CA1271198C - 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs - Google Patents
5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogsInfo
- Publication number
- CA1271198C CA1271198C CA595286A CA595286A CA1271198C CA 1271198 C CA1271198 C CA 1271198C CA 595286 A CA595286 A CA 595286A CA 595286 A CA595286 A CA 595286A CA 1271198 C CA1271198 C CA 1271198C
- Authority
- CA
- Canada
- Prior art keywords
- epoxy
- prostaglandin analogs
- substituted prostaglandin
- oxabicycloheptane substituted
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
ABSTRACT A novel intermediate compound having the structure which is useful in the preparation of 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs having the structural formula wherein m is 1 to 5, R is H, lower alkyl, alkali metal or polyhydroxylamine, and R1 is lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl or lower alkenyl, which are themselves cardiovascular agents useful in the treatment of thrombotic disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000595286A CA1271198A (en) | 1985-05-21 | 1986-04-18 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US736,628 | 1985-05-21 | ||
| US06/736,628 US4611005A (en) | 1985-05-21 | 1985-05-21 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease |
| CA000595286A CA1271198A (en) | 1985-05-21 | 1986-04-18 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
| CA 507060 CA1270842C (en) | 1985-05-21 | 1986-04-18 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 507060 Division CA1270842C (en) | 1985-05-21 | 1986-04-18 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA1271198C true CA1271198C (en) | 1990-07-03 |
| CA1271198A CA1271198A (en) | 1990-07-03 |
Family
ID=25670964
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000595286A Expired - Lifetime CA1271198A (en) | 1985-05-21 | 1986-04-18 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
| CA000595287A Expired - Lifetime CA1270842A (en) | 1985-05-21 | 1989-03-30 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000595287A Expired - Lifetime CA1270842A (en) | 1985-05-21 | 1989-03-30 | 5,6-epoxy-7-oxabicycloheptane substituted prostaglandin analogs |
Country Status (1)
| Country | Link |
|---|---|
| CA (2) | CA1271198A (en) |
-
1986
- 1986-04-18 CA CA000595286A patent/CA1271198A/en not_active Expired - Lifetime
-
1989
- 1989-03-30 CA CA000595287A patent/CA1270842A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1270842A (en) | 1990-06-26 |
| CA1271198A (en) | 1990-07-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKLA | Lapsed | ||
| MKLA | Lapsed |
Effective date: 19930105 |