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CA2392474A1 - Reseaux de sondes d'acides nucleiques - Google Patents

Reseaux de sondes d'acides nucleiques Download PDF

Info

Publication number
CA2392474A1
CA2392474A1 CA002392474A CA2392474A CA2392474A1 CA 2392474 A1 CA2392474 A1 CA 2392474A1 CA 002392474 A CA002392474 A CA 002392474A CA 2392474 A CA2392474 A CA 2392474A CA 2392474 A1 CA2392474 A1 CA 2392474A1
Authority
CA
Canada
Prior art keywords
nucleic acid
region
target nucleic
anchor
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392474A
Other languages
English (en)
Inventor
Jonathan M. Rothberg
Joel S. Bader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
454 Life Science Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392474A1 publication Critical patent/CA2392474A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Nanotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Composite Materials (AREA)
  • Biophysics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

L'invention concerne des réseaux de sondes d'acides nucléiques et des méthodes d'identification et de séquencage des acides nucléiques dans une population d'acides nucléiques à l'aide de ces réseaux.
CA002392474A 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques Abandoned CA2392474A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44940299A 1999-11-26 1999-11-26
US09/449,402 1999-11-26
PCT/US2000/032131 WO2001038580A2 (fr) 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques

Publications (1)

Publication Number Publication Date
CA2392474A1 true CA2392474A1 (fr) 2001-05-31

Family

ID=23784034

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392474A Abandoned CA2392474A1 (fr) 1999-11-26 2000-11-27 Reseaux de sondes d'acides nucleiques

Country Status (5)

Country Link
EP (1) EP1234058A2 (fr)
JP (1) JP2003515149A (fr)
AU (1) AU783841B2 (fr)
CA (1) CA2392474A1 (fr)
WO (1) WO2001038580A2 (fr)

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* Cited by examiner, † Cited by third party
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GB2378245A (en) * 2001-08-03 2003-02-05 Mats Nilsson Nucleic acid amplification method
US9388459B2 (en) * 2002-06-17 2016-07-12 Affymetrix, Inc. Methods for genotyping
US9487823B2 (en) 2002-12-20 2016-11-08 Qiagen Gmbh Nucleic acid amplification
US6977153B2 (en) * 2002-12-31 2005-12-20 Qiagen Gmbh Rolling circle amplification of RNA
EP1598427A1 (fr) * 2004-05-17 2005-11-23 Charité - Universitätsmedizin Berlin Méthode pour l'amplification d'acide nucléique cible
AU2005250432B2 (en) 2004-05-28 2011-09-15 Asuragen, Inc. Methods and compositions involving microRNA
ES2503739T3 (es) 2004-11-12 2014-10-07 Asuragen, Inc. Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN
EP3492602A1 (fr) 2005-06-15 2019-06-05 Complete Genomics, Inc. Réseaux de molécules simples pour l'analyse génétique et chimique
EP1762627A1 (fr) 2005-09-09 2007-03-14 Qiagen GmbH Procédé pour l'activation d'acides nucléiques pour effectuer une réaction d'une polymérase
US11306351B2 (en) 2005-12-21 2022-04-19 Affymetrix, Inc. Methods for genotyping
JP2010510964A (ja) 2006-09-19 2010-04-08 アシュラジェン インコーポレイテッド 治療的介入の標的としての、ｍｉＲ−１５、ｍｉＲ−２６、ｍｉＲ−３１、ｍｉＲ−１４５、ｍｉＲ−１４７、ｍｉＲ−１８８、ｍｉＲ−２１５、ｍｉＲ−２１６、ｍｉＲ−３３１、ｍｍｕ−ｍｉＲ−２９２−３ｐによって調節される遺伝子および経路
WO2008036765A2 (fr) 2006-09-19 2008-03-27 Asuragen, Inc. Micro arn exprimés par différenciation dans les maladies du pancréas, et leur utilisation
EP2617837A3 (fr) 2007-06-08 2013-10-23 Biogen Idec MA Inc. Biomarqueurs pour prédire une réactivité ou non réactivité anti-TNF
JP5020734B2 (ja) * 2007-07-31 2012-09-05 株式会社日立ハイテクノロジーズ 核酸解析方法及び装置
EP2990487A1 (fr) 2008-05-08 2016-03-02 Asuragen, INC. Compositions et procédés relatifs à la modulation de miarn de néovascularisation ou angiogenèse
US8486630B2 (en) * 2008-11-07 2013-07-16 Industrial Technology Research Institute Methods for accurate sequence data and modified base position determination
GB0921264D0 (en) 2009-12-03 2010-01-20 Olink Genomics Ab Method for amplification of target nucleic acid
WO2011100503A1 (fr) 2010-02-11 2011-08-18 Dana Farber Cancer Institute, Inc. Procédés pour prédire la probabilité de réponse à un traitement
WO2011108930A1 (fr) 2010-03-04 2011-09-09 Interna Technologies Bv Molécule de miarn définie par sa source et ses utilisations thérapeutiques et en diagnostic pour maladies ou états associés à l'emt
EP3369817A1 (fr) 2010-07-06 2018-09-05 InteRNA Technologies B.V. Arnmi, son diagnostic et ses usages thérapeutiques dans des maladies ou des pathologies associées à un mélanome ou dans des maladies ou pathologies associées à une voie braf activée
EP2772550B1 (fr) 2010-11-17 2017-03-29 Interpace Diagnostics, LLC Micro-ARN comme biomarqueurs pour différencier des néoplasmes de thyroïde bénins et malins
EP2474617A1 (fr) 2011-01-11 2012-07-11 InteRNA Technologies BV MIR pour traiter une nouvelle angiogenèse
WO2012158238A2 (fr) 2011-02-28 2012-11-22 University Of Iowa Research Foundation Changements d'hormone antimullérienne dans la grossesse et prédiction d'évolution indésirable de grossesse et du sexe
CN102732598B (zh) * 2011-04-11 2017-03-01 陈先锋 一种全基因组dna序列拼接测序方法
WO2012168803A2 (fr) * 2011-06-07 2012-12-13 Koninklijke Philips Electronics N.V. Fourniture de données de séquence nucléotidique
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
WO2013063519A1 (fr) 2011-10-26 2013-05-02 Asuragen, Inc. Procédés et compositions faisant intervenir des taux d'expression de miarn pour distinguer des kystes pancréatiques
US20130142728A1 (en) 2011-10-27 2013-06-06 Asuragen, Inc. Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors
US20150152499A1 (en) 2012-07-03 2015-06-04 Interna Technologies B.V. Diagnostic portfolio and its uses
US20140100124A1 (en) 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
KR101984700B1 (ko) * 2012-11-19 2019-05-31 삼성전자주식회사 폴리뉴클레오티드 및 그의 용도
CA2905949A1 (fr) 2013-03-15 2014-09-25 Baylor Research Institute Marqueurs d'une neoplasie colorectale associee a la colite ulcereuse (uc)
ES2935257T3 (es) 2013-03-15 2023-03-03 Univ Chicago Métodos y composiciones relacionadas con la actividad de las células T
CA2907377A1 (fr) 2013-03-15 2014-09-18 Baylor Research Institute Biomarqueurs de miarn a base de tissu et de sang pour le diagnostic, le pronostic et le potentiel predictif de metastases dans le cancer colorectal
WO2017062863A1 (fr) 2015-10-09 2017-04-13 Accuragen Holdings Limited Procédés et compositions pour enrichissement de produits d'amplification
US11286519B2 (en) 2013-12-11 2022-03-29 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
US11859246B2 (en) * 2013-12-11 2024-01-02 Accuragen Holdings Limited Methods and compositions for enrichment of amplification products
KR102379877B1 (ko) 2013-12-11 2022-03-30 아큐라젠 홀딩스 리미티드 희귀 서열 변이를 검출하기 위한 조성물 및 방법
CA2980811A1 (fr) 2015-04-02 2016-10-06 Hmnc Value Gmbh Methode de traitement utilisant les predicteurs genetiques d'une reponse a un traitement base sur des antagonistes du crhr1
CN108699505A (zh) 2015-12-03 2018-10-23 安可济控股有限公司 用于形成连接产物的方法和组合物
WO2017135383A1 (fr) * 2016-02-03 2017-08-10 国立大学法人豊橋技術科学大学 Pseudo polynucléotide cyclique double brin, et inhibiteur d'expression de gène
EP3458586B1 (fr) 2016-05-16 2022-12-28 Accuragen Holdings Limited Procédé de séquençage amélioré par identification de brin
WO2018035170A1 (fr) 2016-08-15 2018-02-22 Accuragen Holdings Limited Compositions et procédés permettant de détecter des variants de séquences rares
US20190309352A1 (en) * 2016-11-16 2019-10-10 Progenity, Inc Multimodal assay for detecting nucleic acid aberrations
US11497762B2 (en) 2017-11-03 2022-11-15 Interna Technologies B.V. MiRNA molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation
US11203782B2 (en) 2018-03-29 2021-12-21 Accuragen Holdings Limited Compositions and methods comprising asymmetric barcoding
WO2019241290A1 (fr) 2018-06-12 2019-12-19 Accuragen Holdings Limited Méthodes et compositions pour former des produits de ligature
JP7566775B2 (ja) 2019-04-12 2024-10-15 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 筋肉量及び酸化的代謝を増加させるための組成物及び方法
WO2024028794A1 (fr) 2022-08-02 2024-02-08 Temple Therapeutics BV Méthodes de traitement de troubles de l'endomètre et de l'hyperprolifération ovarienne

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5503980A (en) * 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
US5854033A (en) * 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
SE9701783D0 (sv) * 1997-05-14 1997-05-14 Marek Kwiatkowski In situ synthesis of oligonucleotides of inverse orientation
JP2002501760A (ja) * 1998-02-02 2002-01-22 アマーシャム・ファルマシア・バイオテック・アクチボラグ 核酸解析方法
CA2325468C (fr) * 1998-03-25 2008-11-18 Ulf Landegren Replication en cercle roulant destinee a des sondes cadenas
AU3567099A (en) * 1998-04-16 1999-11-01 Packard Bioscience Company Analysis of polynucleotide sequence

Also Published As

Publication number Publication date
AU783841B2 (en) 2005-12-15
WO2001038580A3 (fr) 2002-04-25
EP1234058A2 (fr) 2002-08-28
AU1792701A (en) 2001-06-04
WO2001038580A9 (fr) 2002-12-05
JP2003515149A (ja) 2003-04-22
WO2001038580A2 (fr) 2001-05-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued