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CA2056437A1 - Production d'un virus et purification des proteines de l'enveloppe virale, pour usage dans un vaccin - Google Patents

Production d'un virus et purification des proteines de l'enveloppe virale, pour usage dans un vaccin

Info

Publication number
CA2056437A1
CA2056437A1 CA2056437A CA2056437A CA2056437A1 CA 2056437 A1 CA2056437 A1 CA 2056437A1 CA 2056437 A CA2056437 A CA 2056437A CA 2056437 A CA2056437 A CA 2056437A CA 2056437 A1 CA2056437 A1 CA 2056437A1
Authority
CA
Canada
Prior art keywords
virus
purification
production
envelope proteins
viral envelope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2056437A
Other languages
English (en)
Other versions
CA2056437C (fr
Inventor
Mary Elizabeth Ewasyshyn
Barry Ian Caplan
Anne-Marie Bonneau
Michel Henri Klein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10659282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2056437(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2056437A1 publication Critical patent/CA2056437A1/fr
Application granted granted Critical
Publication of CA2056437C publication Critical patent/CA2056437C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CA002056437A 1989-06-29 1990-06-28 Production d'un virus et purification des proteines de l'enveloppe virale, pour usage dans un vaccin Expired - Lifetime CA2056437C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898914968A GB8914968D0 (en) 1989-06-29 1989-06-29 Production of virus and purification of viral envelope proteins for vaccine use
GB8914968.6 1989-06-29
PCT/CA1990/000205 WO1991000104A1 (fr) 1989-06-29 1990-06-28 Production de virus et purification de proteines d'enveloppes virales pour vaccins

Publications (2)

Publication Number Publication Date
CA2056437A1 true CA2056437A1 (fr) 1990-12-30
CA2056437C CA2056437C (fr) 1996-02-06

Family

ID=10659282

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002056437A Expired - Lifetime CA2056437C (fr) 1989-06-29 1990-06-28 Production d'un virus et purification des proteines de l'enveloppe virale, pour usage dans un vaccin

Country Status (10)

Country Link
US (2) US6455050B1 (fr)
EP (1) EP0480949B2 (fr)
JP (1) JP2599503B2 (fr)
AT (1) ATE130198T1 (fr)
CA (1) CA2056437C (fr)
DE (1) DE69023648T3 (fr)
DK (1) DK0480949T4 (fr)
ES (1) ES2078971T5 (fr)
GB (1) GB8914968D0 (fr)
WO (1) WO1991000104A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69409243T2 (de) 1993-08-06 1998-08-06 Connaught Lab Inaktivierte respiratorische synzytial-virus-impfstoffe
US7223410B1 (en) 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
US6764682B1 (en) * 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
EP0784486B1 (fr) * 1994-10-05 2006-04-05 Vanderbilt University Interleukine-12 utilisee en tant qu'adjuvant pour vaccins contre les paramyxoviridae
US6290971B1 (en) 1995-06-15 2001-09-18 Aventis Pasteur Limited Adjuvant compositions comprising a mineral salt and another immunostimulating compound
CN1285608C (zh) * 1995-09-22 2006-11-22 康诺特实验室有限公司 副流感病毒糖蛋白和疫苗
US6020182A (en) 1996-07-12 2000-02-01 Connaught Laboratories Limited Subunit respiratory syncytial virus vaccine preparation
US7465456B2 (en) 2002-04-26 2008-12-16 Medimmune, Llc Multi plasmid system for the production of influenza virus
DK1499348T3 (en) 2002-04-26 2015-01-05 Medimmune Llc PROCEDURE FOR PREPARING INFECTIOUS INFLUENZA B-VIRA IN CELL CULTURE
CN100582244C (zh) 2003-02-25 2010-01-20 米迪缪尼有限公司 制备流感疫苗组合物的方法
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
JP4771959B2 (ja) 2003-12-23 2011-09-14 メディミューン，エルエルシー インフルエンザウイルス作製のための多重プラスミド系
ES2523587T3 (es) 2007-06-18 2014-11-27 Medimmune, Llc Virus influenza B que tienen alteraciones en el polipéptido hemaglutinina
US11446374B2 (en) 2008-12-09 2022-09-20 Novavax, Inc. Modified RSV F proteins and methods of their use
MX345700B (es) 2008-12-09 2017-02-10 Novavax Inc Proteinas f del vrs modificadas y metodos de uso de las mismas.
CN102985536B (zh) 2010-04-14 2017-12-05 Emd密理博公司 生产高效价、高纯度的病毒母液的方法及使用其的方法
CN114617959A (zh) 2015-09-03 2022-06-14 诺瓦瓦克斯股份有限公司 具有改进的稳定性和免疫原性的疫苗组合物
WO2019023196A1 (fr) 2017-07-24 2019-01-31 Novavax, Inc. Méthodes et compositions pour traiter la maladie respiratoire

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4699785A (en) * 1984-09-18 1987-10-13 The Regents Of The University Of California Cell line producing feline leukemia virus
DE3878468T2 (de) * 1987-12-23 1993-06-09 Upjohn Co Chimarenglykoproteine, enthaltend immunogene segmente des humanen respiratorischen synzytialvirus.
WO1989010405A1 (fr) * 1988-04-22 1989-11-02 The Upjohn Company Glycoproteines chimeriques contenant des segments immunogeniques du virus de la para-influenza humain de type 3

Also Published As

Publication number Publication date
JPH04502410A (ja) 1992-05-07
EP0480949A1 (fr) 1992-04-22
CA2056437C (fr) 1996-02-06
EP0480949B1 (fr) 1995-11-15
DE69023648D1 (de) 1995-12-21
ES2078971T3 (es) 1996-01-01
DK0480949T4 (da) 2004-12-06
ATE130198T1 (de) 1995-12-15
GB8914968D0 (en) 1989-08-23
EP0480949B2 (fr) 2004-08-04
US6306637B1 (en) 2001-10-23
DE69023648T3 (de) 2005-02-03
DE69023648T2 (de) 1996-05-02
WO1991000104A1 (fr) 1991-01-10
DK0480949T3 (da) 1995-12-18
JP2599503B2 (ja) 1997-04-09
ES2078971T5 (es) 2005-03-16
US6455050B1 (en) 2002-09-24

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Legal Events

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