CA2113573A1 - Modulation et diagnostic des dysfonctions a cytokines - Google Patents

Modulation et diagnostic des dysfonctions a cytokines

Info

Publication number: CA2113573A1
Authority: CA; Canada
Prior art keywords: lock; dsrna; cytokine; mismatched; mismatched dsrna
Prior art date: 1991-07-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002113573A

Other languages

English (en)

Inventor

William Carter

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

HEM Pharmaceuticals Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-16

Filing date

1992-06-23

Publication date

1993-02-04

1992-06-23 Application filed by Individual filed Critical Individual

1993-02-04 Publication of CA2113573A1 publication Critical patent/CA2113573A1/fr

Status Abandoned legal-status Critical Current

Links

102000004127 Cytokines Human genes 0.000 title claims abstract description 20
108090000695 Cytokines Proteins 0.000 title claims abstract description 20
230000004064 dysfunction Effects 0.000 title claims 2
238000003745 diagnosis Methods 0.000 title 1
108091032973 (ribonucleotides)n+m Proteins 0.000 claims abstract description 31
102000040650 (ribonucleotides)n+m Human genes 0.000 claims abstract description 21
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208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 4
238000000034 method Methods 0.000 claims description 12
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108010063738 Interleukins Proteins 0.000 claims description 2
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DNXHEGUUPJUMQT-UHFFFAOYSA-N (+)-estrone Natural products OC1=CC=C2C3CCC(C)(C(CC4)=O)C4C3CCC2=C1 DNXHEGUUPJUMQT-UHFFFAOYSA-N 0.000 description 1
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LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
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102000010789 Interleukin-2 Receptors Human genes 0.000 description 1
108010038453 Interleukin-2 Receptors Proteins 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)
Eye Examination Apparatus (AREA)

CA002113573A 1991-07-16 1992-06-23 Modulation et diagnostic des dysfonctions a cytokines Abandoned CA2113573A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US73022991A	1991-07-16	1991-07-16
US730,229		1991-07-16

Publications (1)

Publication Number	Publication Date
CA2113573A1 true CA2113573A1 (fr)	1993-02-04

Family

ID=24934492

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002113573A Abandoned CA2113573A1 (fr)	1991-07-16	1992-06-23	Modulation et diagnostic des dysfonctions a cytokines

Country Status (11)

Country	Link
EP (1)	EP0596912A4 (fr)
JP (1)	JPH07501787A (fr)
CN (1)	CN1068738A (fr)
AU (1)	AU2268892A (fr)
CA (1)	CA2113573A1 (fr)
IE (1)	IE922145A1 (fr)
MX (1)	MX9204164A (fr)
PT (1)	PT100688A (fr)
TW (1)	TW271398B (fr)
WO (1)	WO1993001717A1 (fr)
ZA (1)	ZA925263B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE48948E1 (en)	2008-04-18	2022-03-01	Warsaw Orthopedic, Inc.	Clonidine compounds in a biodegradable polymer
US20100239632A1 (en)	2009-03-23	2010-09-23	Warsaw Orthopedic, Inc.	Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4795744A (en) *	1986-07-17	1989-01-03	Hem Research, Inc.	Modulation of AIDS virus-related events by double-stranded RNAS
US4950652A (en) *	1987-03-23	1990-08-21	Hem Research, Inc.	dsRNAs for combination therapy in the treatment of viral diseases
AU1820388A (en) *	1987-07-17	1989-01-19	Hem Research, Inc.	Double stranded rna correction of aberrant metabolic pathways associated with uncontrolled tumor cell and virus growth cycles
AU1820588A (en) *	1987-07-17	1989-01-19	Hem Research, Inc.	Double-stranded rna correction of abnormalities in circulating immune complexes and monocyte function
CA1320446C (fr) *	1988-06-20	1993-07-20	William A. Carter	Modulation d'etats cellulaires resistant a la lymphokine a l'aide de dsarn

1992
- 1992-06-23 CA CA002113573A patent/CA2113573A1/fr not_active Abandoned
- 1992-06-23 AU AU22688/92A patent/AU2268892A/en not_active Abandoned
- 1992-06-23 JP JP5502798A patent/JPH07501787A/ja active Pending
- 1992-06-23 WO PCT/US1992/005286 patent/WO1993001717A1/fr not_active Application Discontinuation
- 1992-06-23 EP EP19920914799 patent/EP0596912A4/en not_active Withdrawn
- 1992-07-01 IE IE214592A patent/IE922145A1/en not_active Application Discontinuation
- 1992-07-15 TW TW081105601A patent/TW271398B/zh active
- 1992-07-15 MX MX9204164A patent/MX9204164A/es unknown
- 1992-07-15 ZA ZA925263A patent/ZA925263B/xx unknown
- 1992-07-15 CN CN92105778A patent/CN1068738A/zh active Pending
- 1992-07-15 PT PT100688A patent/PT100688A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0596912A1 (fr)	1994-05-18
TW271398B (fr)	1996-03-01
MX9204164A (es)	1993-05-01
CN1068738A (zh)	1993-02-10
AU2268892A (en)	1993-02-23
IE922145A1 (en)	1993-01-27
EP0596912A4 (en)	1994-07-27
WO1993001717A1 (fr)	1993-02-04
JPH07501787A (ja)	1995-02-23
PT100688A (pt)	1993-10-29
ZA925263B (en)	1993-03-31

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Miller et al.	1999	Review article imiquimod applied topically: a novel immune response modifier and new class of drug
CN1098103C (zh)	2003-01-08	交感人类白细胞干扰素的制药用途
KAUFMAN et al.	1990	L-Tryptophan-associated eosinophilic perimyositis, neuritis, and fasciitis: a clinicopathologic and laboratory study of 25 patients
CN1190198C (zh)	2005-02-23	激活的T淋巴细胞中Ribavirin 和Ribavirin类似物对TH1/TH2细胞因子表达的调控
JP2000510122A (ja)	2000-08-08	低用量ｉｌ―２による免疫応答の刺激
Tsokos et al.	1986	Deficient γ‐interferon production in patients with systemic lupus erythematosus
Hansen et al.	2011	IFN-α primes T-and NK-cells for IL-15-mediated signaling and cytotoxicity
KR960008009B1 (ko)	1996-06-19	인터류킨 및 이중-가닥 rna를 포함하는 상승작용화 조성물
EP0347501A1 (fr)	1989-12-27	Modulation de la résistance aux lymphokines de certains états cellulaires par un ARN bicatenaire
EP0994702B1 (fr)	2003-03-12	Composition contenant un nucleotide
JPH01104015A (ja)	1989-04-21	二本鎖ｒｎａを含有する医薬
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