[go: up one dir, main page]

CA2415068C - Renforcement global de l'organisme - Google Patents

Renforcement global de l'organisme Download PDF

Info

Publication number
CA2415068C
CA2415068C CA002415068A CA2415068A CA2415068C CA 2415068 C CA2415068 C CA 2415068C CA 002415068 A CA002415068 A CA 002415068A CA 2415068 A CA2415068 A CA 2415068A CA 2415068 C CA2415068 C CA 2415068C
Authority
CA
Canada
Prior art keywords
compositions
agents
composition
risk
chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002415068A
Other languages
English (en)
Other versions
CA2415068A1 (fr
Inventor
Matthew Joseph Doyle
Stephen Joseph Hunter-Rinderle
Robert Ernest Singer Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24431416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2415068(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of CA2415068A1 publication Critical patent/CA2415068A1/fr
Application granted granted Critical
Publication of CA2415068C publication Critical patent/CA2415068C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention vise à renforcer globalement l'organisme chez l'être humain et l'animal au moyen de compositions orales topiques contenant une quantité efficace et inoffensive d'un agent antimicrobien mélangé à un excipient pharmaceutiquement acceptable. Ces compositions permettent de lutter efficacement contre des maladies et des états pathologiques dus aux bactéries de la cavité buccale, et d'inhiber la dispersion dans la circulation sanguine de bactéries buccales pathogènes, de toxines et d'endotoxines bactériennes associées et des cytokines et médiateurs inflammatoires qui en résultent. L'invention concerne aussi des procédés d'utilisation de ces compositions, qui comprennent l'application topique dans la cavité buccale d'une quantité efficace et inoffensive d'un agent antimicrobien pour renforcer et/ou activer globalement l'organisme chez l'être humain et l'animal.
CA002415068A 2000-06-30 2001-06-28 Renforcement global de l'organisme Expired - Lifetime CA2415068C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60724000A 2000-06-30 2000-06-30
US09/607,240 2000-06-30
PCT/US2001/020516 WO2002002128A2 (fr) 2000-06-30 2001-06-28 Renforcement global de l'organisme

Publications (2)

Publication Number Publication Date
CA2415068A1 CA2415068A1 (fr) 2002-01-10
CA2415068C true CA2415068C (fr) 2009-03-10

Family

ID=24431416

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002415068A Expired - Lifetime CA2415068C (fr) 2000-06-30 2001-06-28 Renforcement global de l'organisme

Country Status (14)

Country Link
US (3) US20050163727A1 (fr)
EP (1) EP1294383B1 (fr)
JP (2) JP2004517038A (fr)
CN (1) CN1287803C (fr)
AT (1) ATE401089T1 (fr)
AU (1) AU2001271545A1 (fr)
CA (1) CA2415068C (fr)
DE (1) DE60134855D1 (fr)
DK (1) DK1294383T3 (fr)
ES (1) ES2309077T3 (fr)
MX (1) MXPA03000041A (fr)
PE (1) PE20020237A1 (fr)
PT (1) PT1294383E (fr)
WO (1) WO2002002128A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020049365A3 (fr) * 2018-08-10 2020-06-25 Chx Technologies, Inc., A Corporation Created And Existing Under The Laws Of Canada Procédé de prévention simultanée des caries et des maladies parodontales dans une seule procédure

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030206874A1 (en) * 1996-11-21 2003-11-06 The Proctor & Gamble Company Promoting whole body health
MXPA03000041A (es) * 2000-06-30 2003-10-15 Procter & Gamble Composiciones orales que comprenden agentes microbianos.
US8283135B2 (en) * 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
US6652841B1 (en) * 2002-08-28 2003-11-25 Colgate Palmolive Company Antiplaque enzyme containing dual component composition
US20040101494A1 (en) 2002-11-26 2004-05-27 Scott Douglas Craig Chewable solid unit dosage forms and methods for delivery of active agents into occlusal surfaces of teeth
US6669929B1 (en) 2002-12-30 2003-12-30 Colgate Palmolive Company Dentifrice containing functional film flakes
PL2105122T3 (pl) 2003-12-16 2013-03-29 Colgate Palmolive Co Kompozycja do higieny jamy ustnej i higieny osobistej i sposoby
US8628690B2 (en) * 2004-02-23 2014-01-14 The Texas A&M University System Nanoemulsion compositions and methods of use thereof
US7780873B2 (en) * 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
EP1750740A4 (fr) * 2004-05-06 2009-06-10 Molichem Medicines Inc Traitement de maladies et troubles associes aux membranes au moyen de compositions contenant des lantibiotiques
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
EP1671623A1 (fr) * 2004-10-01 2006-06-21 Giuseppe Vrespa Composition pour le traitement antibacteriel et anti-inflammatoire de la cavité buccale
DE102004052308B4 (de) * 2004-10-12 2013-04-04 Divapharma-Knufinke Arzneimittelwerk Gmbh Octenidinhaltige Lutschtabletten gegen entzündliche Erkrankungen des Mund- und Rachenraums
US8974772B2 (en) 2004-12-28 2015-03-10 Colgate-Palmolive Company Two phase toothpaste composition
DE102005002644A1 (de) * 2005-01-19 2006-07-20 Schülke & Mayr GmbH Zusammensetzungen für die hygienische Händedesinfektion und die desinfizierende Händewaschung
JP5024505B2 (ja) * 2005-03-25 2012-09-12 ライオン株式会社 歯周病に起因する高脂血症改善剤、ならびに口腔用組成物及び内服薬
US20060243298A1 (en) * 2005-04-28 2006-11-02 The Procter & Gamble Company Dental floss compositions comprising menthol and carboxamides
DE102005058978A1 (de) * 2005-08-26 2007-03-29 Bode Chemie Gmbh & Co. Kg Wund- und Schleimhautdesinfektionsmittel
DE102005045145A1 (de) * 2005-09-15 2007-03-29 Schülke & Mayr GmbH Verwendung von Octenidindihydrochlorid in halbfesten Zubereitungen
CN100356902C (zh) * 2005-09-21 2007-12-26 美晨集团股份有限公司 一种含有阴阳离子表面活性剂的牙膏及其制造方法
WO2007052436A1 (fr) * 2005-10-31 2007-05-10 Niigata University Microcapsule et son procede de fabrication
MX346202B (es) 2005-11-23 2017-03-09 Colgate Palmolive Co Metodos y composiciones de sal estañosa y tripolifosfato de sodio para el cuidado oral.
US20070254260A1 (en) * 2005-12-02 2007-11-01 Alden Wayne S Iv Oral care compositions, methods, devices and systems
GB0600431D0 (en) * 2006-01-10 2006-02-15 Sinclair Pharmaceuticals Ltd Method
GB0604018D0 (en) 2006-02-28 2006-04-05 Sinclair Pharmaceuticals Ltd Method
WO2007099060A2 (fr) * 2006-03-02 2007-09-07 Unilever N.V. Préparation
US20090208576A1 (en) * 2006-03-31 2009-08-20 Gandhi Anilkumar S Orally Disintegrating Tablets
BRPI0710643A2 (pt) * 2006-04-07 2011-08-23 Procter & Gamble regimes e kits para tratamento bucal
CA2848653A1 (fr) 2006-06-02 2007-12-13 Synedgen, Inc. Composes derives de chitosane-lysine
EP2049137A4 (fr) 2006-08-08 2013-05-01 Univ California Les salicylanilides renforcent l'administration par voie orale de peptides thérapeutiques
DE102006051891A1 (de) 2006-10-31 2008-05-08 Schülke & Mayr GmbH Antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
ES2442253T3 (es) * 2007-02-23 2014-02-10 The Procter & Gamble Company Composiciones orales de polifosfato
DE102007028184A1 (de) 2007-06-20 2008-12-24 Braun Gmbh Bürstenkopf für eine Zahnbürste
US20090151649A1 (en) * 2007-12-14 2009-06-18 Summit Applied Technologies, Inc. Chewable animal toy
US20090188521A1 (en) * 2008-01-17 2009-07-30 Evazynajad Ali M Dental Floss Formed from Botanic and Botanically Derived Fiber
DE102008011691A1 (de) * 2008-02-28 2009-09-10 Schülke & Mayr GmbH Stabilisierte, antimikrobiell wirksame Zusammensetzung mit einem Gehalt an Bispyridiniumalkan
US8343912B2 (en) 2008-12-23 2013-01-01 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
KR100935211B1 (ko) 2008-12-30 2010-01-06 남지원 소맥분 및 죽염을 함유하는 분말치약 조성물 및 그 제조방법
US10518113B2 (en) * 2009-04-02 2019-12-31 Colgate-Palmolive Company Dentifrice composition and method of use
CA2806539C (fr) * 2009-09-02 2018-08-07 Synedgen, Inc. Procedes et compositions de soins oraux utilisant des composes derives de chitosane
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
GB2481630A (en) * 2010-07-01 2012-01-04 Robert Taylor Composition for dental health
NZ606354A (en) 2010-08-07 2015-02-27 Univ New York State Res Found Oral compositions comprising a zinc compound and an anti-microbial agent
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
RU2013131014A (ru) 2010-12-07 2015-01-20 Колгейт-Палмолив Компани Композиции по уходу за полостью рта, содержащие хинон и дополнительный антимикробный агент
US10426761B2 (en) * 2011-04-19 2019-10-01 Arms Pharmaceutical, Llc Method for treatment of disease caused or aggravated by microorganisms or relieving symptoms thereof
US8731747B2 (en) 2011-04-28 2014-05-20 General Electric Company Communication systems and method for a rail vehicle or other powered system
US8510026B2 (en) 2011-06-13 2013-08-13 General Electric Company Data conversion system and method for converting data that is distributed in a vehicle
US8798807B2 (en) 2011-06-13 2014-08-05 General Electric Company Data distribution system and method for distributing data in a vehicle
US8620552B2 (en) 2011-06-13 2013-12-31 General Electric Company Data communication system and method for communicating data in a vehicle
JP5735898B2 (ja) * 2011-10-18 2015-06-17 東亜薬品株式会社 含嗽剤用液体組成物
WO2014098865A1 (fr) 2012-12-20 2014-06-26 Hill's Pet Nutrition, Inc. Expression de récepteurs de reconnaissance des motifs moléculaires pour la mesure de l'état de santé général
AU2014248562B2 (en) 2013-03-12 2019-01-03 Synedgen, Inc. Oral formulation of polyglucosamine derivatives in combination with a non-fermentable sugar
CN104628097B (zh) * 2013-11-11 2016-08-10 中国石油化工股份有限公司 一种杀菌缓蚀剂用组合物及其应用
EP3380066B1 (fr) 2015-12-30 2021-06-23 Colgate-Palmolive Company Compositions de soins buccaux
EP3380070A1 (fr) 2015-12-30 2018-10-03 Colgate-Palmolive Company Compositions d'hygiène bucco-dentaire
BR112018012947B1 (pt) 2015-12-30 2021-08-31 Colgate-Palmolive Company Composições para higiene pessoal
CA3009800C (fr) 2015-12-30 2024-01-16 Colgate-Palmolive Company Composition de soins personnels comprenant du fluorure d'etain et du pyrophosphate
CN106176546A (zh) * 2016-08-26 2016-12-07 湖北立天生物工程有限公司 基于壳聚糖衍生物深度清理、抑菌护齿漱口水及其制备方法
EP3668920A1 (fr) * 2017-08-15 2020-06-24 Sanford, L.P. Activateur de boue collante et procédés et kits associés
US10738175B2 (en) * 2017-08-15 2020-08-11 Sanford, L.P. Glue slime activator and associated methods and kits
US12053485B2 (en) 2018-06-25 2024-08-06 Triumph Pharmaceuticals Inc. Methods of inhibiting microbial infections using zinc-containing compositions
US11033485B1 (en) * 2019-05-16 2021-06-15 Shear Kershman Laboratories, Inc. Dental care system containing anti-tartar and anti-plaque actives
EP4210662A1 (fr) * 2020-09-08 2023-07-19 Unilever IP Holdings B.V. Compositions de soins buccodentaires

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2946725A (en) * 1957-03-25 1960-07-26 Procter & Gamble Dentifrice compositions
US4051234A (en) * 1975-06-06 1977-09-27 The Procter & Gamble Company Oral compositions for plaque, caries, and calculus retardation with reduced staining tendencies
US4206215A (en) * 1976-02-25 1980-06-03 Sterling Drug Inc. Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes
US4599228A (en) * 1981-01-19 1986-07-08 Vipont Laboratories, Inc. Antimicrobial agent
JPH0627058B2 (ja) * 1986-12-04 1994-04-13 ライオン株式会社 歯磨組成物
US4894220A (en) * 1987-01-30 1990-01-16 Colgate-Palmolive Company Antibacterial antiplaque oral composition
US5004597A (en) * 1987-09-14 1991-04-02 The Procter & Gamble Company Oral compositions comprising stannous flouride and stannous gluconate
US4902498A (en) * 1988-06-01 1990-02-20 The Procter & Gamble Company Oral compositions
US5334375A (en) * 1988-12-29 1994-08-02 Colgate Palmolive Company Antibacterial antiplaque oral composition
JPH0768109B2 (ja) * 1989-01-10 1995-07-26 株式会社オブジェ科学研究所 歯磨組成物
DE3925540C1 (fr) 1989-08-02 1990-08-30 Schuelke & Mayr Gmbh, 2000 Norderstedt, De
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5464609A (en) * 1990-03-16 1995-11-07 The Procter & Gamble Company Use of ketorolac for treatment of oral diseases and conditions
US5015466A (en) * 1990-06-26 1991-05-14 The Procter & Gamble Company Anticalculus compositions using tartrate-succinates
US5154917A (en) * 1990-09-11 1992-10-13 Beecham Inc. Color change mouthrinse
JP3157563B2 (ja) * 1991-10-29 2001-04-16 株式会社サンギ 歯磨剤
US5356615A (en) * 1991-01-30 1994-10-18 Colgate Palmolive Company Antiplaque oral compositions
GB9110721D0 (en) * 1991-05-17 1991-07-10 Unilever Plc Dentifrice compositions
GB9117315D0 (en) * 1991-08-09 1991-09-25 Unilever Plc Method of controlling dental tartar and compositions for use therein
JPH05163125A (ja) * 1991-12-13 1993-06-29 Shinagawa Fuel Co Ltd 口腔用組成物
US5294433A (en) * 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
US6004587A (en) * 1992-06-25 1999-12-21 Bioxy Inc. Therapeutic, production and immunostimulatory uses of biocidal compositions
US5830511A (en) * 1992-06-25 1998-11-03 Bioxy Inc. Therapeutic, production and immunostimulatory uses of biocidal compositions
JPH08505843A (ja) * 1992-12-18 1996-06-25 ザ、プロクター、エンド、ギャンブル、カンパニー 抗歯垢、抗歯石剤を含有した口内組成物
US5578293A (en) * 1994-12-06 1996-11-26 Colgate Palmolive Company Oral compositions containing stabilized stannous compounds having antiplaque and antitartar efficacy
US5639746A (en) * 1994-12-29 1997-06-17 The Procter & Gamble Company Hydroxamic acid-containing inhibitors of matrix metalloproteases
US5626838A (en) * 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5672598A (en) * 1995-03-21 1997-09-30 The Procter & Gamble Company Lactam-containing hydroxamic acids
CA2257990A1 (fr) * 1996-06-12 1997-12-18 The Procter & Gamble Company Utilisation d'antagonistes de h2 pour preparer une composition topique pour le traitement des rhumes
GB2317339A (en) * 1996-08-01 1998-03-25 Procter & Gamble Dentifrice composition containing a curcuminoid
US5753217A (en) * 1996-08-14 1998-05-19 William C. Christopfel Method of reducing oral malodor
KR20000035925A (ko) * 1996-08-28 2000-06-26 데이비드 엠 모이어 매트릭스 메탈로프로테아제 저해제인 포스핀산 아미드
IL128667A (en) * 1996-08-28 2002-04-21 Procter & Gamble Spirocyclic metroprotease inhibitors and pharmaceutical preparations containing them
US6187295B1 (en) * 1996-11-21 2001-02-13 The Procter & Gamble Company Methods of reducing the astringency of stannous in dentifrice compositions
US5939052A (en) * 1996-11-21 1999-08-17 The Procter & Gamble Company Dentifrice compositions containing polyphosphate and fluoride
AU7191898A (en) * 1997-06-25 1999-01-07 Mcneil-Ppc, Inc. Tartar control dental floss
US5875799A (en) * 1997-09-23 1999-03-02 Advanced Medical Instruments, Inc. Therapeutic dental floss for treating systemic diseases
US5875798A (en) * 1997-09-23 1999-03-02 Advanced Medical Instruments, Inc. Therapeutic toothpick for treating oral and systemic diseases
US6846478B1 (en) * 1998-02-27 2005-01-25 The Procter & Gamble Company Promoting whole body health
TR200100846T2 (tr) * 1998-09-23 2002-03-21 Unilever N.V. AĞìz bakìmìna iliçkin bileçimler
AU761437B2 (en) * 1998-11-30 2003-06-05 Procter & Gamble Company, The Method of reducing staining of stannous in dentifrice compositions
MXPA03000041A (es) * 2000-06-30 2003-10-15 Procter & Gamble Composiciones orales que comprenden agentes microbianos.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020049365A3 (fr) * 2018-08-10 2020-06-25 Chx Technologies, Inc., A Corporation Created And Existing Under The Laws Of Canada Procédé de prévention simultanée des caries et des maladies parodontales dans une seule procédure

Also Published As

Publication number Publication date
JP2008143910A (ja) 2008-06-26
EP1294383B1 (fr) 2008-07-16
AU2001271545A1 (en) 2002-01-14
MXPA03000041A (es) 2003-10-15
ATE401089T1 (de) 2008-08-15
US20050163727A1 (en) 2005-07-28
ES2309077T3 (es) 2008-12-16
CA2415068A1 (fr) 2002-01-10
JP2004517038A (ja) 2004-06-10
WO2002002128A2 (fr) 2002-01-10
DK1294383T3 (da) 2008-11-10
CN1287803C (zh) 2006-12-06
EP1294383A2 (fr) 2003-03-26
DE60134855D1 (de) 2008-08-28
WO2002002128A3 (fr) 2002-04-25
CN1522149A (zh) 2004-08-18
PT1294383E (pt) 2008-10-08
US20110306018A1 (en) 2011-12-15
PE20020237A1 (es) 2002-04-18
US20070140987A1 (en) 2007-06-21

Similar Documents

Publication Publication Date Title
CA2415068C (fr) Renforcement global de l'organisme
US6846478B1 (en) Promoting whole body health
US6350438B1 (en) Oral care compositions comprising chlorite and methods
US20030206874A1 (en) Promoting whole body health
JP5280366B2 (ja) 抗菌剤及び宿主反応調節剤の組み合わせを含有する口腔ケア組成物
US6696047B2 (en) Stable oral care compositions comprising chlorite
US8277782B2 (en) Topical oral care compositions comprising host response modulating agents
US20120263657A1 (en) Promoting Whole Body Health

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20210628