CA1273296C - Soluble collagen composition - Google Patents
Soluble collagen compositionInfo
- Publication number
- CA1273296C CA1273296C CA516291A CA516291A CA1273296C CA 1273296 C CA1273296 C CA 1273296C CA 516291 A CA516291 A CA 516291A CA 516291 A CA516291 A CA 516291A CA 1273296 C CA1273296 C CA 1273296C
- Authority
- CA
- Canada
- Prior art keywords
- collagen
- collagen sponge
- solution
- optically clear
- sponge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000008186 Collagen Human genes 0.000 title abstract 4
- 108010035532 Collagen Proteins 0.000 title abstract 4
- 229920001436 collagen Polymers 0.000 title abstract 4
- 239000000515 collagen sponge Substances 0.000 abstract 5
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000001913 cellulose Substances 0.000 abstract 2
- 230000036425 denaturation Effects 0.000 abstract 2
- 238000004925 denaturation Methods 0.000 abstract 2
- 238000001556 precipitation Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 230000000704 physical effect Effects 0.000 abstract 1
- 238000001226 reprecipitation Methods 0.000 abstract 1
Landscapes
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
Abstract
Abstract of the Disclosure SOLUBLE COLLAGEN SPONGE The invention concerns a collagen sponge which has a denaturation temperature of at least 37°C, is not cross-linked and in one of its two embodiments forms an optically clear solution in aqueous medium. As compared with the collagen sponges previously known, it is particularly suitable as support material for pharmaceutical and cosmetic active substances since it has a higher denaturation temperature than the latter and dissolves again in contact with body fluid. The collagen sponge of the invention is prepared from an optically clear collagen solution by precipitation with neutral salts, dissolving and reprecipitation and then subjecting the collagen to freeze-drying without removal of the precipitation salt. Acid-swollen collagens and/or cellulose or cellulose derivatives can also be added to the solution, whereby the physical properties of the collagen sponge can be affected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA516291A CA1273296C (en) | 1986-08-19 | 1986-08-19 | Soluble collagen composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA516291A CA1273296C (en) | 1986-08-19 | 1986-08-19 | Soluble collagen composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA1273296A CA1273296A (en) | 1990-08-28 |
| CA1273296C true CA1273296C (en) | 1990-08-28 |
Family
ID=4133757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA516291A Expired - Lifetime CA1273296C (en) | 1986-08-19 | 1986-08-19 | Soluble collagen composition |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA1273296C (en) |
-
1986
- 1986-08-19 CA CA516291A patent/CA1273296C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1273296A (en) | 1990-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed |