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CA2237704A1 - Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter - Google Patents

Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter Download PDF

Info

Publication number
CA2237704A1
CA2237704A1 CA 2237704 CA2237704A CA2237704A1 CA 2237704 A1 CA2237704 A1 CA 2237704A1 CA 2237704 CA2237704 CA 2237704 CA 2237704 A CA2237704 A CA 2237704A CA 2237704 A1 CA2237704 A1 CA 2237704A1
Authority
CA
Canada
Prior art keywords
protein
caulobacter
layer
fusion protein
cleavage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2237704
Other languages
English (en)
Inventor
John Smit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Priority to CA 2237704 priority Critical patent/CA2237704A1/fr
Priority to PCT/CA1999/000637 priority patent/WO2000004170A1/fr
Priority to EP99928972A priority patent/EP1097227A1/fr
Priority to JP2000560267A priority patent/JP2002520060A/ja
Priority to AU45973/99A priority patent/AU4597399A/en
Priority to CA002334080A priority patent/CA2334080A1/fr
Publication of CA2237704A1 publication Critical patent/CA2237704A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/10011—Birnaviridae
    • C12N2720/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA 2237704 1998-07-14 1998-07-14 Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter Abandoned CA2237704A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA 2237704 CA2237704A1 (fr) 1998-07-14 1998-07-14 Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter
PCT/CA1999/000637 WO2000004170A1 (fr) 1998-07-14 1999-07-14 Clivage de proteines hybrides de recombinaison obtenues a partir de colobacter
EP99928972A EP1097227A1 (fr) 1998-07-14 1999-07-14 Clivage de proteines hybrides contenant une partie d'une proteine s-layer de caulobacter
JP2000560267A JP2002520060A (ja) 1998-07-14 1999-07-14 カウロバクター（Ｃａｕｌｏｂａｃｔｅｒ）が産生した組換え融合タンパク質の切断
AU45973/99A AU4597399A (en) 1998-07-14 1999-07-14 Cleavage of caulobacter produced recombinant fusion proteins
CA002334080A CA2334080A1 (fr) 1998-07-14 1999-07-14 Clivage de proteines hybrides de recombinaison obtenues a partir de colobacter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2237704 CA2237704A1 (fr) 1998-07-14 1998-07-14 Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter

Publications (1)

Publication Number Publication Date
CA2237704A1 true CA2237704A1 (fr) 2000-01-14

Family

ID=4162433

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2237704 Abandoned CA2237704A1 (fr) 1998-07-14 1998-07-14 Clivage des proteines recombinantes hybrides obtenues a partir du caulobacter

Country Status (5)

Country Link
EP (1) EP1097227A1 (fr)
JP (1) JP2002520060A (fr)
AU (1) AU4597399A (fr)
CA (1) CA2237704A1 (fr)
WO (1) WO2000004170A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19603649A1 (de) * 1996-02-01 1997-08-07 Werner Lubitz Rekombinante Expression von S-Layer-Proteinen
WO2003102187A1 (fr) * 2002-05-31 2003-12-11 Scegen Pty Ltd Proteines chimeres auto-coalescentes ou auto-agglomerantes derivees d'une sequence de translocation membranaire
CA2583113C (fr) * 2004-10-05 2015-11-10 Diversa Corporation Compositions comprenant un antigene et un epitope t de promiscuite
US8609621B2 (en) 2010-11-15 2013-12-17 E I Du Pont De Nemours And Company Acid-cleavable linkers exhibiting altered rates of acid hydrolysis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034000A1 (fr) * 1992-06-09 1997-09-18 The University Of British Columbia Expression et secretion de polypeptides heterologues a partir de colobacter
CA2090549C (fr) * 1992-06-09 2008-01-15 John Smit Expression d'une proteine de surface d'origine bacterienne

Also Published As

Publication number Publication date
EP1097227A1 (fr) 2001-05-09
WO2000004170A1 (fr) 2000-01-27
JP2002520060A (ja) 2002-07-09
AU4597399A (en) 2000-02-07

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Legal Events

Date Code Title Description
FZDE Dead