BRPI0914301A2 - derivados de pirimidin-4-ona substituída - Google Patents

derivados de pirimidin-4-ona substituída

Info

Publication number: BRPI0914301A2
Authority: BR; Brazil
Prior art keywords: derivatives; substituted pyrimidin; pyrimidin; substituted
Prior art date: 2008-06-26

Application number

BRPI0914301A

Other languages

English (en)

Inventor

Alistair Lochead

Aude Fayol

Julien Vache

Mourad Saady

Philippe Yaiche

Original Assignee

Mitsubishi Tanabe Pharma Corp

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-26

Filing date

2009-06-25

Publication date

2015-10-13

2009-06-25 Application filed by Mitsubishi Tanabe Pharma Corp, Sanofi Aventis filed Critical Mitsubishi Tanabe Pharma Corp

2015-10-13 Publication of BRPI0914301A2 publication Critical patent/BRPI0914301A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Tropical Medicine & Parasitology (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Psychology (AREA)
Immunology (AREA)

BRPI0914301A 2008-06-26 2009-06-25 derivados de pirimidin-4-ona substituída BRPI0914301A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08290613A EP2138492A1 (en)	2008-06-26	2008-06-26	Substituted pyrimidin-4-one derivatives
PCT/IB2009/006576 WO2009156865A1 (en)	2008-06-26	2009-06-25	Substituted pyrimidin-4-one derivatives

Publications (1)

Publication Number	Publication Date
BRPI0914301A2 true BRPI0914301A2 (pt)	2015-10-13

Family

ID=39832598

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0914301A BRPI0914301A2 (pt)	2008-06-26	2009-06-25	derivados de pirimidin-4-ona substituída

Country Status (15)

Country	Link
US (1)	US8614219B2 (pt)
EP (2)	EP2138492A1 (pt)
JP (1)	JP5490790B2 (pt)
KR (1)	KR20110036917A (pt)
CN (1)	CN102076684A (pt)
AR (1)	AR072962A1 (pt)
AU (1)	AU2009263851A1 (pt)
BR (1)	BRPI0914301A2 (pt)
CA (1)	CA2728696A1 (pt)
EA (1)	EA201170099A1 (pt)
IL (1)	IL210172A0 (pt)
MX (1)	MX2010013950A (pt)
NZ (1)	NZ590046A (pt)
TW (1)	TW201004952A (pt)
WO (1)	WO2009156865A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2138494A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
EP2138493A1 (en) *	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138485A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138495A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
EP2138488A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases
EP2138498A1 (en) *	2008-06-26	2009-12-30	sanofi-aventis	Substituted tricyclic derivatives against neurodegenerative diseases
US8530413B2 (en)	2010-06-21	2013-09-10	Sanofi	Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en)	2010-07-05	2012-04-16	Sanofi Sa	(2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en)	2010-07-05	2012-06-01	Sanofi Sa	Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en)	2010-07-05	2012-04-16	Sanofi Aventis	Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (en)	2011-09-12	2013-03-21	Sanofi	6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
CN102993023A (zh) *	2011-09-14	2013-03-27	上海工程技术大学	单取代对位氯代苯胺的制备方法
WO2013045413A1 (en)	2011-09-27	2013-04-04	Sanofi	6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
FR2992316A1 (fr) *	2012-06-22	2013-12-27	Sanofi Sa	Derives de pyrimidinones, leur preparation et leur application en therapeutique
JP7000160B2 (ja) *	2015-05-12	2022-01-19	エフエムシーコーポレーション	除草剤としてのアリール置換二環式化合物
WO2019070044A1 (ja)	2017-10-06	2019-04-11	武田薬品工業株式会社	複素環化合物
JP7250686B2 (ja) *	2017-10-06	2023-04-03	武田薬品工業株式会社	複素環化合物
CN109748914B (zh) *	2018-12-29	2021-05-25	上海珂臻医药科技有限公司	吡啶并嘧啶类化合物及其应用

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EG13192A (en)	1976-02-10	1982-12-31	Rhone Poulenc Ind	Nouveaux derives du dithiole-1,2 leur preparation et les compositions qui les contiennent
HU178496B (en)	1977-12-29	1982-05-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
US4406897A (en)	1981-07-06	1983-09-27	William H. Rorer, Inc.	6-Aryl-4-hydrazinyl-s-triazin-2-ones
US4804663A (en) *	1985-03-27	1989-02-14	Janssen Pharmaceutica N.V.	3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US5629322A (en)	1994-11-15	1997-05-13	Merck & Co., Inc.	Cyclic amidine analogs as inhibitors of nitric oxide synthase
WO1997016430A1 (en)	1995-11-01	1997-05-09	Merck & Co., Inc.	Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
IL123986A (en)	1997-04-24	2011-10-31	Organon Nv	Medicinal compounds
EP1136484A1 (en)	2000-03-23	2001-09-26	Sanofi-Synthelabo	2-(Arylalkylamino)pyrimidone derivatives
CA2665516A1 (en)	2001-04-26	2002-11-07	Daiichi Pharmaceutical Co., Ltd.	Drug efflux pump inhibitor
MXPA04002632A (es)	2001-09-21	2004-07-08	Mitsubishin Pharma Corp	Derivados de 2-pirimidinil-6,7,8,9-tetrahidropirimido-[1,2-a] pirimidin-4-ona y 7-pirimidinil-2,3. dihidroimidazo [1,2-a] pirimidim-5 (1h)-ona substituidos para desordenes neurodegenerativos.
CA2495661C (en)	2002-08-16	2011-06-14	Kinacia Pty Ltd.	Inhibition of phosphoinositide 3-kinase beta
EP1454909B1 (en)	2003-03-07	2008-08-20	Sanofi Aventis	8'-pyridinyl-dihydrospiro (cycloalkyl) -pyrimido (1,2-a) pyrimidin-6-one and 8'-pyrimidinyl-dihydrospiro (cycloalkyl) pyrimido (1,2-a) pyrimidin-6 derivatives -one and their use against neurodegenerative diseases
EP1460076A1 (en) *	2003-03-21	2004-09-22	Sanofi-Synthelabo	Substituted 8-perfluoroalkyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
EP1790649A1 (en) *	2005-11-21	2007-05-30	Sanofi-Aventis	Substituted bicyclic pyrimidone derivatives
EP1939187A1 (en) *	2006-12-20	2008-07-02	Sanofi-Aventis	Substituted heteroaryl pyridopyrimidone derivatives
EP2138485A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted N-Oxide pyrazine derivatives
EP2138493A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted pyrimidone derivatives
EP2138494A1 (en)	2008-06-26	2009-12-30	Sanofi-Aventis	Substituted alkyl pyrimidin-4-one derivatives
EP2138495A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	Substituted pyrimido[2,1-a]isoquinolin-4-one derivatives
EP2138488A1 (en)	2008-06-26	2009-12-30	sanofi-aventis	4-(pyridin-4-yl)-1H-[1,3,5]triazin-2-one derivatives as GSK3-beta inhibitors for the treatment of neurodegenerative diseases

2008
- 2008-06-26 EP EP08290613A patent/EP2138492A1/en not_active Withdrawn
2009
- 2009-06-24 TW TW098121244A patent/TW201004952A/zh unknown
- 2009-06-24 AR ARP090102311A patent/AR072962A1/es unknown
- 2009-06-25 AU AU2009263851A patent/AU2009263851A1/en not_active Abandoned
- 2009-06-25 CA CA2728696A patent/CA2728696A1/en not_active Abandoned
- 2009-06-25 NZ NZ590046A patent/NZ590046A/en not_active IP Right Cessation
- 2009-06-25 MX MX2010013950A patent/MX2010013950A/es not_active Application Discontinuation
- 2009-06-25 CN CN2009801245639A patent/CN102076684A/zh active Pending
- 2009-06-25 EA EA201170099A patent/EA201170099A1/ru unknown
- 2009-06-25 JP JP2011515671A patent/JP5490790B2/ja not_active Expired - Fee Related
- 2009-06-25 EP EP09769676.9A patent/EP2321316B1/en active Active
- 2009-06-25 BR BRPI0914301A patent/BRPI0914301A2/pt not_active IP Right Cessation
- 2009-06-25 KR KR1020117001900A patent/KR20110036917A/ko not_active Withdrawn
- 2009-06-25 WO PCT/IB2009/006576 patent/WO2009156865A1/en active Application Filing
2010
- 2010-12-15 US US12/968,852 patent/US8614219B2/en not_active Expired - Fee Related
- 2010-12-22 IL IL210172A patent/IL210172A0/en unknown

Also Published As

Publication number	Publication date
IL210172A0 (en)	2011-03-31
EP2321316A1 (en)	2011-05-18
EP2138492A1 (en)	2009-12-30
EA201170099A1 (ru)	2011-08-30
KR20110036917A (ko)	2011-04-12
NZ590046A (en)	2011-11-25
CA2728696A1 (en)	2009-12-30
WO2009156865A1 (en)	2009-12-30
AR072962A1 (es)	2010-10-06
TW201004952A (en)	2010-02-01
CN102076684A (zh)	2011-05-25
US20110144132A1 (en)	2011-06-16
MX2010013950A (es)	2011-06-16
US8614219B2 (en)	2013-12-24
JP2011525909A (ja)	2011-09-29
JP5490790B2 (ja)	2014-05-14
AU2009263851A1 (en)	2009-12-30
EP2321316B1 (en)	2014-03-12

Publication	Publication Date	Title
BRPI0914301A2 (pt)	2015-10-13	derivados de pirimidin-4-ona substituída
BRPI0914544A2 (pt)	2015-12-15	derivados de pirimidona substituídos
BRPI0907435A2 (pt)	2015-07-14	Derivados de 5-flúor pirimidina
BRPI0915064A2 (pt)	2015-10-27	derivados de qunoxalinadiona
DK2308877T3 (da)	2014-04-22	Imidazopyridin-2-on-derivater
BRPI0913832A2 (pt)	2015-10-20	derivados de pirrolopiridinilpirimidin-2-ilamina
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI1008749A2 (pt)	2015-08-25	Derivados de benzodiazepina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
BRPI0914657A2 (pt)	2019-09-24	piridin-2-onae piridazin-3-onas substituídas
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
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BR112012002828A2 (pt)	2015-10-13	derivados de 5-fluorpirimidinona
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