CA1152379A - Micropumps - Google Patents
MicropumpsInfo
- Publication number
- CA1152379A CA1152379A CA000358674A CA358674A CA1152379A CA 1152379 A CA1152379 A CA 1152379A CA 000358674 A CA000358674 A CA 000358674A CA 358674 A CA358674 A CA 358674A CA 1152379 A CA1152379 A CA 1152379A
- Authority
- CA
- Canada
- Prior art keywords
- piston
- cylinder
- valve
- liquid
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 239000004033 plastic Substances 0.000 claims abstract description 3
- 229920003023 plastic Polymers 0.000 claims abstract description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000012907 medicinal substance Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0203—Burettes, i.e. for withdrawing and redistributing liquids through different conduits
- B01L3/0206—Burettes, i.e. for withdrawing and redistributing liquids through different conduits of the plunger pump type
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B7/00—Piston machines or pumps characterised by having positively-driven valving
- F04B7/0003—Piston machines or pumps characterised by having positively-driven valving the distribution member forming both the inlet and discharge distributor for one single pumping chamber
- F04B7/0015—Piston machines or pumps characterised by having positively-driven valving the distribution member forming both the inlet and discharge distributor for one single pumping chamber and having a slidable movement
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reciprocating Pumps (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Volume Flow (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Materials For Medical Uses (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Sampling And Sample Adjustment (AREA)
- Details Of Reciprocating Pumps (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
ABSTRACT
A micropump for delivering metered doses of liquid comprises a capillary cylinder in which is movably mounted a piston. The cylinder is mounted in a plastics block with a spool valve slidably movable between first and second positions. In the first position an inlet line communicates with the cylinder chamber and upward movement of the piston causes a column of air and a column of liquid to be drawn in. The valve is then moved to its other position whereby downward movement of the piston expels the metered dose of liquid out through an outlet.
A micropump for delivering metered doses of liquid comprises a capillary cylinder in which is movably mounted a piston. The cylinder is mounted in a plastics block with a spool valve slidably movable between first and second positions. In the first position an inlet line communicates with the cylinder chamber and upward movement of the piston causes a column of air and a column of liquid to be drawn in. The valve is then moved to its other position whereby downward movement of the piston expels the metered dose of liquid out through an outlet.
Description
~5~37~3 This invention relates to micropumps which may be used for the residue-free metering of very small quantities oE liquid. Such pumps may be used, for example, for supplying a regulated quantity of medicinal substance to the atomiser plate of a piezo-electric atomiser. (See for example German Offenlegungsschrift (DE Al) No. 25 37 765, filed August 25, 1975 (Germany), published March 3, 1977, applicant Siemens AG, Berlin, inventor W.-D. Drews).
According to the invention there is provided a micropump for metering small quantities of liquid comprising a capillary cylinder, a gas tight piston disposed in the cylinder for movement between top and bottom dead centre positions, a two-way valve adapted to communicate the cylinder chamber to an inlet and an outlet respectively, and control means adapted to coordinate the piston movements and valve operation such that in the suction stroke first air and second a regulated quantity of liquid are drawn into the cylinder chamber, on reverse movement of the piston to the bottom dead centre position said liquid being delivered through said outlet and said outlet being blown clear in a residue-free manner by the air Eirst drawn into the cylinder chamber.
The valve is preferably a spool valve mounted in a block mounting the cylinder. In a preferred embodiment the cylinder chamber is of such a diameter that ow~ing to capillarity the air column between piston head and liquid is maintained during changes of positlon of the pump.
In order that the -lnvention may be readily understood, an embodiment thereoE will now be described by way of example with reference to the accompanying drawing in which:-Figure 1 is a vertical sectional view of a micropump in accordance with the invention, - 1 - ~
.
.
- ~S2379 Figure 2 is a view similar to Figure 1 showing the pump at a later stage in its cycle o~ operation; and Figure 3 is a vertical part section taken along the line III-III in Figure 1.
-la-' `
' : . . . :
~5Z379 Thc pump comprises a piston 1, preferably of high-grado stecl, movably mounted in a very narrow capillary cylinder 2 which can be made for example of glass or metal. The cylinder 2 terminates in a valve block ~ made for example of a suitable synthetic plastics material such as polytetra1uorethylene, ln which valve spool 5~ made preferably of high-grade steel, can be moved between the stops 6 and 7. The position of the necked portion 8 of the valve slide 5 in relation to the lnlet 9 and out-let 10, respectively, results in a communication between the inlet and outlet, respectively, and the chamb0r ll of the cylinder.
The piston 1 is in its bottom dead centre position when the piston grip 12 abuts the cylinder, as shown in Figure 1. The metered dose is determined by the product of the interior cross sectional area of the cylinder and the stroke between marks a and c.
The movement of the piston l and valve slide 5 is controlled so that the following cycle of action takes place:
ta) With the outlet opened tstop 7 lies a~ainst the valve block) the piston moves out of the position shown in Figure 1 in the direction A
until a certain quantity of air is drawn into the cylinder tthe end face of the piston i5 at mark ~ .
~b) In the second step, communication is made between the inlet 9 ~and consequently the supply vessel) and the cylinder by displacin~ the valve slide in the direction D to the stop 6.
tc) The piston l is moved further in the direction A until the volume of liquid fixed by the stroke and cylinder cross s0ction is drawn in ~final position shown in Figure 2). The end face of the piston is at mark c ~d) The valve slide 5 ls returned in the direction C to the stop 7 so that communication is made between the cylinder 2 and outlet 10.
~S~79 ~ e) The piston 1 moves to the bottom dead centro ~position shown in Figure 1). In so doing, first the liquid and khen the air are driven out of the cylinder 2 and expelled through the outlet line. The air is used to blow free the valve and the outlet line. After this emptying operation the initial position is resumed.
The micro-pump according to the invention serves preerably for metering quantities of liquid in the range rom 10 to 50 ~1, but can also be designed for larger or smaller volumes by changing the dimensions. The use of a sufficiently narrow cylinder ensures that owing to the capillarity the air column between the piston and liquid is maintained even in the case of changes of position of the filled pump.
Mechanical or electrical means known per se serve to control the above-described cycle of action. However, operation o:E the pump can also be controlled by hand. A simple device for the purpose of control consists of a combination of gear wheels, racks and levers composed as follows:
Four gear wheels are arranged next to one another and connected rigidly to one another. The periphe~y of the gear wheels is occupied only par~ly with teeth in such a way that substantially only one gear wheel becomes effective at a certain point in time. Thus, while, for example, the first gear wheel causes the action ~a) via a rack and lever, the other three run freely un~il the desired quantity of air has entered the cylinder.
The second gear wheel then ensures the adjustment of the valve slide, while the first gear wheel simultaneously moves the piston to the top dead centre position. Thenceforward, the third gear wheel brings the valve slide into the outlet position. The fourth gear wheel together with the associated transmission elements thereafter moves ~he piston to the bottom dead centre position. The control mechanism is such that after the gear ,, ' ~ ,~
52;:179 wheels have turned through 360 all the elements arc again situated in the initial position.
In another embodiment of the control device the turning movement is replaced by an ~p-and-down movem~nt. For thls purpose, it may be ad-vantageous to arrange the cylinder and valve so that the directions o movement of ~h~ piston and valve slide run parallel.
_~ _
According to the invention there is provided a micropump for metering small quantities of liquid comprising a capillary cylinder, a gas tight piston disposed in the cylinder for movement between top and bottom dead centre positions, a two-way valve adapted to communicate the cylinder chamber to an inlet and an outlet respectively, and control means adapted to coordinate the piston movements and valve operation such that in the suction stroke first air and second a regulated quantity of liquid are drawn into the cylinder chamber, on reverse movement of the piston to the bottom dead centre position said liquid being delivered through said outlet and said outlet being blown clear in a residue-free manner by the air Eirst drawn into the cylinder chamber.
The valve is preferably a spool valve mounted in a block mounting the cylinder. In a preferred embodiment the cylinder chamber is of such a diameter that ow~ing to capillarity the air column between piston head and liquid is maintained during changes of positlon of the pump.
In order that the -lnvention may be readily understood, an embodiment thereoE will now be described by way of example with reference to the accompanying drawing in which:-Figure 1 is a vertical sectional view of a micropump in accordance with the invention, - 1 - ~
.
.
- ~S2379 Figure 2 is a view similar to Figure 1 showing the pump at a later stage in its cycle o~ operation; and Figure 3 is a vertical part section taken along the line III-III in Figure 1.
-la-' `
' : . . . :
~5Z379 Thc pump comprises a piston 1, preferably of high-grado stecl, movably mounted in a very narrow capillary cylinder 2 which can be made for example of glass or metal. The cylinder 2 terminates in a valve block ~ made for example of a suitable synthetic plastics material such as polytetra1uorethylene, ln which valve spool 5~ made preferably of high-grade steel, can be moved between the stops 6 and 7. The position of the necked portion 8 of the valve slide 5 in relation to the lnlet 9 and out-let 10, respectively, results in a communication between the inlet and outlet, respectively, and the chamb0r ll of the cylinder.
The piston 1 is in its bottom dead centre position when the piston grip 12 abuts the cylinder, as shown in Figure 1. The metered dose is determined by the product of the interior cross sectional area of the cylinder and the stroke between marks a and c.
The movement of the piston l and valve slide 5 is controlled so that the following cycle of action takes place:
ta) With the outlet opened tstop 7 lies a~ainst the valve block) the piston moves out of the position shown in Figure 1 in the direction A
until a certain quantity of air is drawn into the cylinder tthe end face of the piston i5 at mark ~ .
~b) In the second step, communication is made between the inlet 9 ~and consequently the supply vessel) and the cylinder by displacin~ the valve slide in the direction D to the stop 6.
tc) The piston l is moved further in the direction A until the volume of liquid fixed by the stroke and cylinder cross s0ction is drawn in ~final position shown in Figure 2). The end face of the piston is at mark c ~d) The valve slide 5 ls returned in the direction C to the stop 7 so that communication is made between the cylinder 2 and outlet 10.
~S~79 ~ e) The piston 1 moves to the bottom dead centro ~position shown in Figure 1). In so doing, first the liquid and khen the air are driven out of the cylinder 2 and expelled through the outlet line. The air is used to blow free the valve and the outlet line. After this emptying operation the initial position is resumed.
The micro-pump according to the invention serves preerably for metering quantities of liquid in the range rom 10 to 50 ~1, but can also be designed for larger or smaller volumes by changing the dimensions. The use of a sufficiently narrow cylinder ensures that owing to the capillarity the air column between the piston and liquid is maintained even in the case of changes of position of the filled pump.
Mechanical or electrical means known per se serve to control the above-described cycle of action. However, operation o:E the pump can also be controlled by hand. A simple device for the purpose of control consists of a combination of gear wheels, racks and levers composed as follows:
Four gear wheels are arranged next to one another and connected rigidly to one another. The periphe~y of the gear wheels is occupied only par~ly with teeth in such a way that substantially only one gear wheel becomes effective at a certain point in time. Thus, while, for example, the first gear wheel causes the action ~a) via a rack and lever, the other three run freely un~il the desired quantity of air has entered the cylinder.
The second gear wheel then ensures the adjustment of the valve slide, while the first gear wheel simultaneously moves the piston to the top dead centre position. Thenceforward, the third gear wheel brings the valve slide into the outlet position. The fourth gear wheel together with the associated transmission elements thereafter moves ~he piston to the bottom dead centre position. The control mechanism is such that after the gear ,, ' ~ ,~
52;:179 wheels have turned through 360 all the elements arc again situated in the initial position.
In another embodiment of the control device the turning movement is replaced by an ~p-and-down movem~nt. For thls purpose, it may be ad-vantageous to arrange the cylinder and valve so that the directions o movement of ~h~ piston and valve slide run parallel.
_~ _
Claims (5)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. A micropump for metering small quantities of liquid comprising a capillary cylinder, a gas tight piston disposed in the cylinder for movement between top and bottom dead centre positions, a two-way valve adapted to communicate the cylinder chamber to an inlet and an outlet respectively, and control means adapted to coordinate the piston movements and valve operation such that in the suction stroke first air and second a regulated quantity of liquid are drawn into the cylinder chamber, on reverse movement of the piston to the bottom dead centre position said liquid being delivered through said outlet and said outlet being blown clear in a residue-free manner by the air first drawn into the cylinder chamber.
2. A micropump according to claim 1 in which the valve is a spool valve mounted in a block mounting the cylinder.
3. A micropump according to claim 2 in which the valve block is formed of a suitable synthetic plastics material.
4. A micropump according to claim 1, 2 or 3 in which the cylinder chamber is of such a diameter that owing to capillarity the air column between piston head and liquid is maintained during changes of position of the pump.
5. A micropump according to claim 1, 2 or 3 in which the direction of movement of the valve is substantially perpendicular to that of the piston.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792933617 DE2933617A1 (en) | 1979-08-20 | 1979-08-20 | MICRO PISTON PUMP |
| DEP2933617.2 | 1979-08-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1152379A true CA1152379A (en) | 1983-08-23 |
Family
ID=6078839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000358674A Expired CA1152379A (en) | 1979-08-20 | 1980-08-20 | Micropumps |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0024313B1 (en) |
| JP (1) | JPS5632082A (en) |
| AT (1) | ATE4290T1 (en) |
| AU (1) | AU544213B2 (en) |
| CA (1) | CA1152379A (en) |
| DE (2) | DE2933617A1 (en) |
| DK (1) | DK147844C (en) |
| ES (1) | ES494358A0 (en) |
| FI (1) | FI67434C (en) |
| IE (1) | IE50187B1 (en) |
| IL (1) | IL60854A0 (en) |
| NO (1) | NO155358C (en) |
| NZ (1) | NZ194707A (en) |
| ZA (1) | ZA805103B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6520755B1 (en) * | 2000-10-10 | 2003-02-18 | Beckman Coulter, Inc. | Fluid-moving device with integrated valve |
| CN109573124A (en) * | 2018-12-29 | 2019-04-05 | 河南官渡生物工程有限公司 | The plunger pump of adjustable filling amount for veterinary drug production |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE254111C (en) * | ||||
| DE125606C (en) * | ||||
| GB1109492A (en) * | 1964-04-29 | 1968-04-10 | Snam Spa | Improvements in or relating to hydraulic reciprocating pumps |
| JPS4935904A (en) * | 1972-08-09 | 1974-04-03 | ||
| FR2319117A1 (en) * | 1975-07-25 | 1977-02-18 | Pasteur Institut | DEVICE FOR TAKING AND / OR DELIVERY OF LOW DOSE QUANTITIES OF LIQUID |
| US4022065A (en) * | 1976-02-19 | 1977-05-10 | Ramin James A | Calibrated sample delivery apparatus accommodating offset error |
| US4061037A (en) * | 1976-09-20 | 1977-12-06 | Keegan William P | Pipettes |
| US4091677A (en) * | 1976-12-23 | 1978-05-30 | Nichiryo Co., Ltd. | Pipetting apparatus |
| JPS541422A (en) * | 1977-06-06 | 1979-01-08 | Citizen Watch Co Ltd | Fixed quantity of liquid supplying device |
-
1979
- 1979-08-20 DE DE19792933617 patent/DE2933617A1/en not_active Withdrawn
-
1980
- 1980-07-26 AT AT80104407T patent/ATE4290T1/en not_active IP Right Cessation
- 1980-07-26 EP EP80104407A patent/EP0024313B1/en not_active Expired
- 1980-07-26 DE DE8080104407T patent/DE3064407D1/en not_active Expired
- 1980-08-15 NO NO802439A patent/NO155358C/en unknown
- 1980-08-18 FI FI802588A patent/FI67434C/en not_active IP Right Cessation
- 1980-08-18 IL IL60854A patent/IL60854A0/en unknown
- 1980-08-19 ES ES494358A patent/ES494358A0/en active Granted
- 1980-08-19 JP JP11391680A patent/JPS5632082A/en active Pending
- 1980-08-19 NZ NZ194707A patent/NZ194707A/en unknown
- 1980-08-19 AU AU61568/80A patent/AU544213B2/en not_active Ceased
- 1980-08-19 IE IE1752/80A patent/IE50187B1/en unknown
- 1980-08-19 DK DK356980A patent/DK147844C/en not_active IP Right Cessation
- 1980-08-20 ZA ZA00805103A patent/ZA805103B/en unknown
- 1980-08-20 CA CA000358674A patent/CA1152379A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI67434B (en) | 1984-11-30 |
| FI67434C (en) | 1985-03-11 |
| FI802588A (en) | 1981-02-21 |
| IE50187B1 (en) | 1986-03-05 |
| ZA805103B (en) | 1982-04-28 |
| AU6156880A (en) | 1981-04-09 |
| DK147844C (en) | 1985-06-03 |
| ES8105829A1 (en) | 1981-06-16 |
| EP0024313A1 (en) | 1981-03-04 |
| DE3064407D1 (en) | 1983-09-01 |
| NO155358C (en) | 1987-03-18 |
| DK356980A (en) | 1981-02-21 |
| DK147844B (en) | 1984-12-24 |
| AU544213B2 (en) | 1985-05-23 |
| ATE4290T1 (en) | 1983-08-15 |
| ES494358A0 (en) | 1981-06-16 |
| JPS5632082A (en) | 1981-04-01 |
| NO155358B (en) | 1986-12-08 |
| EP0024313B1 (en) | 1983-07-27 |
| NO802439L (en) | 1981-02-23 |
| NZ194707A (en) | 1984-11-09 |
| IE801752L (en) | 1981-02-20 |
| IL60854A0 (en) | 1980-10-26 |
| DE2933617A1 (en) | 1981-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |