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CA2163878A1 - Agents renfermant un compose possedant un effet antiandrogene et un compose a effet competitif, antagoniste de la progesterone - Google Patents

Agents renfermant un compose possedant un effet antiandrogene et un compose a effet competitif, antagoniste de la progesterone

Info

Publication number
CA2163878A1
CA2163878A1 CA 2163878 CA2163878A CA2163878A1 CA 2163878 A1 CA2163878 A1 CA 2163878A1 CA 2163878 CA2163878 CA 2163878 CA 2163878 A CA2163878 A CA 2163878A CA 2163878 A1 CA2163878 A1 CA 2163878A1
Authority
CA
Canada
Prior art keywords
alpha
beta
hydroxy
compound
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2163878
Other languages
English (en)
Inventor
Horst Michna
Martin Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2163878A1 publication Critical patent/CA2163878A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Des agents contiennent au moins un composé à action anti-androgène (AA) ainsi qu'au moins un composé à action compétitive antagoniste de la progestérone (AP). Ces agents sont utiles pour préparer des médicaments pour la prophylaxie et la thérapie de carcinomes de la prostate ainsi que de l'hyperplasie bénigne de la prostate (HBP). L'invention concerne en outre l'utilisation d'au moins un composé à action AP afin de préparer des médicaments pour la prophylaxie et la prévention de l'HBP.
CA 2163878 1993-05-28 1994-05-30 Agents renfermant un compose possedant un effet antiandrogene et un compose a effet competitif, antagoniste de la progesterone Abandoned CA2163878A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4318371.9 1993-05-28
DE19934318371 DE4318371A1 (de) 1993-05-28 1993-05-28 Mittel, enthaltend eine Verbindung mit antiandrogener sowie eine Verbindung mit kompetitiver, progesteronantagonistischer Wirkung

Publications (1)

Publication Number Publication Date
CA2163878A1 true CA2163878A1 (fr) 1994-12-08

Family

ID=6489489

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2163878 Abandoned CA2163878A1 (fr) 1993-05-28 1994-05-30 Agents renfermant un compose possedant un effet antiandrogene et un compose a effet competitif, antagoniste de la progesterone

Country Status (5)

Country Link
EP (1) EP0701445A1 (fr)
AU (1) AU6998494A (fr)
CA (1) CA2163878A1 (fr)
DE (1) DE4318371A1 (fr)
WO (1) WO1994027610A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0748220A4 (fr) * 1994-01-21 1997-09-10 Sepracor Inc Procedes et compositions de traitement de maladies dependantes des androgenes a l'aide de r-(-)-casodex optiquement pur
DE19825591A1 (de) * 1998-06-09 1999-12-23 Jenapharm Gmbh Pharmazeutische Kombinationen zum Ausgleich eines Testosteron-Defizits beim Mann mit gleichzeitigem Schutz der Prostata
UY27301A1 (es) * 2001-05-25 2003-02-28 Schering Ag Uso y composiciones de antiprogestinas para el tratamiento de enfermedades de la próstata
SE0103838D0 (sv) * 2001-11-16 2001-11-16 Astrazeneca Ab Pharmaceutical formulation & product

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5851690A (en) * 1989-07-07 1991-02-06 Endorecherche Inc. Method of treatment of androgen-related diseases
DE4039561A1 (de) * 1990-12-07 1992-07-09 Schering Ag Verwendung von antigestagenen zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
AU6998494A (en) 1994-12-20
WO1994027610A1 (fr) 1994-12-08
EP0701445A1 (fr) 1996-03-20
DE4318371A1 (de) 1994-12-01

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Legal Events

Date Code Title Description
FZDE Dead