CA2341646A1 - Method for producing solid dosing forms - Google Patents
Method for producing solid dosing forms Download PDFInfo
- Publication number
- CA2341646A1 CA2341646A1 CA002341646A CA2341646A CA2341646A1 CA 2341646 A1 CA2341646 A1 CA 2341646A1 CA 002341646 A CA002341646 A CA 002341646A CA 2341646 A CA2341646 A CA 2341646A CA 2341646 A1 CA2341646 A1 CA 2341646A1
- Authority
- CA
- Canada
- Prior art keywords
- agent
- solid dosing
- dosing forms
- plastic mixture
- producing solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000004033 plastic Substances 0.000 abstract 3
- 238000007493 shaping process Methods 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 239000007767 bonding agent Substances 0.000 abstract 1
- 239000003086 colorant Substances 0.000 abstract 1
- 150000002634 lipophilic molecules Chemical class 0.000 abstract 1
- 230000001050 lubricating effect Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Laminated Bodies (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a method for producing solid dosing forms by forming a plastic mixture comprised of at least one polymeric bonding agent, at least one active substance, and of optional common additives, and by shaping the plastic mixture into the solid dosing forms using a form tool. During shaping, an agent with modified surface properties is deposited on the surface of the plastic mixture in a finely dispersed manner. Said agent with modified surface properties is preferably a surfactant, a lipophilic compound, an antioxidant, a colorant or an agent with an antistatic action and/or lubricating action.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19839276.1 | 1998-08-28 | ||
DE19839276A DE19839276A1 (en) | 1998-08-28 | 1998-08-28 | Process for the preparation of solid dosage forms |
PCT/EP1999/006314 WO2000012068A1 (en) | 1998-08-28 | 1999-08-27 | Method for producing solid dosing forms |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2341646A1 true CA2341646A1 (en) | 2000-03-09 |
CA2341646C CA2341646C (en) | 2008-10-21 |
Family
ID=7879077
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002341646A Expired - Lifetime CA2341646C (en) | 1998-08-28 | 1999-08-27 | Method for producing solid dosing forms |
Country Status (9)
Country | Link |
---|---|
US (1) | US6669879B1 (en) |
EP (1) | EP1107739B1 (en) |
JP (1) | JP2002523185A (en) |
CN (1) | CN1170525C (en) |
AT (1) | ATE235896T1 (en) |
CA (1) | CA2341646C (en) |
DE (2) | DE19839276A1 (en) |
ES (1) | ES2196853T3 (en) |
WO (1) | WO2000012068A1 (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7364752B1 (en) | 1999-11-12 | 2008-04-29 | Abbott Laboratories | Solid dispersion pharamaceutical formulations |
EP1175205B1 (en) | 1999-11-12 | 2006-06-14 | Abbott Laboratories | Solid dispersion comprising ritonavir, fenofibrate or griseofulvin |
DE10026698A1 (en) | 2000-05-30 | 2001-12-06 | Basf Ag | Self-emulsifying active ingredient formulation and use of this formulation |
GB0113841D0 (en) * | 2001-06-07 | 2001-08-01 | Boots Co Plc | Therapeutic agents |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US7927616B2 (en) * | 2004-01-16 | 2011-04-19 | Thomas T. Yamashita | Pesticide compositions and methods for their use |
CA2568378C (en) * | 2004-05-28 | 2013-03-19 | Abbott Gmbh & Co. Kg | Formulation obtained from a powder mixture comprising an inorganic pigment |
WO2006045152A1 (en) * | 2004-10-29 | 2006-05-04 | Mayne Pharma International Pty Ltd | Improved tabletting process |
EP1674399B1 (en) * | 2004-12-22 | 2006-11-22 | Mattern, Udo | Use of a container made of a plastic material containing an inorganic additive |
US20060140820A1 (en) | 2004-12-28 | 2006-06-29 | Udo Mattern | Use of a container of an inorganic additive containing plastic material |
US8404275B2 (en) | 2007-07-01 | 2013-03-26 | Vitalis Llc | Combination tablet with chewable outer layer |
KR20110020782A (en) * | 2008-04-24 | 2011-03-03 | 이브스트라, 인코포레이티드 | Oral contraceptive formulations comprising progestogen and estrogen dispersed in enteric polymer |
DE102011010437A1 (en) * | 2011-02-04 | 2012-08-09 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Tableting aids |
US20130040923A1 (en) | 2011-05-13 | 2013-02-14 | Trimel Pharmaceuticals Corporation | Intranasal lower dosage strength testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
US20130045958A1 (en) | 2011-05-13 | 2013-02-21 | Trimel Pharmaceuticals Corporation | Intranasal 0.15% and 0.24% testosterone gel formulations and use thereof for treating anorgasmia or hypoactive sexual desire disorder |
US9757388B2 (en) | 2011-05-13 | 2017-09-12 | Acerus Pharmaceuticals Srl | Intranasal methods of treating women for anorgasmia with 0.6% and 0.72% testosterone gels |
CN104105478A (en) | 2011-10-28 | 2014-10-15 | 维塔利斯公司 | Anti-flush compositions |
CN102697660B (en) * | 2012-06-04 | 2014-02-12 | 贵州景峰注射剂有限公司 | Method for eliminating static electricity in micro-pill room |
US11744838B2 (en) | 2013-03-15 | 2023-09-05 | Acerus Biopharma Inc. | Methods of treating hypogonadism with transnasal testosterone bio-adhesive gel formulations in male with allergic rhinitis, and methods for preventing an allergic rhinitis event |
US9375033B2 (en) | 2014-02-14 | 2016-06-28 | R.J. Reynolds Tobacco Company | Tobacco-containing gel composition |
US20170182070A1 (en) | 2014-10-08 | 2017-06-29 | Mayne Pharma International Pty Ltd. | Controlled Release Doxycycline |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3612211A1 (en) | 1986-04-11 | 1987-10-15 | Basf Ag | CONTINUOUS TABLET METHOD |
WO1993007859A1 (en) | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
JPH06218028A (en) | 1992-10-02 | 1994-08-09 | Eisai Co Ltd | Method and apparatus for molding wet-processed tablet, and the wet-processed tablet |
DE4446468A1 (en) | 1994-12-23 | 1996-06-27 | Basf Ag | Process for the production of coated tablets |
DE4446467A1 (en) * | 1994-12-23 | 1996-06-27 | Basf Ag | Process for the production of lenticular tablets by melt calendering |
DE19710213A1 (en) * | 1997-03-12 | 1998-09-17 | Basf Ag | Process for the manufacture of solid combination dosage forms |
-
1998
- 1998-08-28 DE DE19839276A patent/DE19839276A1/en not_active Withdrawn
-
1999
- 1999-08-27 DE DE59904868T patent/DE59904868D1/en not_active Expired - Lifetime
- 1999-08-27 JP JP2000567188A patent/JP2002523185A/en active Pending
- 1999-08-27 WO PCT/EP1999/006314 patent/WO2000012068A1/en active IP Right Grant
- 1999-08-27 US US09/763,662 patent/US6669879B1/en not_active Expired - Lifetime
- 1999-08-27 AT AT99946047T patent/ATE235896T1/en not_active IP Right Cessation
- 1999-08-27 EP EP99946047A patent/EP1107739B1/en not_active Expired - Lifetime
- 1999-08-27 ES ES99946047T patent/ES2196853T3/en not_active Expired - Lifetime
- 1999-08-27 CA CA002341646A patent/CA2341646C/en not_active Expired - Lifetime
- 1999-08-27 CN CNB998127876A patent/CN1170525C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE59904868D1 (en) | 2003-05-08 |
JP2002523185A (en) | 2002-07-30 |
CN1170525C (en) | 2004-10-13 |
EP1107739A1 (en) | 2001-06-20 |
ATE235896T1 (en) | 2003-04-15 |
EP1107739B1 (en) | 2003-04-02 |
CA2341646C (en) | 2008-10-21 |
US6669879B1 (en) | 2003-12-30 |
WO2000012068A1 (en) | 2000-03-09 |
CN1325298A (en) | 2001-12-05 |
ES2196853T3 (en) | 2003-12-16 |
DE19839276A1 (en) | 2000-03-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20190827 |