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CA2388777A1 - 18 proteines secretees humaines - Google Patents

18 proteines secretees humaines Download PDF

Info

Publication number
CA2388777A1
CA2388777A1 CA002388777A CA2388777A CA2388777A1 CA 2388777 A1 CA2388777 A1 CA 2388777A1 CA 002388777 A CA002388777 A CA 002388777A CA 2388777 A CA2388777 A CA 2388777A CA 2388777 A1 CA2388777 A1 CA 2388777A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
human
polypeptides
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002388777A
Other languages
English (en)
Inventor
Steven M. Ruben
George A. Komatsoulis
Kevin P. Baker
Paul E. Young
Gil H. Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2388777A1 publication Critical patent/CA2388777A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne de nouvelles protéines sécrétées humaines et des acides nucléiques isolés contenant les régions codantes des gènes codant pour ces protéines. L'invention concerne également des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison permettant de produire les protéines sécrétées humaines. L'invention concerne en outre des méthodes diagnostiques et thérapeutiques utiles pour diagnostiquer et traiter des maladies, des troubles et/ou des conditions liés à ces nouvelles protéines sécrétées humaines.
CA002388777A 1999-11-19 2000-11-15 18 proteines secretees humaines Abandoned CA2388777A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16641599P 1999-11-19 1999-11-19
US60/166,415 1999-11-19
US21513600P 2000-06-30 2000-06-30
US60/215,136 2000-06-30
PCT/US2000/031162 WO2001036432A2 (fr) 1999-11-19 2000-11-15 18 proteines secretees humaines

Publications (1)

Publication Number Publication Date
CA2388777A1 true CA2388777A1 (fr) 2001-05-25

Family

ID=26862246

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002388777A Abandoned CA2388777A1 (fr) 1999-11-19 2000-11-15 18 proteines secretees humaines

Country Status (5)

Country Link
EP (1) EP1234030A4 (fr)
JP (1) JP2003514541A (fr)
AU (1) AU1604401A (fr)
CA (1) CA2388777A1 (fr)
WO (1) WO2001036432A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
US7419663B2 (en) 1998-03-20 2008-09-02 Genentech, Inc. Treatment of complement-associated disorders
US7192589B2 (en) 1998-09-16 2007-03-20 Genentech, Inc. Treatment of inflammatory disorders with STIgMA immunoadhesins
ES2330330T3 (es) 2000-06-28 2009-12-09 Glycofi, Inc. Procedimiento de produccion de glucoproteinas modificadas.
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7598055B2 (en) 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
CA2420140A1 (fr) * 2000-08-24 2002-02-28 Genentech, Inc. Compositions et procedes de diagnostic et traitement de tumeurs
US20040152105A1 (en) * 2002-09-06 2004-08-05 Cytos Biotechnology Ag. Immune modulatory compounds and methods
US7332299B2 (en) 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
JP4897690B2 (ja) * 2004-10-12 2012-03-14 ジェネンテック， インコーポレイテッド 補体関連障害の予防および処置のためのＣＲＩｇポリペプチド
CA2903896A1 (fr) 2005-11-04 2007-05-18 Genentech, Inc. Utilisation d'inhibiteurs de la voie du complement pour traiter des maladies oculaires
US7776573B2 (en) 2006-06-01 2010-08-17 Genentech, Inc. Crystal structure of CRIg and C3b:CRIg complex
TW201716437A (zh) 2006-11-02 2017-05-16 建南德克公司 人類化之抗-因子ｄ抗體及其用途
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
AU2009244300B2 (en) 2008-05-06 2014-04-17 Genentech, Inc. Affinity matured CRIg variants
KR101137019B1 (ko) * 2009-05-25 2012-05-24 한국생명공학연구원 신규한 ｇｐｃｒ 단백질 및 이의 용도
WO2011127418A1 (fr) 2010-04-09 2011-10-13 Amgen Inc. Protéines btnl9, acides nucléiques, et anticorps et leurs utilisations
KR20160042438A (ko) 2013-08-12 2016-04-19 제넨테크, 인크. 보체-연관 상태의 치료를 위한 조성물 및 방법
JP2017515811A (ja) 2014-05-01 2017-06-15 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体変異体及びその使用法
CN108472382A (zh) 2015-10-30 2018-08-31 豪夫迈·罗氏有限公司 抗-因子d抗体变体缀合物及其用途
JP2018534930A (ja) 2015-10-30 2018-11-29 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体及びコンジュゲート
JP7076076B2 (ja) * 2016-03-03 2022-05-27 東亞合成株式会社 シグナルペプチドを指標にした筋萎縮性側索硬化症の診断方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999001550A1 (fr) * 1997-07-03 1999-01-14 Dana-Farber Cancer Institute Procede de detection de modifications de msh5
JPH11313673A (ja) * 1998-04-30 1999-11-16 Hoechst Marion Roussel Kk ヒトｂｍｐ−２プロモーターおよびこれを用いた骨関連物質の探索法
CA2384659A1 (fr) * 1999-09-27 2001-04-05 Craig A. Rosen 37 proteines secretees humaines

Also Published As

Publication number Publication date
WO2001036432A2 (fr) 2001-05-25
WO2001036432A3 (fr) 2002-05-10
EP1234030A2 (fr) 2002-08-28
JP2003514541A (ja) 2003-04-22
AU1604401A (en) 2001-05-30
EP1234030A4 (fr) 2003-05-07

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Legal Events

Date Code Title Description
FZDE Dead