenant (a) un antigène de Neisseria; (b) un oligonucléotide CpG; et (c) une microparticule polymère biodégradable.
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32692901P | 2001-10-03 | 2001-10-03 | |
| US60/326,929 | 2001-10-03 | ||
| PCT/US2002/010869 WO2002080648A2 (fr) | 2001-04-05 | 2002-04-05 | Augmentation de l'immunite des muqueuses a la suite d'un amorçage parenteral |
| USPCT/US02/10869 | 2002-04-05 | ||
| US37354702P | 2002-04-17 | 2002-04-17 | |
| US60/373,547 | 2002-04-17 | ||
| US38067702P | 2002-05-13 | 2002-05-13 | |
| US60/380,677 | 2002-05-13 | ||
| US25443802A | 2002-09-24 | 2002-09-24 | |
| USPCT/US02/30423 | 2002-09-24 | ||
| US0230423 | 2002-09-24 | ||
| US10/254,438 | 2002-09-24 | ||
| USPCT/US02/31486 | 2002-10-03 | ||
| PCT/US2002/031726 WO2003028661A2 (fr) | 2001-10-03 | 2002-10-03 | Compositions de meningocoque assorties d'un adjuvant |
| US10/265,083 | 2002-10-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2462646A1 true CA2462646A1 (fr) | 2003-04-10 |
| CA2462646C CA2462646C (fr) | 2013-02-12 |
Family
ID=32601151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2462646A Expired - Fee Related CA2462646C (fr) | 2001-10-03 | 2002-10-03 | Compositions de meningocoque assorties d'un adjuvant |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1438323A4 (fr) |
| JP (1) | JP4522699B2 (fr) |
| CN (1) | CN100354297C (fr) |
| AU (1) | AU2002334844B2 (fr) |
| BR (1) | BR0213119A (fr) |
| CA (1) | CA2462646C (fr) |
| NZ (1) | NZ532274A (fr) |
| WO (1) | WO2003028661A2 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0302218D0 (en) | 2003-01-30 | 2003-03-05 | Chiron Sri | Vaccine formulation & Mucosal delivery |
| MXPA04011249A (es) * | 2002-05-14 | 2005-06-06 | Chiron Srl | Vacunas mucosales con adyuvante de quitosano y antigenos meningococicos. |
| MY149591A (en) * | 2002-08-02 | 2013-09-13 | Glaxosmithkline Biolog Sa | Vaccines comprising l2 and/or l3 los from neisseria |
| CA2511512C (fr) | 2002-12-27 | 2013-10-29 | Chiron Corporation | Immunogenes contenant des compositions de phospholipide |
| CA2514328C (fr) * | 2003-01-30 | 2020-01-14 | Chiron Srl | Vaccins injectables contre les multiples serogroupes du meningocoque |
| WO2004075829A2 (fr) * | 2003-01-30 | 2004-09-10 | Chiron Corporation | Vaccin contre la grippe contenant un adjuvant |
| US7731967B2 (en) | 2003-04-30 | 2010-06-08 | Novartis Vaccines And Diagnostics, Inc. | Compositions for inducing immune responses |
| DE602004022286D1 (de) | 2003-06-02 | 2009-09-10 | Novartis Vaccines & Diagnostic | Immunogene zusammensetzungen auf basis von biologisch abbaubaren mikroteilchen enthaltend ein diphtherie- und ein tetanustoxoid |
| CA2555105A1 (fr) * | 2004-02-20 | 2005-09-09 | Hybridon, Inc. | Reponse immunitaire mucosale puissante induite par des oligonucleotides immunomodulateurs modifies |
| ES2434029T3 (es) * | 2004-11-15 | 2013-12-13 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunogénicas que contiene antígeno de antrax, micropartículas de polímero biodegradable, y adyuvante inmunológico que contiene polinucleótido |
| AU2006207891C1 (en) | 2005-01-28 | 2011-09-01 | Galen Bio, Inc. | Immunologically active compositions |
| WO2006092607A1 (fr) * | 2005-03-02 | 2006-09-08 | The Secretary Of State For Defence | Composition pharmaceutique |
| EP2244695A1 (fr) | 2007-12-07 | 2010-11-03 | Novartis AG | Compositions utilisées pour induire des réponses immunitaires |
| CN101559225B (zh) * | 2008-04-18 | 2012-07-11 | 北京生物制品研究所 | 脑膜炎球菌疫苗 |
| AU2013278056B2 (en) * | 2012-06-21 | 2018-07-05 | Northwestern University | Peptide conjugated particles |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6239116B1 (en) * | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| BR9813930A (pt) * | 1997-11-06 | 2006-12-19 | Chiron Spa | antìgeno neisserial |
| WO1999036544A2 (fr) * | 1998-01-14 | 1999-07-22 | Chiron S.P.A. | Antigenes du $i(neisseria meningitidis) |
| CN101293920B (zh) * | 1998-05-01 | 2012-07-18 | 诺华疫苗和诊断公司 | 脑膜炎奈瑟球菌抗原和组合物 |
| PT1100468E (pt) * | 1998-07-29 | 2006-07-31 | Chiron Corp | Microparticulas com superficies adsorventes, processos de fabrico e utilizacao das mesmas |
| JP2004511201A (ja) * | 1998-10-09 | 2004-04-15 | カイロン コーポレイション | ナイセリアゲノム配列およびそれらの使用方法 |
| AU2457100A (en) * | 1999-02-26 | 2000-09-14 | Chiron S.P.A. | Enhancement of bactericidal activity of neisseria antigens with oligonucleotidescontaining cg motifs |
| AU2875700A (en) * | 1999-02-26 | 2000-09-14 | Chiron Corporation | Microemulsions with adsorbed macromoelecules and microparticles |
| JP2003518363A (ja) * | 1999-04-30 | 2003-06-10 | カイロン エセ．ピー．アー． | 保存されたナイセリア抗原 |
| CN100339482C (zh) * | 2000-02-28 | 2007-09-26 | 启龙股份公司 | 奈瑟球菌蛋白质的杂交表达 |
-
2002
- 2002-10-03 CN CNB028241282A patent/CN100354297C/zh not_active Expired - Fee Related
- 2002-10-03 WO PCT/US2002/031726 patent/WO2003028661A2/fr active IP Right Grant
- 2002-10-03 BR BR0213119-6A patent/BR0213119A/pt not_active IP Right Cessation
- 2002-10-03 AU AU2002334844A patent/AU2002334844B2/en not_active Ceased
- 2002-10-03 NZ NZ532274A patent/NZ532274A/en not_active IP Right Cessation
- 2002-10-03 JP JP2003531997A patent/JP4522699B2/ja not_active Expired - Fee Related
- 2002-10-03 CA CA2462646A patent/CA2462646C/fr not_active Expired - Fee Related
- 2002-10-03 EP EP02800481A patent/EP1438323A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003028661A3 (fr) | 2003-10-09 |
| CN1599746A (zh) | 2005-03-23 |
| BR0213119A (pt) | 2004-12-28 |
| JP2005526697A (ja) | 2005-09-08 |
| JP4522699B2 (ja) | 2010-08-11 |
| WO2003028661A2 (fr) | 2003-04-10 |
| EP1438323A2 (fr) | 2004-07-21 |
| EP1438323A4 (fr) | 2007-08-01 |
| CN100354297C (zh) | 2007-12-12 |
| NZ532274A (en) | 2006-02-24 |
| CA2462646C (fr) | 2013-02-12 |
| AU2002334844B8 (en) | 2003-04-14 |
| AU2002334844B2 (en) | 2007-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20141003 |