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CA2166479A1 - Density enhanced protein tyrosine phosphatases - Google Patents

Density enhanced protein tyrosine phosphatases

Info

Publication number
CA2166479A1
CA2166479A1 CA002166479A CA2166479A CA2166479A1 CA 2166479 A1 CA2166479 A1 CA 2166479A1 CA 002166479 A CA002166479 A CA 002166479A CA 2166479 A CA2166479 A CA 2166479A CA 2166479 A1 CA2166479 A1 CA 2166479A1
Authority
CA
Canada
Prior art keywords
protein tyrosine
tyrosine phosphatases
enhanced protein
disclosed
dep
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002166479A
Other languages
French (fr)
Other versions
CA2166479C (en
Inventor
Nicholas K. Tonks
Arnie Ostman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cold Spring Harbor Laboratory
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA002537374A priority Critical patent/CA2537374A1/en
Priority claimed from PCT/US1995/005512 external-priority patent/WO1995030008A1/en
Publication of CA2166479A1 publication Critical patent/CA2166479A1/en
Application granted granted Critical
Publication of CA2166479C publication Critical patent/CA2166479C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Novel Type III density enhanced protein tyrosine phosphatases are disclosed and exemplified by human DEP-1 enzyme. Polynucleotides, encoding huDEP-1 are disclosed, along with methods and materials for production of the same by recombinant procedures. Binding molecules specific for DEP-1 are also disclosed as useful for modulating the biological activities of DEP-1.
CA002166479A 1994-05-03 1995-05-03 Density enhanced protein tyrosine phosphatases Expired - Lifetime CA2166479C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002537374A CA2537374A1 (en) 1994-05-03 1995-05-03 Density enhanced protein tyrosine phosphatases

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23794094A 1994-05-03 1994-05-03
US08/237,940 1994-05-03
PCT/US1995/005512 WO1995030008A1 (en) 1994-05-03 1995-05-03 Density enhanced protein tyrosine phosphatases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002537374A Division CA2537374A1 (en) 1994-05-03 1995-05-03 Density enhanced protein tyrosine phosphatases

Publications (2)

Publication Number Publication Date
CA2166479A1 true CA2166479A1 (en) 1995-11-09
CA2166479C CA2166479C (en) 2007-02-06

Family

ID=37734812

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002166479A Expired - Lifetime CA2166479C (en) 1994-05-03 1995-05-03 Density enhanced protein tyrosine phosphatases

Country Status (1)

Country Link
CA (1) CA2166479C (en)

Also Published As

Publication number Publication date
CA2166479C (en) 2007-02-06

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Legal Events

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Effective date: 20150504