CA1217156A - Proteines hybrides - Google Patents

Proteines hybrides

Info

Publication number: CA1217156A
Authority: CA; Canada
Prior art keywords: fragment; hybrid protein; diphtheria toxin; cells; gene
Prior art date: 1982-05-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

CA000427998A

Other languages

English (en)

Inventor

John R. Murphy

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Harvard University

Original Assignee

Harvard University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-12

Filing date

1983-05-12

Publication date

1987-01-27

1983-05-12 Application filed by Harvard University filed Critical Harvard University

1987-01-27 Application granted granted Critical

1987-01-27 Publication of CA1217156A publication Critical patent/CA1217156A/fr

Status Expired legal-status Critical Current

Links

108090000623 proteins and genes Proteins 0.000 title claims abstract description 156
102000004169 proteins and genes Human genes 0.000 title claims abstract description 84
239000012634 fragment Substances 0.000 claims abstract description 187
239000003446 ligand Substances 0.000 claims abstract description 58
108010053187 Diphtheria Toxin Proteins 0.000 claims abstract description 42
102000016607 Diphtheria Toxin Human genes 0.000 claims abstract description 39
108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 38
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108010079345 Follicle Stimulating Hormone Proteins 0.000 description 1
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102000009151 Luteinizing Hormone Human genes 0.000 description 1
108010073521 Luteinizing Hormone Proteins 0.000 description 1
BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 1
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101150017997 Tox gene Proteins 0.000 description 1
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102000002852 Vasopressins Human genes 0.000 description 1
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KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 description 1
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Landscapes

Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)

CA000427998A 1982-05-12 1983-05-12 Proteines hybrides Expired CA1217156A (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US37738682A	1982-05-12	1982-05-12
US377,386		1982-05-12
US49377583A	1983-05-12	1983-05-12
US493,775		1983-05-12

Publications (1)

Publication Number	Publication Date
CA1217156A true CA1217156A (fr)	1987-01-27

Family

ID=27007799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA000427998A Expired CA1217156A (fr)	1982-05-12	1983-05-12	Proteines hybrides

Country Status (1)

Country	Link
CA (1)	CA1217156A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196320A (en) *	1989-09-20	1993-03-23	Abbott Biotech, Inc.	Method of producing engineered binding proteins

1983
- 1983-05-12 CA CA000427998A patent/CA1217156A/fr not_active Expired

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5196320A (en) *	1989-09-20	1993-03-23	Abbott Biotech, Inc.	Method of producing engineered binding proteins
US5338669A (en) *	1989-09-20	1994-08-16	Abbott Biotech, Incorporated	Method of producing fusion proteins

Publication	Publication Date	Title
EP0108146B1 (fr)	1987-01-28	Gènes de fusion codant des protéines hybrides, vecteurs de clonage les contenant et leur emploi
US5080898A (en)	1992-01-14	Enzymatically active toxin coupled to a cell-specific ligand
US6022950A (en)	2000-02-08	Hybrid molecules having translocation region and cell-binding region
US5965406A (en)	1999-10-12	Recombinant DNAS encoding three-part hybrid proteins
AU657087B2 (en)	1995-03-02	Hybrid molecules having translocation region and cell-binding region
EP0246307B1 (fr)	1994-02-02	Adn modifie par un codon cys
EP0185076B1 (fr)	1992-08-05	Proteine hybride
EP0369566A2 (fr)	1990-05-23	Anticorps chimériques bifonctionnels
JPH07508641A (ja)	1995-09-28	高められた活性を有する組換シュードモナス外毒素
US5932471A (en)	1999-08-03	DNA encoding chimeric toxin
EP0150572A1 (fr)	1985-08-07	Expression microbienne de facteur à croissance de type I, polypeptides analogiques et polypeptides hybridisés de EGF/TGF
EP0402544B1 (fr)	1995-05-03	Séquence nucléotide codant pour une protéine végétale inactivant le ribosomes
CA1217156A (fr)	1987-01-27	Proteines hybrides
EP0811683B1 (fr)	2008-01-23	Anticorps contre le précurseur humain de la peptide libérant la gastrine et son utilisation
US5529932A (en)	1996-06-25	Isolated DNA encoding a plant ribosome inactivating protein from the leaves of saponaria officinalis
JPS61501168A (ja)	1986-06-12	生長因子における改良

Legal Events

Date	Code	Title	Description
2004-01-27	MKEX	Expiry