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CA2020168A1 - Process for preparing cis-dihydronopol - Google Patents

Process for preparing cis-dihydronopol

Info

Publication number
CA2020168A1
CA2020168A1 CA2020168A CA2020168A CA2020168A1 CA 2020168 A1 CA2020168 A1 CA 2020168A1 CA 2020168 A CA2020168 A CA 2020168A CA 2020168 A CA2020168 A CA 2020168A CA 2020168 A1 CA2020168 A1 CA 2020168A1
Authority
CA
Canada
Prior art keywords
dihydronopol
esters
preparing cis
cis
platinum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2020168A
Other languages
French (fr)
Other versions
CA2020168C (en
Inventor
Walter Heitmann
Uwe Maetzel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2020168A1 publication Critical patent/CA2020168A1/en
Application granted granted Critical
Publication of CA2020168C publication Critical patent/CA2020168C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/13—Monohydroxylic alcohols containing saturated rings
    • C07C31/137—Monohydroxylic alcohols containing saturated rings polycyclic with condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

A process far preparing cis-dihydronopol and esters thereof in which corresponding esters of (-)nopol are stereoselectively hydrogenated by heterogeneous hydrogenation in the presence of a platinum, platinum oxide or ruthenium/carbon catalyst, and the resulting cis-dihydronopyl esters optionally may be converted into correspanding alcohols by hydrolysis.
CA002020168A 1989-07-07 1990-06-29 Process for preparing cis-dihydronopol Expired - Lifetime CA2020168C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP3922386.8 1989-07-07
DE3922386A DE3922386A1 (en) 1989-07-07 1989-07-07 PROCESS FOR THE PREPARATION OF CIS-DIHYDRONOPOL

Publications (2)

Publication Number Publication Date
CA2020168A1 true CA2020168A1 (en) 1991-01-08
CA2020168C CA2020168C (en) 2000-05-02

Family

ID=6384503

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002020168A Expired - Lifetime CA2020168C (en) 1989-07-07 1990-06-29 Process for preparing cis-dihydronopol

Country Status (12)

Country Link
EP (1) EP0406742B1 (en)
JP (1) JP2807060B2 (en)
AT (1) ATE88456T1 (en)
CA (1) CA2020168C (en)
DD (1) DD297956A5 (en)
DE (2) DE3922386A1 (en)
DK (1) DK0406742T3 (en)
ES (1) ES2054160T3 (en)
FI (1) FI92689C (en)
GR (1) GR3008294T3 (en)
HU (1) HU206308B (en)
PT (1) PT94318B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108863715B (en) * 2018-07-23 2021-07-20 蚌埠中实化学技术有限公司 Method for preparing dihydronopol by hydrogenation reduction of nopol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2097031A1 (en) * 1970-07-29 1972-03-03 Berri Balzac 2-aminoethoxyethyl-6,6-dimethyl nor pinane derivs - local anaesthetics spasmolytics and anticholinergics
JPS6049169B2 (en) * 1978-04-28 1985-10-31 花王株式会社 8-Exo-hydroxymethyl-endo-tricyclo[5.2.1.0↑2,↑6]decane ester and ether

Also Published As

Publication number Publication date
DK0406742T3 (en) 1993-05-17
EP0406742B1 (en) 1993-04-21
CA2020168C (en) 2000-05-02
FI92689B (en) 1994-09-15
PT94318B (en) 1997-02-28
FI92689C (en) 1994-12-27
PT94318A (en) 1991-03-20
DE59001237D1 (en) 1993-05-27
HU206308B (en) 1992-10-28
DD297956A5 (en) 1992-01-30
FI903439A0 (en) 1990-07-06
JP2807060B2 (en) 1998-09-30
JPH0344343A (en) 1991-02-26
HUT54340A (en) 1991-02-28
GR3008294T3 (en) 1993-09-30
ES2054160T3 (en) 1994-08-01
DE3922386A1 (en) 1991-01-17
ATE88456T1 (en) 1993-05-15
EP0406742A1 (en) 1991-01-09
HU904052D0 (en) 1990-12-28

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Legal Events

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