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CA1163631A - Isoxazole derivatives and a process for the preparation thereof - Google Patents

Isoxazole derivatives and a process for the preparation thereof

Info

Publication number
CA1163631A
CA1163631A CA000373380A CA373380A CA1163631A CA 1163631 A CA1163631 A CA 1163631A CA 000373380 A CA000373380 A CA 000373380A CA 373380 A CA373380 A CA 373380A CA 1163631 A CA1163631 A CA 1163631A
Authority
CA
Canada
Prior art keywords
general formula
compound
group
methyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000373380A
Other languages
English (en)
French (fr)
Inventor
Rezso Bognar
Jozsef Szegi
Ferenc Sztaricskai
Istvan P. Ferenczik
Zoltan Gyorgydeak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Application granted granted Critical
Publication of CA1163631A publication Critical patent/CA1163631A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA000373380A 1980-03-19 1981-03-19 Isoxazole derivatives and a process for the preparation thereof Expired CA1163631A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU8080637A HU180567B (en) 1980-03-19 1980-03-19 Method for producing derivatives of isooxazole
HU637/80 1980-03-19

Publications (1)

Publication Number Publication Date
CA1163631A true CA1163631A (en) 1984-03-13

Family

ID=10950573

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000373380A Expired CA1163631A (en) 1980-03-19 1981-03-19 Isoxazole derivatives and a process for the preparation thereof

Country Status (15)

Country Link
JP (1) JPS56158774A (sv)
BE (1) BE887954A (sv)
CA (1) CA1163631A (sv)
CH (1) CH646157A5 (sv)
DE (1) DE3110817A1 (sv)
DK (3) DK151012C (sv)
ES (3) ES501095A0 (sv)
FI (1) FI70011C (sv)
FR (1) FR2478634A1 (sv)
GB (1) GB2075009B (sv)
HU (1) HU180567B (sv)
IT (1) IT1211010B (sv)
SE (1) SE454695B (sv)
SU (3) SU1053750A3 (sv)
YU (1) YU42560B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1138764C (zh) * 1997-04-21 2004-02-18 住友制药株式会社 异噁唑衍生物
US6100260A (en) * 1997-04-21 2000-08-08 Sumitomo Pharmaceutical Company, Limited Isoxazole derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL302496A (sv) * 1962-12-22
US3808221A (en) * 1971-04-14 1974-04-30 Hoffmann La Roche Antiandrogenic n-(3,5-dilower alkyl-4-heterocyclic)methyl)phthalimides

Also Published As

Publication number Publication date
DK23087A (da) 1987-01-16
SU1053750A3 (ru) 1983-11-07
SE8101703L (sv) 1981-09-20
CH646157A5 (en) 1984-11-15
JPS56158774A (en) 1981-12-07
IT8120395A0 (it) 1981-03-18
FR2478634A1 (fr) 1981-09-25
ES8401758A1 (es) 1984-01-01
SE454695B (sv) 1988-05-24
FI810838L (fi) 1981-09-20
SU1158044A3 (ru) 1985-05-23
DK151012C (da) 1988-07-04
FI70011B (fi) 1986-01-31
DE3110817A1 (de) 1982-03-04
FR2478634B1 (sv) 1983-11-10
DK122581A (da) 1981-09-20
YU68981A (en) 1983-10-31
HU180567B (en) 1983-03-28
FI70011C (fi) 1986-09-12
ES511894A0 (es) 1984-01-01
DK151012B (da) 1987-10-12
DK153549B (da) 1988-07-25
BE887954A (fr) 1981-09-16
YU42560B (en) 1988-10-31
ES8302674A1 (es) 1983-02-16
DK153549C (da) 1988-12-05
ES511895A0 (es) 1983-05-01
GB2075009A (en) 1981-11-11
DK151959C (da) 1988-07-11
SU1152518A3 (ru) 1985-04-23
DK151959B (da) 1988-01-18
DK23187A (da) 1987-01-16
IT1211010B (it) 1989-09-29
ES501095A0 (es) 1983-02-16
ES8305340A1 (es) 1983-05-01
GB2075009B (en) 1983-11-30

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Legal Events

Date Code Title Description
MKEX Expiry