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CA2185511A1 - Cytological specimen analysis system with individualized patient data - Google Patents

Cytological specimen analysis system with individualized patient data

Info

Publication number
CA2185511A1
CA2185511A1 CA002185511A CA2185511A CA2185511A1 CA 2185511 A1 CA2185511 A1 CA 2185511A1 CA 002185511 A CA002185511 A CA 002185511A CA 2185511 A CA2185511 A CA 2185511A CA 2185511 A1 CA2185511 A1 CA 2185511A1
Authority
CA
Canada
Prior art keywords
cells
analysis
specimen
cytological
analysis system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002185511A
Other languages
French (fr)
Other versions
CA2185511C (en
Inventor
Vladimir Dadeshidze
Richard A. Domanik
Peter G. Gombrich
Lars J. Olsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MonoGen Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2185511A1 publication Critical patent/CA2185511A1/en
Application granted granted Critical
Publication of CA2185511C publication Critical patent/CA2185511C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Multimedia (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A cytological screening system assists a cytotechnologist to determine the presence of "abnormal" cells in a cytological specimen. The system includes a microscope with a motorized stage, autofocus lens, video camera and image capturing and image analysis systems. The specimen is scanned, and cells with characteristics falling outside ranges determined by the system specifically for the specimen are marked for analysis. Analysis is performed by utilizing a set of weighted characteristics, which are based in part of the individual medical history of the patient. Cells with a combination of characteristics which fall outside a predetermined range are determined to be abnormal and are identified for further analysis by the cytotechnologist. Alternatively, the system provides relational information and reference material during the manual screening process.
CA002185511A 1995-09-15 1996-09-13 Cytological specimen analysis system with individualized patient data Expired - Fee Related CA2185511C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52922095A 1995-09-15 1995-09-15
US08/529,220 1995-09-15

Publications (2)

Publication Number Publication Date
CA2185511A1 true CA2185511A1 (en) 1997-03-16
CA2185511C CA2185511C (en) 2008-08-05

Family

ID=24109008

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002185511A Expired - Fee Related CA2185511C (en) 1995-09-15 1996-09-13 Cytological specimen analysis system with individualized patient data

Country Status (3)

Country Link
CA (1) CA2185511C (en)
DE (1) DE19637741B4 (en)
GB (1) GB2305723B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19916749B4 (en) * 1999-04-14 2004-02-12 Carl Zeiss Jena Gmbh Procedure for examining samples
DK2156370T3 (en) 2007-05-14 2012-01-23 Historx Inc Compartment separation by pixel characterization using image data clustering
EP2162728B1 (en) 2007-06-15 2016-07-27 Novartis AG Microscope system and method for obtaining standardized sample data
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
US7978258B2 (en) 2007-08-31 2011-07-12 Historx, Inc. Automatic exposure time selection for imaging tissue
US9240043B2 (en) 2008-09-16 2016-01-19 Novartis Ag Reproducible quantification of biomarker expression

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1439986A (en) * 1973-08-22 1976-06-16 Inst Elektroniki I Vychesletel Medical diagnostic apparatus
US4175860A (en) * 1977-05-31 1979-11-27 Rush-Presbyterian-St. Luke's Medical Center Dual resolution method and apparatus for use in automated classification of pap smear and other samples
US4965725B1 (en) * 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
WO1991006911A1 (en) * 1989-10-23 1991-05-16 Neuromedical Systems, Inc. Automated cytological specimen classification system and method
CA2064571C (en) * 1990-03-30 2002-08-06 Mark R. Rutenberg Automated cytological specimen classification system and method
US5235522A (en) * 1990-10-10 1993-08-10 Cell Analysis Systems, Inc. Method and apparatus for automated analysis of biological specimens
EP0628186B1 (en) * 1992-02-18 1998-12-09 Neopath, Inc. Method for identifying normal biomedical specimens
CA2132269C (en) * 1993-10-12 2000-02-01 Rainer Hermann Doerrer Interactive automated cytology method and system

Also Published As

Publication number Publication date
DE19637741A1 (en) 1997-04-24
GB9619296D0 (en) 1996-10-30
CA2185511C (en) 2008-08-05
GB2305723A (en) 1997-04-16
DE19637741B4 (en) 2006-05-04
GB2305723B (en) 1999-09-29

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150914