CA1265522C - - Google Patents
Info
- Publication number
- CA1265522C CA1265522C CA 448829 CA448829A CA1265522C CA 1265522 C CA1265522 C CA 1265522C CA 448829 CA448829 CA 448829 CA 448829 A CA448829 A CA 448829A CA 1265522 C CA1265522 C CA 1265522C
- Authority
- CA
- Canada
- Prior art keywords
- methyl
- yield obtained
- diastereomeric compounds
- derivative
- separated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA000576252A CA1265522A (en) | 1983-03-07 | 1988-08-31 | (+)-trans-3-¬(4-methoxyphenoxy)-methyl|-1- methyl-4-phenylperidine (+)-mandelate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK111583A DK149624C (da) | 1983-03-07 | 1983-03-07 | Fremgangsmaade til fremstilling af (+)-trans-3-((4-methoxyphenoxy)-methyl)-1-methyl-4-phenylpiperidin eller et farmaceutisk acceptabelt salt heraf ud fra en blanding af enantiomererne |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000576252A Division CA1265522A (en) | 1983-03-07 | 1988-08-31 | (+)-trans-3-¬(4-methoxyphenoxy)-methyl|-1- methyl-4-phenylperidine (+)-mandelate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA1257599A CA1257599A (en) | 1989-07-18 |
| CA1265522C true CA1265522C (xx) | 1990-02-06 |
Family
ID=8101175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000448829A Expired CA1257599A (en) | 1983-03-07 | 1984-03-05 | TRANS-3-[(4-METHOXYPHENOXY)-METHYL]-1-METHYL- 4-PHENYLPIPERIDINE |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4571424A (xx) |
| EP (1) | EP0123832B1 (xx) |
| JP (1) | JPS6069065A (xx) |
| AT (1) | ATE30910T1 (xx) |
| CA (1) | CA1257599A (xx) |
| DE (1) | DE3467574D1 (xx) |
| DK (1) | DK149624C (xx) |
| ES (1) | ES530355A0 (xx) |
| FI (1) | FI80261C (xx) |
| GR (1) | GR81929B (xx) |
| IE (1) | IE57002B1 (xx) |
| NO (1) | NO164594C (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| US5254556A (en) * | 1988-11-07 | 1993-10-19 | Janssen Pharmaceutica N.V. | 3-piperidinyl-1,2-benzisoxazoles |
| IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
| ATE155456T1 (de) * | 1993-05-28 | 1997-08-15 | Pfizer | Verfahren zur herstellung und optischen auflösung von 2-phenyl-3-aminopiperidine |
| US7470244B2 (en) * | 1996-01-26 | 2008-12-30 | Harrison Jr Shelton E | Flexion-discouraging splint system, method and device |
| KR100828218B1 (ko) | 2003-09-12 | 2008-05-07 | 화이자 인코포레이티드 | 알파-2-델타 리간드 및 세로토닌/노르아드레날린 재흡수 억제제를 포함하는 조합물 |
| DE102005063192A1 (de) * | 2005-12-30 | 2007-07-05 | Basf Ag | Racematspaltung von 2,6-trans-Dimethyl-morpholin |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| US4442113A (en) * | 1981-05-07 | 1984-04-10 | A/S Ferrosan | Long-term weight reduction of obese patients using femoxetine |
-
1983
- 1983-03-07 DK DK111583A patent/DK149624C/da not_active IP Right Cessation
-
1984
- 1984-02-29 US US06/584,721 patent/US4571424A/en not_active Expired - Lifetime
- 1984-03-01 IE IE496/84A patent/IE57002B1/en not_active IP Right Cessation
- 1984-03-05 CA CA000448829A patent/CA1257599A/en not_active Expired
- 1984-03-05 FI FI840872A patent/FI80261C/fi not_active IP Right Cessation
- 1984-03-06 NO NO840847A patent/NO164594C/no unknown
- 1984-03-07 ES ES530355A patent/ES530355A0/es active Granted
- 1984-03-07 AT AT84102439T patent/ATE30910T1/de not_active IP Right Cessation
- 1984-03-07 DE DE8484102439T patent/DE3467574D1/de not_active Expired
- 1984-03-07 JP JP59042208A patent/JPS6069065A/ja active Pending
- 1984-03-07 GR GR74014A patent/GR81929B/el unknown
- 1984-03-07 EP EP84102439A patent/EP0123832B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK149624C (da) | 1987-02-02 |
| GR81929B (xx) | 1984-12-12 |
| EP0123832A1 (en) | 1984-11-07 |
| US4571424A (en) | 1986-02-18 |
| JPS6069065A (ja) | 1985-04-19 |
| FI80261B (fi) | 1990-01-31 |
| ATE30910T1 (de) | 1987-12-15 |
| CA1257599A (en) | 1989-07-18 |
| DE3467574D1 (en) | 1987-12-23 |
| IE57002B1 (en) | 1992-03-11 |
| DK149624B (da) | 1986-08-18 |
| EP0123832B1 (en) | 1987-11-19 |
| FI840872A0 (fi) | 1984-03-05 |
| NO840847L (no) | 1984-09-10 |
| ES8504710A1 (es) | 1985-05-01 |
| NO164594C (no) | 1990-10-24 |
| NO164594B (no) | 1990-07-16 |
| ES530355A0 (es) | 1985-05-01 |
| FI80261C (fi) | 1990-05-10 |
| DK111583D0 (da) | 1983-03-07 |
| DK111583A (da) | 1984-09-08 |
| IE840496L (en) | 1984-09-07 |
| FI840872A (fi) | 1984-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |