CA2087190A1 - Analogues de l'hormone parathyroide modifies aux positions 3, 6 ou 9 - Google Patents

Analogues de l'hormone parathyroide modifies aux positions 3, 6 ou 9

Info

Publication number: CA2087190A1
Authority: CA; Canada
Prior art keywords: amino acid; pharmaceutical composition; serine; bpth; ser
Prior art date: 1990-07-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002087190A

Other languages

English (en)

Inventor

Fred E. Cohen

Robert A. Nissenson

Gordon J. Strewler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of California San Diego UCSD

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-13

Filing date

1991-07-15

Publication date

1992-01-14

1991-07-15 Application filed by Individual filed Critical Individual

1992-01-14 Publication of CA2087190A1 publication Critical patent/CA2087190A1/fr

Status Abandoned legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

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Health & Medical Sciences (AREA)
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Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Biophysics (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

CA002087190A 1990-07-13 1991-07-15 Analogues de l'hormone parathyroide modifies aux positions 3, 6 ou 9 Abandoned CA2087190A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US55376090A	1990-07-13	1990-07-13
US553,760		1990-07-13

Publications (1)

Publication Number	Publication Date
CA2087190A1 true CA2087190A1 (fr)	1992-01-14

Family

ID=24210645

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002087190A Abandoned CA2087190A1 (fr)	1990-07-13	1991-07-15	Analogues de l'hormone parathyroide modifies aux positions 3, 6 ou 9

Country Status (5)

Country	Link
EP (1)	EP0539491A1 (fr)
JP (1)	JPH05509098A (fr)
AU (1)	AU667662B2 (fr)
CA (1)	CA2087190A1 (fr)
WO (1)	WO1992000753A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5434246A (en) *	1992-03-19	1995-07-18	Takeda Chemical Industries, Ltd.	Parathyroid hormone derivatives
US5814603A (en) *	1992-06-12	1998-09-29	Affymax Technologies N.V.	Compounds with PTH activity
US5589452A (en) *	1992-07-14	1996-12-31	Syntex (U.S.A.) Inc.	Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5977070A (en) *	1992-07-14	1999-11-02	Piazza; Christin Teresa	Pharmaceutical compositions for the nasal delivery of compounds useful for the treatment of osteoporosis
US6235288B1 (en)	1992-08-26	2001-05-22	The Scripps Research Institute	Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
US5840688A (en) *	1994-03-22	1998-11-24	Research Corporation Technologies, Inc.	Eating suppressant peptides
CO4410206A1 (es) *	1994-07-28	1997-01-09	Sandoz Ag	DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
US6117455A (en)	1994-09-30	2000-09-12	Takeda Chemical Industries, Ltd.	Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
CA2178894A1 (fr) *	1995-06-15	1996-12-16	Tsunehiko Fukuda	Derives de la parathormone et leur utilisation
ATE219374T1 (de)	1996-02-01	2002-07-15	Chugai Pharmaceutical Co Ltd	Medikamente für die behandlung oder vorbeugung von thrombocytopenie
EP0813887A3 (fr) *	1996-06-20	1999-11-03	Hisamitsu Pharmaceutical Co. Inc.	Appareil d'ionophorèse
TW505654B (en) *	1996-07-30	2002-10-11	Hoffmann La Roche	Synthesis of analogs of PTH and PTHrP
CN100335501C (zh)	1996-09-26	2007-09-05	中外制药株式会社	抗人副甲状腺激素相关蛋白的抗体
CN1329080C (zh) *	1997-05-15	2007-08-01	中外制药株式会社	恶病质的治疗剂
TWI234464B (en) *	1998-06-26	2005-06-21	Chugai Pharmaceutical Co Ltd	Medicine constituents for hypercalcemic crisis
TWI255718B (en) *	1999-07-02	2006-06-01	Chugai Pharmaceutical Co Ltd	Ameliorative agent for low vasopressin concentration
WO2001002011A1 (fr) *	1999-07-02	2001-01-11	Chugai Seiyaku Kabushiki Kaisha	REMEDES CONTRE LES MALADIES CAUSEES PAR PTH OU PTHrP
AU5849700A (en) *	1999-07-06	2001-01-22	Chugai Seiyaku Kabushiki Kaisha	Remedies for drug-resistant hypercalcemia
US20030049211A1 (en) *	2000-01-25	2003-03-13	Atsuhiko Kato	Remedies and preventives for dental diseases
CA2401357A1 (fr) *	2000-02-28	2001-09-07	Chugai Seiyaku Kabushiki Kaisha	Agent inhibiteur de decomposition de tissu
EP1987842A1 (fr)	2000-04-28	2008-11-05	Chugai Seiyaku Kabushiki Kaisha	Inhibiteur de la prolifération cellulaire
EP1531855A4 (fr)	2002-01-10	2009-07-22	Osteotrophin Llc	Traitement des affections osseuses avec des medicaments anabolisants du squelette

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3886132A (en) *	1972-12-21	1975-05-27	Us Health	Human parathyroid hormone
US4508828A (en) *	1983-03-21	1985-04-02	Immuno Nuclear Corporation	Bioassay of parathyroid hormone
US4771124A (en) *	1987-05-26	1988-09-13	Merck & Co., Inc.	Parathyroid hormone antagonists with simplified synthetic methodology
US4968669A (en) *	1988-05-09	1990-11-06	Merck & Co., Inc.	Parathyroid hormone antagonists

1991
- 1991-07-15 CA CA002087190A patent/CA2087190A1/fr not_active Abandoned
- 1991-07-15 AU AU82990/91A patent/AU667662B2/en not_active Ceased
- 1991-07-15 EP EP91913697A patent/EP0539491A1/fr not_active Withdrawn
- 1991-07-15 JP JP3513078A patent/JPH05509098A/ja active Pending
- 1991-07-15 WO PCT/US1991/004971 patent/WO1992000753A1/fr not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1992000753A1 (fr)	1992-01-23
AU8299091A (en)	1992-02-04
EP0539491A4 (fr)	1994-03-23
EP0539491A1 (fr)	1993-05-05
JPH05509098A (ja)	1993-12-16
AU667662B2 (en)	1996-04-04

Publication	Publication Date	Title
US5849695A (en)	1998-12-15	Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals
AU667662B2 (en)	1996-04-04	Parathyroid hormone analogues modified at positions 3, 6 or 9
JP4620309B2 (ja)	2011-01-26	骨粗鬆症治療用副甲状腺ホルモン類似体
AU662731B2 (en)	1995-09-14	Growth hormone releasing factor analogs
EP0561412B1 (fr)	1999-02-03	Dérivés d'hormone parathyroide
JP4224111B2 (ja)	2009-02-12	骨粗鬆症の治療のための副甲状腺ホルモン類似体
JPH0532696A (ja)	1993-02-09	副甲状腺ホルモン誘導体
WO2000023594A9 (fr)	2000-10-12	PEPTIDES ET DERIVES PEPTIDIQUES BIOACTIFS DE L'HORMONE PARATHYROIDE (PTH) ET DE LA PROTEINE LIEE A L'HORMONE PARATHYROIDE (PTHrP)
JP3135122B2 (ja)	2001-02-13	ｈＰＴＨフラグメント（１―３７）とその誘導体
US5093233A (en)	1992-03-03	Antagonists with position 13 modification
SK15352000A3 (sk)	2001-04-09	Spôsob výroby cyklických peptidov viazaných k polymérnemu nosiču
JPH1077295A (ja)	1998-03-24	副甲状腺ホルモンおよび副甲状腺ホルモン関連ペプチドのアナログの合成方法
Fournier et al.	1984	Synthesis, conformational studies and biological activities of VIP and related fragments
US6057422A (en)	2000-05-02	Antagonistic analogs of GH-RH inhibiting IGF-I and -II
EP1147133B1 (fr)	2008-08-06	Peptides comprenant une fusion de deux domaines fonctionnels de la PTH par une molecule linker, et leurs dérivés
JPH0725799B2 (ja)	1995-03-22	高カルシウム体液性因子拮抗薬
JPH07113039B2 (ja)	1995-12-06	上皮小体ホルモン拮抗薬
Andreu et al.	1987	Glucagon antagonists: Synthesis and inhibitory properties of Asp3‐containing glucagon analogs
EDE et al.	1994	Synthesis and conformation of constrained peptides with hypoglycaemic activity derived from human growth hormone
US5087562A (en)	1992-02-11	Humoral hypercalcemic factor antagonists with modification at position 13 . . .
HU229220B1 (hu)	2013-09-30	Humán növekedési hormont felszabadító hormon-analógok
US5087561A (en)	1992-02-11	Humoral hypercalcemic factor antagonists modified at position 13 by biotin
Voskamp	1981	Investigations on secretin and analogues
CZ20003999A3 (cs)	2001-05-16	Analog PTH, způsob selektivního navázání na receptor, způsob vyvolání agonistické a antagonistické odezvy, farmaceutický prostředek a způsob léčby

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1999-07-15	FZDE	Dead