CA2361612A1 - Activites de modulation des peptides de l'heparine, et d'autres glycosaminoglycanes ou proteoglycanes - Google Patents
Activites de modulation des peptides de l'heparine, et d'autres glycosaminoglycanes ou proteoglycanes Download PDFInfo
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- CA2361612A1 CA2361612A1 CA002361612A CA2361612A CA2361612A1 CA 2361612 A1 CA2361612 A1 CA 2361612A1 CA 002361612 A CA002361612 A CA 002361612A CA 2361612 A CA2361612 A CA 2361612A CA 2361612 A1 CA2361612 A1 CA 2361612A1
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- mammal
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- RCKMWOKWVGPNJF-UHFFFAOYSA-N diethylcarbamazine Chemical compound CCN(CC)C(=O)N1CCN(C)CC1 RCKMWOKWVGPNJF-UHFFFAOYSA-N 0.000 description 1
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- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical compound OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
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- 238000002823 phage display Methods 0.000 description 1
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- 239000006187 pill Substances 0.000 description 1
- 235000021018 plums Nutrition 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 229920000724 poly(L-arginine) polymer Polymers 0.000 description 1
- 229920000729 poly(L-lysine) polymer Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000005020 polyethylene terephthalate Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
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- 238000000926 separation method Methods 0.000 description 1
- 108010080511 serum sodium transport inhibitor Proteins 0.000 description 1
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- 239000010703 silicon Substances 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 101150052401 slc44a1 gene Proteins 0.000 description 1
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- 238000005670 sulfation reaction Methods 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
L'invention concerne des peptides de différentes séquences et tailles, et des techniques d'utilisation de ces peptides qui présentent une forte affinité pour les glycosaminoglycanes et les protéoglycanes, ces peptides réagissant fortement avec l'héparine, et d'autres glycosaminoglycanes, ou protéoglycanes (PG).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11827699P | 1999-02-02 | 1999-02-02 | |
| US60/118,276 | 1999-02-02 | ||
| PCT/US2000/002853 WO2000045831A1 (fr) | 1999-02-02 | 2000-02-02 | Activites de modulation des peptides de l'heparine, et d'autres glycosaminoglycanes ou proteoglycanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2361612A1 true CA2361612A1 (fr) | 2000-08-10 |
Family
ID=22377591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002361612A Abandoned CA2361612A1 (fr) | 1999-02-02 | 2000-02-02 | Activites de modulation des peptides de l'heparine, et d'autres glycosaminoglycanes ou proteoglycanes |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1156816A4 (fr) |
| CA (1) | CA2361612A1 (fr) |
| WO (1) | WO2000045831A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003595B2 (en) | 2000-03-01 | 2011-08-23 | Cellectis | Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei |
| US20040097586A1 (en) * | 2001-01-30 | 2004-05-20 | Andre Trouet | Anti-tumor compounds |
| US7049286B2 (en) | 2001-08-30 | 2006-05-23 | Diatos, S.A. | Insulin conjugates and methods of use thereof |
| WO2003054146A2 (fr) | 2001-11-14 | 2003-07-03 | Northwestern University | Auto-assemblage et mineralisation de nanofibres de peptide amphiphile |
| US7371719B2 (en) | 2002-02-15 | 2008-05-13 | Northwestern University | Self-assembly of peptide-amphiphile nanofibers under physiological conditions |
| WO2004018628A2 (fr) | 2002-08-21 | 2004-03-04 | Northwestern University | Solutions chargees de peptides amphiphiles, et reseaux auto-assembles de nanofibres de peptides en etant faits |
| US7554021B2 (en) | 2002-11-12 | 2009-06-30 | Northwestern University | Composition and method for self-assembly and mineralization of peptide amphiphiles |
| WO2004046167A2 (fr) | 2002-11-14 | 2004-06-03 | Northwestern University | Synthese et auto-ssemblage du peptide bola tribloc abc |
| IL153762A0 (en) * | 2002-12-31 | 2003-07-06 | Rimonyx Pharmaceuticals Ltd | Methods of screening for anti-inflammatory drugs and use thereof |
| WO2005014619A2 (fr) | 2003-03-28 | 2005-02-17 | Thomas Jefferson University | Peptides de liaison a l'heparine et leur utilisation |
| WO2005018650A2 (fr) | 2003-08-14 | 2005-03-03 | Diatos | Composition anti-bacterienne plus particulierement contre les bacteries gram negatif comprenent un peptide et un agent anti-bacterien avantageusement hydrophobe |
| NZ547671A (en) | 2003-12-05 | 2009-10-30 | Univ Northwestern | Self-assembling peptide amphiphiles and related methods for growth factor delivery |
| CN1905893A (zh) | 2003-12-05 | 2007-01-31 | 西北大学 | 分支的肽两亲物、相关的表位组合物和其自组装的结构 |
| EP1853917A4 (fr) * | 2005-03-04 | 2008-09-10 | Univ Northwestern | Epitopes angiogéniques de liaison a l'héparine, amphiphiles peptidiques, compositions auto-assemblées et procédés d'utilisation associés |
| EP1797901A1 (fr) | 2005-12-16 | 2007-06-20 | Diatos | Conjugués peptidiques pénétrant dans les cellules en tant que vecteurs pour l'administration d'acides nucléiques |
| EP1818395A1 (fr) | 2006-02-08 | 2007-08-15 | Diatos | Compositions et méthodes pour le traitement de maladies lysosomales |
| KR101394768B1 (ko) | 2006-03-30 | 2014-05-21 | 드라이스 파마슈티컬스 아이엔씨 | 캄토테신-세포 투과 펩티드 결합체 및 이를 포함하는 약학 조성물 |
| US8076295B2 (en) | 2007-04-17 | 2011-12-13 | Nanotope, Inc. | Peptide amphiphiles having improved solubility and methods of using same |
| US8450271B2 (en) | 2009-04-13 | 2013-05-28 | Northwestern University | Peptide-based scaffolds for cartilage regeneration and methods for their use |
| US10222410B2 (en) * | 2013-02-12 | 2019-03-05 | Headsight, Inc. | Diagnostic system for a controller |
| WO2024261742A1 (fr) | 2023-06-21 | 2024-12-26 | Nano Ghost Ltd | Compositions comprenant des médicaments insolubles dans l'eau et leurs procédés de production et d'utilisation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770563A (en) * | 1991-12-06 | 1998-06-23 | The United States Of America As Represented By The Department Of Health And Human Services | Heparin- and sulfatide binding peptides from the type I repeats of human thrombospondin and conjugates thereof |
| US5614494A (en) * | 1993-11-12 | 1997-03-25 | University Of Michigan, The Board Of Regents Acting For And On Behalf Of | Peptides for heparin and low molecular weight heparin anticoagulation reversal |
| US5877153A (en) * | 1996-06-11 | 1999-03-02 | Commonwealth Biotechnologies Inc. | Heparin-binding peptides |
-
2000
- 2000-02-02 CA CA002361612A patent/CA2361612A1/fr not_active Abandoned
- 2000-02-02 EP EP00905964A patent/EP1156816A4/fr not_active Withdrawn
- 2000-02-02 WO PCT/US2000/002853 patent/WO2000045831A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1156816A4 (fr) | 2004-12-29 |
| EP1156816A1 (fr) | 2001-11-28 |
| WO2000045831A1 (fr) | 2000-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |