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CA2153975A1 - Marker for crohn's disease and multiple sclerosis - Google Patents

Marker for crohn's disease and multiple sclerosis

Info

Publication number
CA2153975A1
CA2153975A1 CA 2153975 CA2153975A CA2153975A1 CA 2153975 A1 CA2153975 A1 CA 2153975A1 CA 2153975 CA2153975 CA 2153975 CA 2153975 A CA2153975 A CA 2153975A CA 2153975 A1 CA2153975 A1 CA 2153975A1
Authority
CA
Canada
Prior art keywords
crohn
marker
disease
multiple sclerosis
circulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2153975
Other languages
French (fr)
Other versions
CA2153975C (en
Inventor
Bruce Yacyshyn
Linda M. Pilarski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2153975A1 publication Critical patent/CA2153975A1/en
Application granted granted Critical
Publication of CA2153975C publication Critical patent/CA2153975C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/285—Demyelinating diseases; Multipel sclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Increased expression of the antigen CD45RO on circulating B cells has been identified as a marker of Crohn's disease and multiple sclerosis.
CA 2153975 1993-11-15 1994-11-15 Marker for crohn's disease and multiple sclerosis Expired - Fee Related CA2153975C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9323542.2 1993-11-15
GB939323542A GB9323542D0 (en) 1993-11-15 1993-11-15 Lymphocyte marker specific for corhn's disease

Publications (2)

Publication Number Publication Date
CA2153975A1 true CA2153975A1 (en) 1995-05-26
CA2153975C CA2153975C (en) 1999-03-23

Family

ID=10745201

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2153975 Expired - Fee Related CA2153975C (en) 1993-11-15 1994-11-15 Marker for crohn's disease and multiple sclerosis

Country Status (5)

Country Link
EP (1) EP0679258A1 (en)
JP (1) JPH08508572A (en)
CA (1) CA2153975C (en)
GB (1) GB9323542D0 (en)
WO (1) WO1995014230A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024957A (en) * 1993-06-02 2000-02-15 Research Corporation Technologies, Inc. Immunomodulators and methods for the prevention and reversal of organ transplant rejection using same
US6106834A (en) * 1993-06-02 2000-08-22 Research Corporation Technologies, Inc. Use of anti-CD45 leukocyte antigen antibodies for immunomodulation
IL146005A0 (en) 1999-05-07 2002-07-25 Genentech Inc Treatment of autoimmune diseases with antagonists which bind to b cell surface markers

Also Published As

Publication number Publication date
CA2153975C (en) 1999-03-23
EP0679258A1 (en) 1995-11-02
GB9323542D0 (en) 1994-01-05
JPH08508572A (en) 1996-09-10
WO1995014230A1 (en) 1995-05-26

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed