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CA2339384A1 - Improved method for targeted topical treatment of disease - Google Patents

Improved method for targeted topical treatment of disease Download PDF

Info

Publication number
CA2339384A1
CA2339384A1 CA002339384A CA2339384A CA2339384A1 CA 2339384 A1 CA2339384 A1 CA 2339384A1 CA 002339384 A CA002339384 A CA 002339384A CA 2339384 A CA2339384 A CA 2339384A CA 2339384 A1 CA2339384 A1 CA 2339384A1
Authority
CA
Canada
Prior art keywords
disease
improved method
topical treatment
targeted topical
targeted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002339384A
Other languages
French (fr)
Other versions
CA2339384C (en
Inventor
H. Craig Dees
Timothy Scott
John Smolik
Eric A. Wachter
Walter Fisher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Provectus Pharmatech Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2339384A1 publication Critical patent/CA2339384A1/en
Application granted granted Critical
Publication of CA2339384C publication Critical patent/CA2339384C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22062—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation to be filled with liquid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22051—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation
    • A61B2017/22065—Functions of balloons
    • A61B2017/22069—Immobilising; Stabilising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22087—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance photodynamic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Radiation-Therapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Laser Surgery Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method and apparatus for topical treatment of diseased tissue, including topical or systemic application of a PDT agent to diseased tissue, followed by topical application of light (24).
CA002339384A 1998-08-06 1999-08-02 Improved method for targeted topical treatment of disease Expired - Lifetime CA2339384C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13004198A 1998-08-06 1998-08-06
US09/130,041 1998-08-06
PCT/US1999/017515 WO2000007515A1 (en) 1998-08-06 1999-08-02 Improved method for targeted topical treatment of disease

Publications (2)

Publication Number Publication Date
CA2339384A1 true CA2339384A1 (en) 2000-02-17
CA2339384C CA2339384C (en) 2008-07-08

Family

ID=22442778

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002339384A Expired - Lifetime CA2339384C (en) 1998-08-06 1999-08-02 Improved method for targeted topical treatment of disease

Country Status (13)

Country Link
EP (1) EP1109506A4 (en)
JP (1) JP2002522111A (en)
KR (1) KR20010072307A (en)
CN (1) CN1132557C (en)
AR (1) AR021750A1 (en)
AU (1) AU750633B2 (en)
BR (1) BR9912773A (en)
CA (1) CA2339384C (en)
HK (1) HK1039555B (en)
IL (1) IL141273A0 (en)
MX (1) MXPA01001336A (en)
TW (1) TW396030B (en)
WO (1) WO2000007515A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7390668B2 (en) * 1996-10-30 2008-06-24 Provectus Pharmatech, Inc. Intracorporeal medicaments for photodynamic treatment of disease
US6493570B1 (en) * 1998-11-02 2002-12-10 Photogen, Inc. Method for improved imaging and photodynamic therapy
CN1372467A (en) * 1999-08-13 2002-10-02 福托金公司 Improved topical medicaments and methods for photodynamic treatment of disease
WO2003084601A2 (en) * 2002-04-02 2003-10-16 Lumerx, Inc. Apparatus and methods using visible light for debilitating and/or killing microorganisms within the body
US20050053895A1 (en) 2003-09-09 2005-03-10 The Procter & Gamble Company Attention: Chief Patent Counsel Illuminated electric toothbrushes emitting high luminous intensity toothbrush
EP1541091A1 (en) * 2003-12-10 2005-06-15 EL.EN. S.p.A. Device for treating tumors by laser thermotherapy
US20080045859A1 (en) * 2006-08-19 2008-02-21 Fritsch Michael H Devices and Methods for In-Vivo Pathology Diagnosis
KR20090108069A (en) * 2007-01-09 2009-10-14 헬스 리서치 인코포레이티드 Treatment of Barrett's Esophagus with Photodynamic Therapy
DE102008047640B4 (en) * 2008-09-17 2012-10-25 Anton Kasenbacher Use of a laser processing device for ablation of tooth material
WO2011097458A2 (en) * 2010-02-04 2011-08-11 University Of Rochester Devices and methods for conforming photodynamic therapy to specific anatomic locations
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
WO2015009992A1 (en) 2013-07-18 2015-01-22 The General Hospital Corporation Vessel treatment systems, methods, and kits
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
US10292381B2 (en) 2012-07-20 2019-05-21 The General Hospital Corporation Vessel treatment systems, methods, and kits
EP2903572B1 (en) * 2012-10-08 2019-05-15 Universität Leipzig A device for a medical treatment of a sclera
AU2014233300B2 (en) * 2013-03-15 2018-04-05 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
DE102015225400A1 (en) * 2015-12-16 2017-06-22 Vimecon Gmbh Swiveling ablation catheter
CN107376132B (en) * 2017-07-17 2020-02-04 尚华 Novel optical fiber catheter and preparation method thereof
CN107213554B (en) * 2017-07-17 2019-11-19 尚华 A kind of liquid light conduction device of intervention

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5940830A (en) * 1982-08-31 1984-03-06 浜松ホトニクス株式会社 Apparatus for diagnosis of cancer using laser beam pulse
JPS63111886A (en) * 1986-10-29 1988-05-17 呉羽化学工業株式会社 Cancer remedy apparatus using optical diode
US5346670A (en) * 1986-12-24 1994-09-13 British Technology Group U.S.A. Inc. Phthalocyanine and tetrabenztriazaporphyrin reagents
US4973848A (en) * 1989-07-28 1990-11-27 J. Mccaughan Laser apparatus for concurrent analysis and treatment
US5034613A (en) * 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5576013A (en) * 1995-03-21 1996-11-19 Eastern Virginia Medical School Treating vascular and neoplastic tissues
IT1275571B (en) * 1995-07-19 1997-08-07 Consiglio Nazionale Ricerche FLUOROGENIC SUBSTRATES SUSCEPTIBLE FOR PHOTOACTIVATION AFTER ENZYMATIC TRANSFORMATION SUITABLE FOR DIAGNOSIS AND PHOTODYNAMIC CANCER THERAPY
US5797868A (en) * 1996-07-25 1998-08-25 Cordis Corporation Photodynamic therapy balloon catheter
US5814008A (en) * 1996-07-29 1998-09-29 Light Sciences Limited Partnership Method and device for applying hyperthermia to enhance drug perfusion and efficacy of subsequent light therapy
US5829448A (en) 1996-10-30 1998-11-03 Photogen, Inc. Method for improved selectivity in photo-activation of molecular agents
US20010003800A1 (en) * 1996-11-21 2001-06-14 Steven J. Frank Interventional photonic energy emitter system
US5827269A (en) * 1996-12-31 1998-10-27 Gynecare, Inc. Heated balloon having a reciprocating fluid agitator

Also Published As

Publication number Publication date
EP1109506A1 (en) 2001-06-27
AU5391799A (en) 2000-02-28
HK1039555A1 (en) 2002-05-03
TW396030B (en) 2000-07-01
EP1109506A4 (en) 2009-09-09
KR20010072307A (en) 2001-07-31
CN1132557C (en) 2003-12-31
JP2002522111A (en) 2002-07-23
MXPA01001336A (en) 2002-04-24
CN1317952A (en) 2001-10-17
HK1039555B (en) 2004-05-07
WO2000007515A1 (en) 2000-02-17
BR9912773A (en) 2001-10-16
CA2339384C (en) 2008-07-08
AR021750A1 (en) 2002-08-07
AU750633B2 (en) 2002-07-25
IL141273A0 (en) 2002-03-10

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MKEX Expiry

Effective date: 20190802