CA2291706C - Procede de preparation d'un greffon osseux composite - Google Patents
Procede de preparation d'un greffon osseux composite Download PDFInfo
- Publication number
- CA2291706C CA2291706C CA002291706A CA2291706A CA2291706C CA 2291706 C CA2291706 C CA 2291706C CA 002291706 A CA002291706 A CA 002291706A CA 2291706 A CA2291706 A CA 2291706A CA 2291706 C CA2291706 C CA 2291706C
- Authority
- CA
- Canada
- Prior art keywords
- bone marrow
- substrate
- cells
- bone
- marrow aspirate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
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- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
Abstract
La présente invention a pour objet un procédé nouveau et amélioré pour préparer un greffon osseux composite. Ce procédé consiste à fournir un produit d'aspiration de moelle osseuse en suspension et à faire passer ce produit à travers un substrat poreux, biocompatible et implantable pour constituer un greffon osseux composite comportant une population enrichie de cellules parentes de tissu conjonctif. Ce procédé peut être mis en oeuvre de manière peropératoire, ce qui réduit le nombre de procédures invasives que doit subir le greffé. L'invention concerne également un greffon osseux composite amélioré préparé selon le présent procédé. Le greffon composite amélioré comprend une population enrichie de cellules parentes de tissu conjonctif et un nombre de cellules parentes de tissu conjonctif par volume unitaire supérieur à celui observé dans le produit d'aspiration de moelle osseuse initial. La présente invention concerne également une trousse comprenant l'appareil utilisé pour préparer le greffon osseux composite.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/675,498 | 1996-07-03 | ||
| US08/675,498 US5824084A (en) | 1996-07-03 | 1996-07-03 | Method of preparing a composite bone graft |
| PCT/US1997/016514 WO1998000174A2 (fr) | 1996-07-03 | 1997-07-03 | Procede de preparation d'un greffon osseux composite |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2291706A1 CA2291706A1 (fr) | 1998-01-08 |
| CA2291706C true CA2291706C (fr) | 2006-08-29 |
Family
ID=24710768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002291706A Expired - Lifetime CA2291706C (fr) | 1996-07-03 | 1997-07-03 | Procede de preparation d'un greffon osseux composite |
Country Status (3)
| Country | Link |
|---|---|
| AT (1) | ATE499119T1 (fr) |
| CA (1) | CA2291706C (fr) |
| DE (1) | DE69740129D1 (fr) |
-
1997
- 1997-07-03 CA CA002291706A patent/CA2291706C/fr not_active Expired - Lifetime
- 1997-07-03 AT AT97941082T patent/ATE499119T1/de not_active IP Right Cessation
- 1997-07-03 DE DE69740129T patent/DE69740129D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69740129D1 (de) | 2011-04-07 |
| ATE499119T1 (de) | 2011-03-15 |
| CA2291706A1 (fr) | 1998-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20170704 |