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CA2006184A1 - Prolonged release composition based on trimebutine and process for the preparation thereof - Google Patents

Prolonged release composition based on trimebutine and process for the preparation thereof

Info

Publication number
CA2006184A1
CA2006184A1 CA2006184A CA2006184A CA2006184A1 CA 2006184 A1 CA2006184 A1 CA 2006184A1 CA 2006184 A CA2006184 A CA 2006184A CA 2006184 A CA2006184 A CA 2006184A CA 2006184 A1 CA2006184 A1 CA 2006184A1
Authority
CA
Canada
Prior art keywords
trimebutine
preparation
composition based
release composition
prolonged release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2006184A
Other languages
French (fr)
Other versions
CA2006184C (en
Inventor
Loufty Omar Benkerrour
Francoise Chanoine
Jacques Sylvain Frances
Jean-Louis Junien
Gilbert Aubard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jouveinal SA
Original Assignee
Jouveinal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouveinal SA filed Critical Jouveinal SA
Publication of CA2006184A1 publication Critical patent/CA2006184A1/en
Application granted granted Critical
Publication of CA2006184C publication Critical patent/CA2006184C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Pharmaceutical composition in the form of a tablet comprising 2-dimethyl-amino-2-phenyl-1-butyl 3,4,5-trime-thoxybenzoate homogeneously dispersed in a hydrophilic porous matrix of hydroxypropylmethylcellulose as well as a water-souble diluent and tartaric acid.
CA002006184A 1988-12-28 1989-12-20 Prolonged release composition based on trimebutine and process for the preparation thereof Expired - Lifetime CA2006184C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8817303 1988-12-28
FR8817303A FR2640876B1 (en) 1988-12-28 1988-12-28

Publications (2)

Publication Number Publication Date
CA2006184A1 true CA2006184A1 (en) 1990-06-28
CA2006184C CA2006184C (en) 1999-11-23

Family

ID=9373520

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002006184A Expired - Lifetime CA2006184C (en) 1988-12-28 1989-12-20 Prolonged release composition based on trimebutine and process for the preparation thereof

Country Status (14)

Country Link
JP (1) JP2745232B2 (en)
KR (1) KR0137270B1 (en)
AT (1) AT397461B (en)
BE (1) BE1006002A4 (en)
CA (1) CA2006184C (en)
DE (1) DE3942131C2 (en)
EG (1) EG19994A (en)
ES (1) ES2019024A6 (en)
FR (1) FR2640876B1 (en)
GR (1) GR1000429B (en)
GT (1) GT198900080A (en)
IT (1) IT1236239B (en)
MX (1) MX170641B (en)
PT (1) PT92682B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255125A (en) * 1992-02-29 1993-10-05 Upjohn Co:The Sustained release preparation and its preparation
FR2730163B1 (en) * 1995-02-03 1997-04-04 Jouveinal Lab NOVEL PHARMACEUTICAL COMPOSITION CONTAINING TRIMEBUTINE AND PROCESS FOR THE PREPARATION THEREOF
FR2752162B1 (en) * 1996-08-07 1998-11-06 Jouveinal Lab TRIMEBUTINE FILM MALEATE TABLET
CN1927185B (en) * 2006-10-19 2010-05-19 开开援生制药股份有限公司 Maleic acid trimebutine slow release tablet comprising quick release part and preparing method thereof
KR101051630B1 (en) * 2008-10-02 2011-07-26 한국유나이티드제약 주식회사 Trimebutin sustained-release tablet with improved dissolution rate and ease of taking
FR2944971B1 (en) * 2009-04-30 2012-09-07 Roquette Freres COAGGLOMERATS OF MANNITOL AND GRANULAR STARCH TABLEABLE AND FREE-FLOW

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065143A (en) * 1960-04-19 1962-11-20 Richardson Merrell Inc Sustained release tablet
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
JPS5858146A (en) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd Microcapsule with fast releasability and preparation thereof
JPS5858145A (en) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd Microcapsule with fast releasability and preparation thereof
JPS5916821A (en) * 1982-07-16 1984-01-28 Tanabe Seiyaku Co Ltd Preparation of nonflocculating microcapsule
IT1206166B (en) * 1984-07-26 1989-04-14 Sigma Tau Ind Farmaceuti DEVICE FOR RELEASING A SUBSTANCE IN A DISSOLUTION FLUID WITH ZERO ORDER KINETICS AND PROCEDURE FOR ITS PREPARATION
GB8616669D0 (en) * 1986-07-09 1986-08-13 Merk Sharpe & Dohme Ltd Pharmaceutical compositions

Also Published As

Publication number Publication date
MX170641B (en) 1993-09-01
FR2640876B1 (en) 1993-09-24
KR0137270B1 (en) 1998-04-25
GR1000429B (en) 1992-07-30
PT92682A (en) 1990-06-29
DE3942131A1 (en) 1990-07-05
GT198900080A (en) 1991-06-20
IT1236239B (en) 1993-01-27
AT397461B (en) 1994-04-25
JPH02184624A (en) 1990-07-19
ATA294489A (en) 1993-09-15
CA2006184C (en) 1999-11-23
ES2019024A6 (en) 1991-05-16
BE1006002A4 (en) 1994-04-19
GR890100860A (en) 1991-03-15
JP2745232B2 (en) 1998-04-28
IT8912615A1 (en) 1991-06-20
KR900009060A (en) 1990-07-02
DE3942131C2 (en) 1998-09-17
PT92682B (en) 1997-01-31
IT8912615A0 (en) 1989-12-20
FR2640876A1 (en) 1990-06-29
EG19994A (en) 1997-01-30

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry