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CA2416201A1 - Bioactive calcium phosphate composite layers electrochemically deposited on implants - Google Patents

Bioactive calcium phosphate composite layers electrochemically deposited on implants Download PDF

Info

Publication number
CA2416201A1
CA2416201A1 CA002416201A CA2416201A CA2416201A1 CA 2416201 A1 CA2416201 A1 CA 2416201A1 CA 002416201 A CA002416201 A CA 002416201A CA 2416201 A CA2416201 A CA 2416201A CA 2416201 A1 CA2416201 A1 CA 2416201A1
Authority
CA
Canada
Prior art keywords
implants
calcium phosphate
composite layers
electrochemically deposited
phosphate composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002416201A
Other languages
French (fr)
Other versions
CA2416201C (en
Inventor
Hans-Georg Neumann
Peter Zeggel
Petra Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DOT GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2416201A1 publication Critical patent/CA2416201A1/en
Application granted granted Critical
Publication of CA2416201C publication Critical patent/CA2416201C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

The invention relates to calcium phosphate composite layers which are electrochemically deposited on bone implants. Implants which are coated in such a way are implanted without cement and are characterised by improved growing-in behaviour. Said highly porous composite layers on implants are made of at least two calcium phosphate phases of different solubility. The highly porous structure of said layers facilitates the immobilisation of cells from which new bone tissue can be made. The different solubility of the individual layer components ensures local concentration of calcium and phosphate ions which accelerates the incorporation process and which adapts to said process over the course of time.
CA002416201A 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants Expired - Fee Related CA2416201C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2000/006838 WO2002005862A1 (en) 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants

Publications (2)

Publication Number Publication Date
CA2416201A1 true CA2416201A1 (en) 2003-01-15
CA2416201C CA2416201C (en) 2008-11-18

Family

ID=8164028

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002416201A Expired - Fee Related CA2416201C (en) 2000-07-17 2000-07-17 Bioactive calcium phosphate composite layers electrochemically deposited on implants

Country Status (6)

Country Link
EP (1) EP1301220A1 (en)
JP (1) JP2004503333A (en)
AU (2) AU5985500A (en)
CA (1) CA2416201C (en)
HK (1) HK1060070A1 (en)
WO (1) WO2002005862A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007730A1 (en) * 2004-07-21 2006-01-26 The University Of British Columbia Method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant
US10004604B2 (en) 2006-09-08 2018-06-26 Kyocera Corporation Bioimplant for artifical joint with evanescent coating film
US10610614B2 (en) 2006-09-08 2020-04-07 Kyocera Corporation Bioimplant with evanescent coating film
US11278642B2 (en) 2006-09-08 2022-03-22 Takao Hotokebuchi Bioimplant with evanescent coating film
US12226550B2 (en) 2012-02-03 2025-02-18 Saga University Method of manufacturing a bioimplant

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012001260B4 (en) * 2012-01-23 2015-04-02 Dot Gmbh Antibacterial and osteoinductive implant coating

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
DE19504386C2 (en) * 1995-02-10 1997-08-28 Univ Dresden Tech Process for the production of a graded coating from calcium phosphate phases and metal oxide phases on metallic implants
EP0806212B1 (en) * 1996-05-10 2003-04-02 IsoTis N.V. Device for incorporation and release of biologically active agents
US6045683A (en) * 1997-12-01 2000-04-04 University Of Alabama In Huntsville Modified brushite surface coating, process therefor, and low temperature conversion to hydroxyapatite
AU766735B2 (en) * 1998-09-15 2003-10-23 Isotis N.V. Osteoinduction

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007730A1 (en) * 2004-07-21 2006-01-26 The University Of British Columbia Method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant
US10004604B2 (en) 2006-09-08 2018-06-26 Kyocera Corporation Bioimplant for artifical joint with evanescent coating film
US10610614B2 (en) 2006-09-08 2020-04-07 Kyocera Corporation Bioimplant with evanescent coating film
US11278642B2 (en) 2006-09-08 2022-03-22 Takao Hotokebuchi Bioimplant with evanescent coating film
US11998659B2 (en) 2006-09-08 2024-06-04 Kyocera Corporation Bioimplant with evanescent coating film
US12226550B2 (en) 2012-02-03 2025-02-18 Saga University Method of manufacturing a bioimplant

Also Published As

Publication number Publication date
AU2000259855A1 (en) 2002-05-02
EP1301220A1 (en) 2003-04-16
WO2002005862A8 (en) 2002-05-30
AU5985500A (en) 2002-01-30
AU2000259855B2 (en) 2006-02-02
CA2416201C (en) 2008-11-18
WO2002005862A1 (en) 2002-01-24
JP2004503333A (en) 2004-02-05
HK1060070A1 (en) 2004-07-30

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