CA2092906A1 - Analogues stabilises de la grf - Google Patents
Analogues stabilises de la grfInfo
- Publication number
- CA2092906A1 CA2092906A1 CA002092906A CA2092906A CA2092906A1 CA 2092906 A1 CA2092906 A1 CA 2092906A1 CA 002092906 A CA002092906 A CA 002092906A CA 2092906 A CA2092906 A CA 2092906A CA 2092906 A1 CA2092906 A1 CA 2092906A1
- Authority
- CA
- Canada
- Prior art keywords
- val
- ala
- ile
- ser
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 125000003588 lysine group Chemical class [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
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- 229910052751 metal Chemical class 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 108010053118 myohemerythrin Proteins 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 201000002528 pancreatic cancer Diseases 0.000 description 1
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- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
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- 239000003016 pheromone Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- 230000003248 secreting effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- YRALAIOMGQZKOW-UHFFFAOYSA-N sulfated caerulein Natural products C=1C=CC=CC=1CC(C(N)=O)NC(=O)C(CC(O)=O)NC(=O)C(CCSC)NC(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)CNC(=O)C(C(C)O)NC(=O)C(NC(=O)C(CC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C1NC(=O)CC1)CC1=CC=C(OS(O)(=O)=O)C=C1 YRALAIOMGQZKOW-UHFFFAOYSA-N 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 150000003511 tertiary amides Chemical class 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 230000001810 trypsinlike Effects 0.000 description 1
- 239000012808 vapor phase Substances 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Amplifiers (AREA)
- Tires In General (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Detergent Compositions (AREA)
- General Preparation And Processing Of Foods (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61417090A | 1990-11-14 | 1990-11-14 | |
US614,170 | 1990-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2092906A1 true CA2092906A1 (fr) | 1992-05-15 |
Family
ID=24460133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002092906A Abandoned CA2092906A1 (fr) | 1990-11-14 | 1991-11-13 | Analogues stabilises de la grf |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0565536A1 (fr) |
JP (1) | JPH06502650A (fr) |
AU (1) | AU655791B2 (fr) |
CA (1) | CA2092906A1 (fr) |
CZ (1) | CZ85393A3 (fr) |
FI (1) | FI932185L (fr) |
HU (1) | HUT63857A (fr) |
NO (1) | NO931745D0 (fr) |
RU (1) | RU2119800C1 (fr) |
SK (1) | SK49093A3 (fr) |
WO (1) | WO1992008481A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9906715D0 (en) * | 1999-03-23 | 1999-05-19 | Ferring Bv | Compositions for promoting growth |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4689318A (en) * | 1985-08-29 | 1987-08-25 | The Salk Institute For Biological Studies | GRF analogs |
DK0477217T3 (da) * | 1989-06-16 | 1995-04-03 | Upjohn Co | Stabiliserede, potente GRF-analoge |
-
1991
- 1991-11-13 SK SK49093A patent/SK49093A3/sk unknown
- 1991-11-13 JP JP4501877A patent/JPH06502650A/ja not_active Withdrawn
- 1991-11-13 RU RU93032314A patent/RU2119800C1/ru active
- 1991-11-13 CA CA002092906A patent/CA2092906A1/fr not_active Abandoned
- 1991-11-13 AU AU90551/91A patent/AU655791B2/en not_active Ceased
- 1991-11-13 EP EP92900732A patent/EP0565536A1/fr not_active Withdrawn
- 1991-11-13 WO PCT/US1991/008248 patent/WO1992008481A1/fr not_active Application Discontinuation
- 1991-11-13 CZ CS93853A patent/CZ85393A3/cs unknown
- 1991-11-13 HU HU931385A patent/HUT63857A/hu unknown
-
1993
- 1993-05-13 FI FI932185A patent/FI932185L/fi not_active Application Discontinuation
- 1993-05-13 NO NO931745A patent/NO931745D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP0565536A1 (fr) | 1993-10-20 |
HU9301385D0 (en) | 1993-09-28 |
FI932185A0 (fi) | 1993-05-13 |
HUT63857A (en) | 1993-10-28 |
CZ85393A3 (en) | 1994-03-16 |
RU2119800C1 (ru) | 1998-10-10 |
NO931745L (no) | 1993-05-13 |
SK49093A3 (en) | 1993-10-06 |
WO1992008481A1 (fr) | 1992-05-29 |
NO931745D0 (no) | 1993-05-13 |
FI932185L (fi) | 1993-05-13 |
AU655791B2 (en) | 1995-01-12 |
JPH06502650A (ja) | 1994-03-24 |
AU9055191A (en) | 1992-06-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |