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CA1271281A - Biocompatible material for treatment of tissular or organic defects - Google Patents

Biocompatible material for treatment of tissular or organic defects

Info

Publication number
CA1271281A
CA1271281A CA000529120A CA529120A CA1271281A CA 1271281 A CA1271281 A CA 1271281A CA 000529120 A CA000529120 A CA 000529120A CA 529120 A CA529120 A CA 529120A CA 1271281 A CA1271281 A CA 1271281A
Authority
CA
Canada
Prior art keywords
cyanacrylate
alpha
biocompatible material
polyacrylic acid
linking agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000529120A
Other languages
French (fr)
Inventor
Anatoly B. Davydov
Valery N. Egiev
Anna I. Iliina
Jury P. Kapustin
Anesty K. Orfanidi
Alexei N. Smirnov
Eduard A. Stepanov
Valeria I. Timokhina
Anatoly N. Chigir
Kirill G. Schitkov
Alla Y. Akimova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena
VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSINSKOI TEKHNIKI
Original Assignee
Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena
VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSINSKOI TEKHNIKI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena, VSESOJUZNY NAUCHNO-ISSLEDOVATELSKY I ISPYTATELNY INSTITUT MEDITSINSKOI TEKHNIKI filed Critical Moskovsky Nauchno-Issledovatelsky Onkologichesky Institut Imeni Pa Gertsena
Priority to CA000529120A priority Critical patent/CA1271281A/en
Application granted granted Critical
Publication of CA1271281A publication Critical patent/CA1271281A/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ABSTRACT

A biocompatible material for treatment of tissular or organic defects is composed of a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular mass of 200,000 to 600,000, obtained by interaction of alpha-cyanacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows:
alpha-cyanacrylate 14 to 34 polyacrylic acid having a molecular mass of 200,000 to 600,000 15 to 43 cross-linking agent 71 to 23.

Claims (4)

The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows:
1. A biocompatible material for treatment of tissular or organic defects, comprising a graft copolymer of alpha-cyanacrylate and polyacrylic acid having a molecular mass of 200,000 to 600,000, obtained by interaction of alpha-cyanacrylate with polyacrylic acid in the presence of a cross-linking agent, the weight percentage ratio of the aforesaid components being as follows:
alpha-cyanacrylate 14 to 34 polyacrylic acid having a molecular mass of 200,000 to 600,000 15 to 43 cross linking agent 71 to 23
2. A biocompatible material as claimed in claim 1, which comprises, as an alpha-cyanacrylate, ethyl-alpha-cyanacrylate, ethoxyethyl alpha-cyanacrylate, butyl-alpha-cyanacrylate, or mixture thereof.
3. A biocompatible material as claimed in claim 1, which comprises, as a cross-linking agent, poly-vinyl alcohol having a molecular mass of 50,000 to 60,000, glycerol or a mixture of both.
4. A biocompatible material as claimed in claims 1, 2 or 3, which comprises additionally an antiseptic in an amount of 9 to 50 weight percent.
CA000529120A 1987-02-05 1987-02-05 Biocompatible material for treatment of tissular or organic defects Expired - Fee Related CA1271281A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA000529120A CA1271281A (en) 1987-02-05 1987-02-05 Biocompatible material for treatment of tissular or organic defects

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000529120A CA1271281A (en) 1987-02-05 1987-02-05 Biocompatible material for treatment of tissular or organic defects

Publications (1)

Publication Number Publication Date
CA1271281A true CA1271281A (en) 1990-07-03

Family

ID=4134915

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000529120A Expired - Fee Related CA1271281A (en) 1987-02-05 1987-02-05 Biocompatible material for treatment of tissular or organic defects

Country Status (1)

Country Link
CA (1) CA1271281A (en)

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