CA1209433A - Non-metallic, bio-compatible hemostatic clips (two piece clip configured to lock tighter the larger the vessel being closed) - Google Patents
Non-metallic, bio-compatible hemostatic clips (two piece clip configured to lock tighter the larger the vessel being closed)Info
- Publication number
- CA1209433A CA1209433A CA000437364A CA437364A CA1209433A CA 1209433 A CA1209433 A CA 1209433A CA 000437364 A CA000437364 A CA 000437364A CA 437364 A CA437364 A CA 437364A CA 1209433 A CA1209433 A CA 1209433A
- Authority
- CA
- Canada
- Prior art keywords
- vessel
- piece
- clip
- legs
- closed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000002439 hemostatic effect Effects 0.000 title claims abstract description 21
- 210000005069 ears Anatomy 0.000 claims description 5
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 5
- 210000004204 blood vessel Anatomy 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 238000007373 indentation Methods 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 244000228957 Ferula foetida Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 229940030225 antihemorrhagics Drugs 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 1
- 238000002406 microsurgery Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920000117 poly(dioxanone) Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/122—Clamps or clips, e.g. for the umbilical cord
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Materials For Medical Uses (AREA)
Abstract
NON-METALLIC, BIO-COMPATIBLE HEMOSTATIC CLIPS (TWO PIECE
CLIP CONFIGURED TO LOCK TIGHTER THE LARGER THE VESSEL
BEING CLOSED) Abstract A sterile, two-piece hemostatic clip for occluding vessels. The first piece has a vessel clamping surface and a pair of legs extending from that surface. The second piece has a vessel clamping surface and locks with the first piece so that the vessel clamping surfaces face each other. The clamping surfaces are configured such that the locking forces are increased the greater the stress placed on the vessel clamping surfaces.
CLIP CONFIGURED TO LOCK TIGHTER THE LARGER THE VESSEL
BEING CLOSED) Abstract A sterile, two-piece hemostatic clip for occluding vessels. The first piece has a vessel clamping surface and a pair of legs extending from that surface. The second piece has a vessel clamping surface and locks with the first piece so that the vessel clamping surfaces face each other. The clamping surfaces are configured such that the locking forces are increased the greater the stress placed on the vessel clamping surfaces.
Description
NON-METALLIC, BIO-COMPATIBLE ~EMOSTATIC CLIPS (TWO PIECE
CLIP CONFIGURED TO LOCK TIGHTER THE LARGER THE VESSEL
BEING CLOSED) The present invention relates to hemostatic clips and more particularly to hemostatic clips fabricated from bio-compatible polymeric material which may be absorbable or non-absorbable in body tissue.
Background of the Invention In many surgical procedures, it is often necessary to ligate a plurality of vessels within the surgical site.
The vessels may be severed downstream of the ligated portion. In some instances, a vessel may be ligated in spaced apart areas and the portion of the vessel between the ligations removed. The purpose of ligating vessels is to maintain the surgical site free from an excess of blood and reduce blood loss in the patient. Also in some ~0 surgical procedures where tumors and the like are to be removed, the tumor or organ may have to be separated from said vessels. Before separating, the vessels are ligated.
Once a blood vessel is completely shut off, hemostatis, that is, the natur-al closing of the end of the vessel so as to stop blood flow, will occur within several days time depending on the vessel. The body in the meantime will continue to allow blood flow around the ligated area through appropriate capillaries and secondary vessels with the natural psysiological function of the body enlarging these bypass vessels until adequate blood flow is obtained. Hence, when ligating the vessel there should be ~ositive stoppage of the blood flow in the main vessel.
Failure to provide complete stoppage may cause blood loss in the patient and may also disrupt the natural hemostatis and concurrent manufacture of new paths of blood flow in the patient. ~r~
E~.~543 ~ZU9433 In the past, the closing of the vessel was usually accomplished using ligatures; that is, filaments or threads which the doctor tied around the vessel to be closed. This is a time-consuming process and one where positive closure of the vessel is not always accomplished.
In recent years hemostatic clips have been replaced by ligatures in surgical procedures to close biood vessels and other ovaducts. Very often these hemostatic clips are narrow U or V shaped strips formed of tantalum or stainless steel which are capable of being deformed and possess sufficient strength to retain the deformation while clamped about a blood vessel. Even more recently, ( hemostatic clips made from biocompatible polymer materials which are either absorbable or non-absorbable in body tissue have been used to ligate vessels. ~xamples of such polymeric hemostatic clips are disclosed in copending commonly assigned Canadian pa~ent Nos 1,157,335; 1,162,454;
and 1,157,334.
In most instances, the hemostatic clip should positively close the vessel and stop the flow of blood. The clip should be sufficiently tight about the vessel so that when the surgeon is working in the cavity or area where the vessels have been ligated, the surgeon will not inadvertently remove or disrupt a hemostatic clip either with a sponge or movement of an instrument or the like.
The clip should have simple~ smooth lines to reduce possible trauma and make the clip relatively easy to manufacture.
What we have discovered is an improved ligating clip structure which, when placed about a vessell closes the vessel and positively locks the vessel closed. Our new improved hemostatic clip locks tighter to the vessel the larger the vessel and the more pressure placed on the clip by the blood trying to flow through the vessel. our clip lZ09433 once locked in place is not inadvertently removed or unlocked by being jostled. Our new improved hemostatic clip has simple, smooth lines and is easy to manufacture.
Summary of the Present Invention A sterile, two-piece, hemostatic clip for occluding vessels. The clip comprises a first piece having a horizontal or spanning member with a vessel clamping surface. A leg member is disposed from each end of the horizontal member from the same side of the member as the vessel clamping surface and substantially perpendicular thereto. The first piece is adapted to be placed on the vessel to be occluded by placing the leg members on opposite sides of the vessel and the vessel clamping surface in contact with the vessel. The clip includes a second piece having a vessel clamping surface. The second piece is adapted to connect the leg members of the first piece and interlock therewith with the vessel clamping surface in contact with the vessel being occluded. The leg members of the first piece and the second piece combine to render the interlock more secure the greater the stress placed against the vessel clamping surfaces.
In certain embodiments of the present invention, the horizontal member of the first piece has a smaller cross-sectional area than the cross~sectional area of the second piece so that the greater the pressure placed on the vessel clamping surfaces of the clip the more the horizontal member is deflected and the more the leg members are urged towards one another and the tighter the two pieces of the clip are held together.
~ ~
. .'~
1209~3 According to a still further broad aspect of the pre-sent invention, there is provided a sterile, two~piece hemostatic clip for occluding vessels. The clip com-prises a first piece having a spanning member with a vessel clamping surface. A leg member is disposed at each end of the spanning member from the same side as the vessel clamping surface. Each of the leg members comprises a U-shaped member with the inner facing sur-faces of the legs of the U being beveled from their free ends towards the base of the U. The beveled sur-faces terminate above the base of the U to form locking ears. The first piece is adapted to be placed on the vessel to be occluded by placing the associated U-shaped legs on opposite sides of the vessel and the vessel clamping inner surface in contact with the vessel and a straight second piece having a vessel clamping surface. The second piece is sized and con-figured to extend between the fit within each of the U-shaped members and adapted to fit between the legs of the U and be held in place by the ears.
Brief Description of the Drawings The present invention will be more fully described in conjunction with the accompaying drawings wherein;
1~094~3 !-Figure 1 is an enlarged perspective view of the new two-piece clip of the present invention with the pieces positioned in spaced apart relationship;
Figure 2 is an enlarged perspective view of the clip of Figure 1 closed about a blood vessel;
Figure 3 is an enlarged perspective view of another embodiment of the clip of the present invention closed about the blood vessel;
Figure 4 is a side view showing an instrument for applying the clips of the present invention; and , .
Figure 5 is an enlarged perspective view showing the jaws of an instrument used for applying the clips of the present invention.
Detailed Description of the Invention Referring to the drawings, in Figure 1 there is shown a clip 10 of the present invention. The clip comprises two separate pieces. The first piece 11 has a horizontal or spanning member 12. One surface of the member forms a vessel clamping surface 13. Disposed at opposite ends of the spanning member from the vessel clamping surface are legs 14 and 15. The second piece 1~ is a straight member having a vessel clamping surface 17 and has disposed at opposite ends indentations 13 and 19. The indentations are sized to accept the legs. As may be seen-, the legs are bulged 20 and 21 outwardly from the surfaces of the legs facing each other adjacent the free end 22 and 23 of each leg. As more clearly shown in Figure 2, in use, the first piece is placed over the vessel 24 to be occluded or closed and the second piece placed between the legs and forced over the bulges in the legs to occlude the vessel.
12(~94~3 As may be seen in Figure 1, the cross-sectional area of the horizontal member of the first piece is smaller than the cross-sectional area of the second piece. In use, the larger the vessel or the greater the pressure of the blood flowing through the vessel the more the horizontal member of the first piece is deformed outwardly (the direction of the arrow) and the legs of the first piece urged toward each other and the tighter the clip is held in the closed position.
In Figure 3, there is shown another embodiment of the new two-piece hemostatic clip 28 of the present invention. In this embodiment, the first piece 29 comprises a horizontal member 30 with two U-shaped leg members 31 and 32 extending from opposite ends of the vessel clamping surface 33 of the horizontal or spanning member. Each leg of the U-shaped members has a beveled inner surface 34 extending from the free end of the leg towards the base of the U and terminating at an ear 35. The second piece 36 comprises a straight member having a rounded vessel clamping surface 37 and a flat locking surface 3~. The vessel clamping surface of the first piece is placed on the vessel to be occluded. The second piece is pressed - between-the legs of the U. -The legs are deflected outwardly until the flat surface of the piece passes by the ears and is locked in place. When in the locked position, the larger the vessel or the greater the pressure in the vessel, the more force is applied against the vessel clamping surfaces of the first piece and second piece and the tighter the two pieces are interlocked.
Figure 4 illustrates a forceps type ligating clip applier 45. The applier comprises two handle members 46 and 47 crossing at a hinge point 48 and maintained in a normally open position by a spring 4~. One handle extends beyond the hinge forming jaw member 50 while the extension of the ~Z~9'~3 other handle extends beyond the hing~ to form a corresponding jaw member 51. As more clearly shown in the enlarged view in Figure 5, the jaws 50 and 51 are constructed to accept the two pieces 52 and 53 of the clip. The first piece 52 comprises a horizontal member with two leg members and held in the jaw by frictional engagement between the inner side surfaces of the jaw and the side surfaces of the piece. The opposite jaw 51 holds the other piece 53 in place in a similar manner utilizing friction. Openings 56 and 57 are disposed in the jaw 52 adjacent opposite ends of the piece. These openings allow - the legs of the first piece to be inserted past the second piece to lock the clip in place about the vessel to occlude the vessel. Once the clip is locked about the vessel, the frictional forces arë not sufficient to maintain the piece in the jaws of the clip and the instrument may be readily rernoved and the clip allowed to remain about the vessel.
The clips of the present invention may be constructed in various sizes according to their intended function. Hemo-static clips are usually less than 6 millimeters in length and 1 1/2 millimeters in length. The dimension of the - clip may be reduced by about 50% for certain applications in microsurgery. Larger clips for special hemostatic applications may be about double the size of a typical hemostatic clip. The various sizes of the clip are preferably matched with individual appliers having jaws tailored to the size of the clip for best performance.
The clips of the present invention are most conveniently molded of biologically acceptable polyr~leric materials which may be absorbable or non-absorbable in body tissue.
Preferred absorbable polymers or copolymers incl~de those of glycolide, lactide and poly(p)dioxanone Preferred non-absorbable polymers include nylon, polyesters, and ETI~-543 ~'2~)9433 polypropylene. All these materials have been demonstrated to be biologically acceptable when used as sutures or other implantable medical devices.
The clips are sterilized by any of the well known sterili-zation techniques and the technique selected will depend to a great extent on the material used to make the clip.
Suitable sterilization techniques include heat or steam sterilization, radiation sterilization such as cobalt irradiation, electron beam and the like, ethylene oxide, and other sterilization techniques well known in the art. --The clips of the present invention may be easily and economically manufactured by injection molding or other suitable molding techniques well known in the art.
Having now described the present invention and certain specific embodiments thereof, it will be readily apparent to those skilled in the art that many variations and modifications mav be made to the present invention without departing from the spirit and scope thereof.
ETi;-543
CLIP CONFIGURED TO LOCK TIGHTER THE LARGER THE VESSEL
BEING CLOSED) The present invention relates to hemostatic clips and more particularly to hemostatic clips fabricated from bio-compatible polymeric material which may be absorbable or non-absorbable in body tissue.
Background of the Invention In many surgical procedures, it is often necessary to ligate a plurality of vessels within the surgical site.
The vessels may be severed downstream of the ligated portion. In some instances, a vessel may be ligated in spaced apart areas and the portion of the vessel between the ligations removed. The purpose of ligating vessels is to maintain the surgical site free from an excess of blood and reduce blood loss in the patient. Also in some ~0 surgical procedures where tumors and the like are to be removed, the tumor or organ may have to be separated from said vessels. Before separating, the vessels are ligated.
Once a blood vessel is completely shut off, hemostatis, that is, the natur-al closing of the end of the vessel so as to stop blood flow, will occur within several days time depending on the vessel. The body in the meantime will continue to allow blood flow around the ligated area through appropriate capillaries and secondary vessels with the natural psysiological function of the body enlarging these bypass vessels until adequate blood flow is obtained. Hence, when ligating the vessel there should be ~ositive stoppage of the blood flow in the main vessel.
Failure to provide complete stoppage may cause blood loss in the patient and may also disrupt the natural hemostatis and concurrent manufacture of new paths of blood flow in the patient. ~r~
E~.~543 ~ZU9433 In the past, the closing of the vessel was usually accomplished using ligatures; that is, filaments or threads which the doctor tied around the vessel to be closed. This is a time-consuming process and one where positive closure of the vessel is not always accomplished.
In recent years hemostatic clips have been replaced by ligatures in surgical procedures to close biood vessels and other ovaducts. Very often these hemostatic clips are narrow U or V shaped strips formed of tantalum or stainless steel which are capable of being deformed and possess sufficient strength to retain the deformation while clamped about a blood vessel. Even more recently, ( hemostatic clips made from biocompatible polymer materials which are either absorbable or non-absorbable in body tissue have been used to ligate vessels. ~xamples of such polymeric hemostatic clips are disclosed in copending commonly assigned Canadian pa~ent Nos 1,157,335; 1,162,454;
and 1,157,334.
In most instances, the hemostatic clip should positively close the vessel and stop the flow of blood. The clip should be sufficiently tight about the vessel so that when the surgeon is working in the cavity or area where the vessels have been ligated, the surgeon will not inadvertently remove or disrupt a hemostatic clip either with a sponge or movement of an instrument or the like.
The clip should have simple~ smooth lines to reduce possible trauma and make the clip relatively easy to manufacture.
What we have discovered is an improved ligating clip structure which, when placed about a vessell closes the vessel and positively locks the vessel closed. Our new improved hemostatic clip locks tighter to the vessel the larger the vessel and the more pressure placed on the clip by the blood trying to flow through the vessel. our clip lZ09433 once locked in place is not inadvertently removed or unlocked by being jostled. Our new improved hemostatic clip has simple, smooth lines and is easy to manufacture.
Summary of the Present Invention A sterile, two-piece, hemostatic clip for occluding vessels. The clip comprises a first piece having a horizontal or spanning member with a vessel clamping surface. A leg member is disposed from each end of the horizontal member from the same side of the member as the vessel clamping surface and substantially perpendicular thereto. The first piece is adapted to be placed on the vessel to be occluded by placing the leg members on opposite sides of the vessel and the vessel clamping surface in contact with the vessel. The clip includes a second piece having a vessel clamping surface. The second piece is adapted to connect the leg members of the first piece and interlock therewith with the vessel clamping surface in contact with the vessel being occluded. The leg members of the first piece and the second piece combine to render the interlock more secure the greater the stress placed against the vessel clamping surfaces.
In certain embodiments of the present invention, the horizontal member of the first piece has a smaller cross-sectional area than the cross~sectional area of the second piece so that the greater the pressure placed on the vessel clamping surfaces of the clip the more the horizontal member is deflected and the more the leg members are urged towards one another and the tighter the two pieces of the clip are held together.
~ ~
. .'~
1209~3 According to a still further broad aspect of the pre-sent invention, there is provided a sterile, two~piece hemostatic clip for occluding vessels. The clip com-prises a first piece having a spanning member with a vessel clamping surface. A leg member is disposed at each end of the spanning member from the same side as the vessel clamping surface. Each of the leg members comprises a U-shaped member with the inner facing sur-faces of the legs of the U being beveled from their free ends towards the base of the U. The beveled sur-faces terminate above the base of the U to form locking ears. The first piece is adapted to be placed on the vessel to be occluded by placing the associated U-shaped legs on opposite sides of the vessel and the vessel clamping inner surface in contact with the vessel and a straight second piece having a vessel clamping surface. The second piece is sized and con-figured to extend between the fit within each of the U-shaped members and adapted to fit between the legs of the U and be held in place by the ears.
Brief Description of the Drawings The present invention will be more fully described in conjunction with the accompaying drawings wherein;
1~094~3 !-Figure 1 is an enlarged perspective view of the new two-piece clip of the present invention with the pieces positioned in spaced apart relationship;
Figure 2 is an enlarged perspective view of the clip of Figure 1 closed about a blood vessel;
Figure 3 is an enlarged perspective view of another embodiment of the clip of the present invention closed about the blood vessel;
Figure 4 is a side view showing an instrument for applying the clips of the present invention; and , .
Figure 5 is an enlarged perspective view showing the jaws of an instrument used for applying the clips of the present invention.
Detailed Description of the Invention Referring to the drawings, in Figure 1 there is shown a clip 10 of the present invention. The clip comprises two separate pieces. The first piece 11 has a horizontal or spanning member 12. One surface of the member forms a vessel clamping surface 13. Disposed at opposite ends of the spanning member from the vessel clamping surface are legs 14 and 15. The second piece 1~ is a straight member having a vessel clamping surface 17 and has disposed at opposite ends indentations 13 and 19. The indentations are sized to accept the legs. As may be seen-, the legs are bulged 20 and 21 outwardly from the surfaces of the legs facing each other adjacent the free end 22 and 23 of each leg. As more clearly shown in Figure 2, in use, the first piece is placed over the vessel 24 to be occluded or closed and the second piece placed between the legs and forced over the bulges in the legs to occlude the vessel.
12(~94~3 As may be seen in Figure 1, the cross-sectional area of the horizontal member of the first piece is smaller than the cross-sectional area of the second piece. In use, the larger the vessel or the greater the pressure of the blood flowing through the vessel the more the horizontal member of the first piece is deformed outwardly (the direction of the arrow) and the legs of the first piece urged toward each other and the tighter the clip is held in the closed position.
In Figure 3, there is shown another embodiment of the new two-piece hemostatic clip 28 of the present invention. In this embodiment, the first piece 29 comprises a horizontal member 30 with two U-shaped leg members 31 and 32 extending from opposite ends of the vessel clamping surface 33 of the horizontal or spanning member. Each leg of the U-shaped members has a beveled inner surface 34 extending from the free end of the leg towards the base of the U and terminating at an ear 35. The second piece 36 comprises a straight member having a rounded vessel clamping surface 37 and a flat locking surface 3~. The vessel clamping surface of the first piece is placed on the vessel to be occluded. The second piece is pressed - between-the legs of the U. -The legs are deflected outwardly until the flat surface of the piece passes by the ears and is locked in place. When in the locked position, the larger the vessel or the greater the pressure in the vessel, the more force is applied against the vessel clamping surfaces of the first piece and second piece and the tighter the two pieces are interlocked.
Figure 4 illustrates a forceps type ligating clip applier 45. The applier comprises two handle members 46 and 47 crossing at a hinge point 48 and maintained in a normally open position by a spring 4~. One handle extends beyond the hinge forming jaw member 50 while the extension of the ~Z~9'~3 other handle extends beyond the hing~ to form a corresponding jaw member 51. As more clearly shown in the enlarged view in Figure 5, the jaws 50 and 51 are constructed to accept the two pieces 52 and 53 of the clip. The first piece 52 comprises a horizontal member with two leg members and held in the jaw by frictional engagement between the inner side surfaces of the jaw and the side surfaces of the piece. The opposite jaw 51 holds the other piece 53 in place in a similar manner utilizing friction. Openings 56 and 57 are disposed in the jaw 52 adjacent opposite ends of the piece. These openings allow - the legs of the first piece to be inserted past the second piece to lock the clip in place about the vessel to occlude the vessel. Once the clip is locked about the vessel, the frictional forces arë not sufficient to maintain the piece in the jaws of the clip and the instrument may be readily rernoved and the clip allowed to remain about the vessel.
The clips of the present invention may be constructed in various sizes according to their intended function. Hemo-static clips are usually less than 6 millimeters in length and 1 1/2 millimeters in length. The dimension of the - clip may be reduced by about 50% for certain applications in microsurgery. Larger clips for special hemostatic applications may be about double the size of a typical hemostatic clip. The various sizes of the clip are preferably matched with individual appliers having jaws tailored to the size of the clip for best performance.
The clips of the present invention are most conveniently molded of biologically acceptable polyr~leric materials which may be absorbable or non-absorbable in body tissue.
Preferred absorbable polymers or copolymers incl~de those of glycolide, lactide and poly(p)dioxanone Preferred non-absorbable polymers include nylon, polyesters, and ETI~-543 ~'2~)9433 polypropylene. All these materials have been demonstrated to be biologically acceptable when used as sutures or other implantable medical devices.
The clips are sterilized by any of the well known sterili-zation techniques and the technique selected will depend to a great extent on the material used to make the clip.
Suitable sterilization techniques include heat or steam sterilization, radiation sterilization such as cobalt irradiation, electron beam and the like, ethylene oxide, and other sterilization techniques well known in the art. --The clips of the present invention may be easily and economically manufactured by injection molding or other suitable molding techniques well known in the art.
Having now described the present invention and certain specific embodiments thereof, it will be readily apparent to those skilled in the art that many variations and modifications mav be made to the present invention without departing from the spirit and scope thereof.
ETi;-543
Claims (2)
1. A sterile, two-piece hemostatic clip for occluding vessels, said clip comprising a first piece having a spanning member with a vessel clamping sur-face, a leg member disposed at each end of said span-ning member from the same side as said vessel clamping surface, each of said leg members comprising a U-shaped member with the inner facing surfaces of the legs of the U being beveled from their free ends towards the base of the U, said beveled surfaces terminating above the base of the U to form locking ears, said first piece being adapted to be placed on the vessel to be occluded by placing the associated U-shaped legs on opposite sides of the vessel and the vessel clamping inner surface in contact with said vessel and a straight second piece having a vessel clamping surface, said second piece being sized and configured to extend between the fit within each of said U-shaped members and adapted to fit between the legs of the U and be held in place by said ears.
2. A sterile, two-piece hemostatic clip according to claim 1 wherein the vessel clamping sur-face of the second piece is rounded.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42298182A | 1982-09-24 | 1982-09-24 | |
| US422,981 | 1982-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1209433A true CA1209433A (en) | 1986-08-12 |
Family
ID=23677196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000437364A Expired CA1209433A (en) | 1982-09-24 | 1983-09-22 | Non-metallic, bio-compatible hemostatic clips (two piece clip configured to lock tighter the larger the vessel being closed) |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5982843A (en) |
| CA (1) | CA1209433A (en) |
| DE (1) | DE3334502A1 (en) |
| GB (1) | GB2127481A (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3421567A1 (en) * | 1984-06-09 | 1985-12-12 | Kaco Gmbh + Co, 7100 Heilbronn | Clamping device |
| DE3445874C1 (en) * | 1984-12-15 | 1986-08-14 | Aesculap-Werke Ag Vormals Jetter & Scheerer, 7200 Tuttlingen | Clip for closing egg or spermatic ducts |
| US5282811A (en) * | 1992-04-16 | 1994-02-01 | Cook Pacemaker Corporation | Two part surgical ligating clip, applicator and method of use |
| CN114767947B (en) * | 2022-05-05 | 2023-02-14 | 暨南大学 | Absorbable vascular clamp made of polyester composite material and preparation method of absorbable vascular clamp |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3147754A (en) * | 1961-04-17 | 1964-09-08 | Walter R Koessler | Device for controlling incontinence |
| GB972731A (en) * | 1961-05-31 | 1964-10-14 | Mihaly Gerendas | Improvements in or relating to artery clamps |
| GB1020035A (en) * | 1962-11-02 | 1966-02-16 | Nils Lage Wilhelm Posse | Improvements in or relating to clamps |
| GB1147940A (en) * | 1966-11-29 | 1969-04-10 | Dom Holdings Ltd | Improvements in or relating to clips |
| GB1208437A (en) * | 1967-11-10 | 1970-10-14 | Furse W J & Co Ltd | Clip e.g. for use in lightning protection systems |
| GB1242632A (en) * | 1969-01-16 | 1971-08-11 | Celmac Plasclip Ltd | Improvements in or relating to distance pieces for concrete re-inforcing rods |
| US3760811A (en) * | 1970-01-20 | 1973-09-25 | D Andrew | Endotracheal tube clamp |
| GB1500698A (en) * | 1975-02-11 | 1978-02-08 | Hawker Siddeley Aviation Ltd | Clamps for flat cables |
| US4060089A (en) * | 1975-09-03 | 1977-11-29 | United States Surgical Corporation | Surgical fastening method and device therefor |
| IN151996B (en) * | 1979-06-18 | 1983-09-17 | Ethicon Inc | |
| DE2932652A1 (en) * | 1979-08-11 | 1981-02-26 | Bleier Waldemar | Human organ passage two=part clip - has jaws with rigid clamping faces secured together by end hooks |
| MX151148A (en) * | 1980-02-25 | 1984-10-04 | Johnson & Johnson | IMPROVEMENTS IN HEMOSTATIC FORCEPS |
| US4646741A (en) * | 1984-11-09 | 1987-03-03 | Ethicon, Inc. | Surgical fastener made from polymeric blends |
-
1983
- 1983-09-21 JP JP58173300A patent/JPS5982843A/en active Granted
- 1983-09-22 CA CA000437364A patent/CA1209433A/en not_active Expired
- 1983-09-23 GB GB08325588A patent/GB2127481A/en not_active Withdrawn
- 1983-09-23 DE DE19833334502 patent/DE3334502A1/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GB8325588D0 (en) | 1983-10-26 |
| JPH0336535B2 (en) | 1991-05-31 |
| JPS5982843A (en) | 1984-05-14 |
| DE3334502C2 (en) | 1992-11-26 |
| DE3334502A1 (en) | 1984-03-29 |
| GB2127481A (en) | 1984-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |