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BRPI0911390A2 - sistema de centrifugação de uso único para separação centrífuga de células em uma batelada de cultura celular - Google Patents

sistema de centrifugação de uso único para separação centrífuga de células em uma batelada de cultura celular

Info

Publication number
BRPI0911390A2
BRPI0911390A2 BRPI0911390A BRPI0911390A BRPI0911390A2 BR PI0911390 A2 BRPI0911390 A2 BR PI0911390A2 BR PI0911390 A BRPI0911390 A BR PI0911390A BR PI0911390 A BRPI0911390 A BR PI0911390A BR PI0911390 A2 BRPI0911390 A2 BR PI0911390A2
Authority
BR
Brazil
Prior art keywords
centrifuge system
cell culture
centrifugal
use centrifuge
culture batch
Prior art date
Application number
BRPI0911390A
Other languages
English (en)
Inventor
Stephen B Kessler
Original Assignee
Pneumatic Scale Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pneumatic Scale Corp filed Critical Pneumatic Scale Corp
Publication of BRPI0911390A2 publication Critical patent/BRPI0911390A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2221/00—Applications of separation devices
    • B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Centrifugal Separators (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0911390A 2008-04-22 2009-04-21 sistema de centrifugação de uso único para separação centrífuga de células em uma batelada de cultura celular BRPI0911390A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12503308P 2008-04-22 2008-04-22
PCT/US2009/002464 WO2009131659A1 (en) 2008-04-22 2009-04-21 Single use centrifuge system

Publications (1)

Publication Number Publication Date
BRPI0911390A2 true BRPI0911390A2 (pt) 2015-12-29

Family

ID=41217109

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911390A BRPI0911390A2 (pt) 2008-04-22 2009-04-21 sistema de centrifugação de uso único para separação centrífuga de células em uma batelada de cultura celular

Country Status (8)

Country Link
US (1) US20100167388A1 (pt)
EP (1) EP2285464A4 (pt)
JP (1) JP5329644B2 (pt)
BR (1) BRPI0911390A2 (pt)
CA (2) CA2854413C (pt)
MX (1) MX2010011310A (pt)
RU (1) RU2455078C1 (pt)
WO (1) WO2009131659A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10040077B1 (en) * 2015-05-19 2018-08-07 Pneumatic Scale Corporation Centrifuge system including a control circuit that controls positive back pressure within the centrifuge core
RU2553285C2 (ru) 2010-11-23 2015-06-10 Химонетикс Корпорейшн Ротор для афереза с улучшенными вибрационными характеристиками
CN105664278B (zh) * 2010-11-23 2018-06-29 美国血液技术公司 具有改进振动特征的单采血液成分转筒
US20140324360A1 (en) * 2011-09-21 2014-10-30 Millennium Pharmaceuticals, Inc. Anti-gcc antibody molecules and related compositions and methods
US11878312B2 (en) * 2011-11-21 2024-01-23 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US12350686B2 (en) * 2011-11-21 2025-07-08 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
US11065629B2 (en) * 2011-11-21 2021-07-20 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
GB201207178D0 (en) 2012-04-24 2012-06-06 Bowyer Andrew Miniaturised centrifiguration apparatus
TWI637057B (zh) * 2012-11-09 2018-10-01 拜爾沙納有限公司 具交替生物反應器用途之不連續進料批次製程
WO2015021286A2 (en) * 2013-08-07 2015-02-12 Apd Holdings, Llc Two zone disposable process contact centrifuge for bio-separations
US10125345B2 (en) * 2014-01-31 2018-11-13 Dsm Ip Assets, B.V. Adipose tissue centrifuge and method of use
RU2705959C2 (ru) 2015-05-07 2019-11-12 Биосейф С.А. Устройство, способ и система для непрерывной обработки и разделения биологических текучих сред на компоненты
GB2569168B (en) * 2017-12-08 2022-07-13 Mann & Hummel Gmbh Rotor for a filter sub-assembly
CN110354704B (zh) * 2019-03-14 2021-11-30 中国石油天然气股份有限公司 泡沫生成装置
US11957998B2 (en) * 2019-06-06 2024-04-16 Pneumatic Scale Corporation Centrifuge system for separating cells in suspension
CN115297939A (zh) 2020-03-19 2022-11-04 纽麦迪克斯格尔公司 用于分离悬浊液中的细胞的离心机系统
WO2022120113A1 (en) * 2020-12-04 2022-06-09 Sciperio, Inc Continuously expanding volume bioreactor
CN115970919B (zh) * 2022-12-26 2023-09-26 南京绿岛机械设备有限公司 一种除菌分离机组及其使用方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684361A (en) * 1985-10-11 1987-08-04 Cardiovascular Systems, Inc. Centrifuge
US4086924A (en) * 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus
SU606630A1 (ru) * 1976-10-22 1978-05-15 Специальное Конструкторское Бюро Биофизической Аппаратуры Ротор дл фракционировани крови
SU660718A1 (ru) * 1977-04-25 1979-05-05 Специальное Конструкторское Бюро Биофизической Аппаратуры Ротор дл разделени крови и промывки т желой фракции
US4300717A (en) * 1979-04-02 1981-11-17 Haemonetics Corporation Rotary centrifuge seal
SU1146098A1 (ru) * 1983-05-11 1985-03-23 Специальное Конструкторское Бюро Биофизической Аппаратуры Ротор дл разделени крови и промывки т желой фракции
GB8504880D0 (en) * 1985-02-26 1985-03-27 Ae Plc Disposable cartridges
US4983158A (en) * 1986-07-22 1991-01-08 Haemonetics Corporation Plasmapheresis centrifuge bowl
US4943273A (en) * 1986-07-22 1990-07-24 Haemonetics Corporation Disposable centrifuge bowl for blood processing
DE3771148D1 (de) 1986-07-22 1991-08-08 Haemonetics Corp Zentrifugengehaeuse oder rotor fuer plasmapherese.
CA1334190C (en) * 1988-10-07 1995-01-31 T. Michael Dennehey High volume centrifugal fluid processing system and method for cultured cell suspensions and the like
US4936820A (en) * 1988-10-07 1990-06-26 Baxter International Inc. High volume centrifugal fluid processing system and method for cultured cell suspensions and the like
WO1994008721A1 (en) * 1992-10-13 1994-04-28 Haemonetics Corporation Disposable centrifuge rotor and core
CH687505A5 (fr) * 1993-01-29 1996-12-31 Elp Rochat Séparateur centrifuge pour fluides.
JP3313572B2 (ja) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション 血液処理用遠心分離器ボウル
US5919125A (en) * 1997-07-11 1999-07-06 Cobe Laboratories, Inc. Centrifuge bowl for autologous blood salvage
WO2001076759A1 (en) * 2000-04-11 2001-10-18 Medicept, Inc. Sealed centrifugal clarifier
DE60139796D1 (de) 2000-05-19 2009-10-15 Pneumatic Scale Corp Zuführeinrichtung mit geringer scherkraft für zentrifugen
US6458067B1 (en) * 2000-06-30 2002-10-01 Beckman Coulter, Inc. Removable conformal liners for centrifuge containers
US20040217069A1 (en) * 2003-04-30 2004-11-04 Immunicon Corp. Rotor assembly for the collection, separation, and sampling of rare blood cells
DE10334370A1 (de) * 2003-07-25 2005-02-24 Westfalia Separator Ag Vollmantel-Schneckenzentrifuge mit Direktantrieb
DE10336350B4 (de) * 2003-08-08 2007-10-31 Westfalia Separator Ag Vollmantel-Schneckenzentrifuge, mit Schälscheibe

Also Published As

Publication number Publication date
RU2010147384A (ru) 2012-05-27
CA2854413A1 (en) 2009-10-29
RU2455078C1 (ru) 2012-07-10
EP2285464A1 (en) 2011-02-23
JP5329644B2 (ja) 2013-10-30
MX2010011310A (es) 2011-02-15
US20100167388A1 (en) 2010-07-01
JP2011517958A (ja) 2011-06-23
CA2721984A1 (en) 2009-10-29
CA2721984C (en) 2014-09-02
CA2854413C (en) 2016-12-13
EP2285464A4 (en) 2014-01-01
WO2009131659A1 (en) 2009-10-29

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE 6A. E 7A. ANUIDAE(S)

B08G Application fees: restoration
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06T Formal requirements before examination

Free format text: O DEPOSITANTE DEVE RESPONDER A EXIGENCIA FORMULADA NESTE PARECER EM ATE 60 (SESSENTA) DIAS, A PARTIR DA DATA DE PUBLICACAO NA RPI, SOB PENA DO ARQUIVAMENTO DO PEDIDO, DE ACORDO COM O ARTIGO 34, INCISO II, DA LPI, POR MEIO DO SERVICO DE CODIGO 206.PUBLIQUE-SE A EXIGENCIA (6.20).

B07A Technical examination (opinion): publication of technical examination (opinion)
B09B Decision: refusal
B12B Appeal: appeal against refusal