[go: up one dir, main page]

BRPI0909791A8 - Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor. - Google Patents

Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor.

Info

Publication number
BRPI0909791A8
BRPI0909791A8 BRPI0909791A BRPI0909791A BRPI0909791A8 BR PI0909791 A8 BRPI0909791 A8 BR PI0909791A8 BR PI0909791 A BRPI0909791 A BR PI0909791A BR PI0909791 A BRPI0909791 A BR PI0909791A BR PI0909791 A8 BRPI0909791 A8 BR PI0909791A8
Authority
BR
Brazil
Prior art keywords
cartridge
sensing device
target components
liquid sample
detecting target
Prior art date
Application number
BRPI0909791A
Other languages
English (en)
Inventor
J J Sijbers Mara
J W Van Lankvelt Petrus
K De Theije Femke
H Nieuwenhuis Jeroen
Original Assignee
Koninklije Philips Electronics N V
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklije Philips Electronics N V, Koninklijke Philips Nv filed Critical Koninklije Philips Electronics N V
Publication of BRPI0909791A2 publication Critical patent/BRPI0909791A2/pt
Publication of BRPI0909791A8 publication Critical patent/BRPI0909791A8/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/282—Magnetic plugs and dipsticks with associated accumulation indicator, e.g. Hall sensor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/946—CNS-stimulants, e.g. cocaine, amphetamines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/18—Magnetic separation whereby the particles are suspended in a liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrochemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

CARTUCHO, DISPOSITIVO SENSOR E MÉTODO PARA DETECÇÃO DE COMPONENTES ALVO EM UMA AMOSTRA LÍQUIDA, E, USO DO CARTUCHO OU DO DISPOSITIVO SENSOR. A invenção diz respeito a um cartucho (100) e um correspondente dispositivo sensor para a detecção de componentes-alvo em uma amostra líquida. O cartucho (100) compreende uma câmara de amostra (SC), pelo menos, dois reservatórios (131, 132) que podem ser fornecidos com partículas magnéticas (MP, MP'), e, pelo menos duas correspondentes zonas sensitivas (121, 122) nas quais as partículas magnéticas dissolvidas e/ou os componentes-alvo podem ser detectados. Quando um campo de acionamento magnético (B) de uma dada configuração é estabelecido na câmara de amostra, as partículas magnéticas de diferentes reservatórios migram predominantemente para diferentes zonas sensitivas. Desta forma, a mistura de partículas magnéticas pode ser evitada.
BRPI0909791A 2008-03-17 2009-03-11 Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor. BRPI0909791A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08102671 2008-03-17
PCT/IB2009/051021 WO2009115951A1 (en) 2008-03-17 2009-03-11 Cartridge for assays with magnetic particles

Publications (2)

Publication Number Publication Date
BRPI0909791A2 BRPI0909791A2 (pt) 2015-08-11
BRPI0909791A8 true BRPI0909791A8 (pt) 2016-08-02

Family

ID=40641647

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0909791A BRPI0909791A8 (pt) 2008-03-17 2009-03-11 Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor.

Country Status (8)

Country Link
US (2) US20110014719A1 (pt)
EP (1) EP2263084B1 (pt)
JP (1) JP5628784B2 (pt)
CN (1) CN101978267B (pt)
BR (1) BRPI0909791A8 (pt)
RU (1) RU2505816C2 (pt)
WO (1) WO2009115951A1 (pt)
ZA (1) ZA201007366B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2329269A1 (en) * 2008-09-26 2011-06-08 Koninklijke Philips Electronics N.V. Magnetic-label sensor and cartridge
EP2344887A1 (en) * 2008-10-31 2011-07-20 Koninklijke Philips Electronics N.V. Biosensor with multi-chamber cartridge
US9086396B2 (en) * 2008-11-28 2015-07-21 Roche Molecular Systems, Inc. System and method for the automated processing of fluids, method for determining the matching of objects
EP2480887B1 (en) 2009-09-23 2015-12-16 Koninklijke Philips N.V. Binding assay with multiple magnetically labelled tracer binding agents
CN102656443B (zh) * 2009-12-18 2016-01-20 皇家飞利浦电子股份有限公司 物质确定设备
EP2586041A1 (en) * 2010-06-22 2013-05-01 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
BR112013000017A2 (pt) * 2010-07-05 2016-05-24 Koninkl Philips Electronics Nv mátodo para exame de uma amostra em um cartucho com uma entrada e uma câmara de reação, cartucho para exame de uma amostra e aparalho para exame de uma amostra
WO2012073182A1 (en) 2010-11-30 2012-06-07 Koninklijke Philips Electronics N.V. A sensor device for magnetically actuated particles
EP2541230A1 (en) * 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Detection of clusters of magnetic particles
EP2800970B1 (en) 2012-01-04 2016-09-28 Magnomics, S.A. Monolithic device combining cmos with magnetoresistive sensors
EP2805164B1 (en) * 2012-01-16 2017-11-08 Koninklijke Philips N.V. Determining a presence of target molecules in a body fluid comprising cells
CN102600967A (zh) * 2012-03-06 2012-07-25 南昌大学 一种智能控制磁分离器
CN102600966A (zh) * 2012-03-06 2012-07-25 南昌大学 简易磁珠分离装置
WO2014062719A2 (en) 2012-10-15 2014-04-24 Nanocellect Biomedical, Inc. Systems, apparatus, and methods for sorting particles
CN102935996B (zh) * 2012-10-18 2015-04-22 上海交通大学 血清肿瘤标志物检测的微型化磁通门生物传感器制作方法
JP2014232032A (ja) * 2013-05-29 2014-12-11 独立行政法人国立長寿医療研究センター 化学・物理現象検出方法及びその装置
RU2569766C2 (ru) * 2014-01-24 2015-11-27 Общество с ограниченной ответственностью "Химмотолог" Устройство для автоматического определения качества смазочных материалов
CN104407113B (zh) * 2014-11-04 2016-09-07 上海交通大学 食品中致病菌检测的微型化磁通门生物传感器
CN107407675B (zh) * 2015-03-26 2020-03-17 皇家飞利浦有限公司 生物传感器盒的制造
US10261076B2 (en) * 2015-10-02 2019-04-16 The Board Of Trustees Of The Leland Stanford Junior University Method for detecting small molecule analytes using magnetoresistant sensors
US9702748B2 (en) 2015-10-14 2017-07-11 International Business Machines Corporation Graphene-based magnetic hall sensor for fluid flow analysis at nanoscale level
EP3427043B1 (en) * 2016-03-11 2024-08-28 Zomedica Biotechnologies LLC Baw sensor fluidic device with increased dynamic measurement range
EP3928870A4 (en) * 2019-02-22 2022-11-23 TDK Corporation BLOOD PURIFICATION DEVICE AND BLOOD PURIFICATION METHOD
US11977086B2 (en) 2019-03-21 2024-05-07 Hound Labs, Inc. Biomarker detection from breath samples
GB2631114A (en) * 2023-06-20 2024-12-25 Tachmed Holdings Ltd Sensor unit

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846708A (en) 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
US5981297A (en) * 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US6300138B1 (en) * 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
US7390675B2 (en) * 1999-10-15 2008-06-24 Christopher Feistel Multi-functional and configurable assay
US6875619B2 (en) * 1999-11-12 2005-04-05 Motorola, Inc. Microfluidic devices comprising biochannels
AU2002210291A1 (en) * 2000-08-21 2002-03-22 Oleg N. Darashkevitch Method and device for simultaneous detection of multiple components in a mixture
US7232691B2 (en) * 2001-11-27 2007-06-19 Los Alamos National Security, Llc Bioassay and biomolecular identification, sorting, and collection methods using magnetic microspheres
CN100516879C (zh) * 2002-01-29 2009-07-22 旭化成株式会社 生物传感器、用于磁性分子以及待测量目标的测量方法
US20060134713A1 (en) * 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US20040197845A1 (en) * 2002-08-30 2004-10-07 Arjang Hassibi Methods and apparatus for pathogen detection, identification and/or quantification
CN1829922B (zh) 2003-07-30 2010-06-16 皇家飞利浦电子股份有限公司 具有改进信噪比的芯片内磁性粒子传感器
EP1697755A1 (en) 2003-07-30 2006-09-06 Koninklijke Philips Electronics N.V. On-chip magnetic sensor device with suppressed cross-talk
JP2005315677A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出装置および検出方法
JP4680587B2 (ja) * 2004-12-28 2011-05-11 旭化成株式会社 バイオセンサ、対象物測定方法、バイオセンサ用カートリッジ及び不織布
US8828740B2 (en) 2005-01-31 2014-09-09 Koninklijke Philips N.V. Rapid and sensitive biosensing
KR101322943B1 (ko) * 2005-05-09 2013-10-29 테라노스, 인코포레이티드 현장진료 유체 시스템 및 그 용도
RU2415432C2 (ru) * 2005-06-17 2011-03-27 Конинклейке Филипс Электроникс Н.В. Точный магнитный биодатчик
US20070031283A1 (en) * 2005-06-23 2007-02-08 Davis Charles Q Assay cartridges and methods for point of care instruments
JP5188091B2 (ja) * 2006-03-31 2013-04-24 キヤノン株式会社 センサ素子、ならびにこの素子を用いた磁性粒子の検出方法及び標的物質の検出方法
CN101438142B (zh) * 2006-05-10 2013-10-30 皇家飞利浦电子股份有限公司 快速磁生物传感器
CN101021530B (zh) * 2007-03-26 2011-08-31 南京大学 自动化通道分辨化学发光多组分免疫检测系统及分析方法
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
EP2034324A3 (en) * 2007-07-20 2010-06-16 Koninklijke Philips Electronics N.V. Sensor cartridge

Also Published As

Publication number Publication date
US20110014719A1 (en) 2011-01-20
RU2010142278A (ru) 2012-04-27
WO2009115951A1 (en) 2009-09-24
CN101978267A (zh) 2011-02-16
EP2263084B1 (en) 2017-02-22
ZA201007366B (en) 2012-03-28
JP2011516832A (ja) 2011-05-26
RU2505816C2 (ru) 2014-01-27
US10006907B2 (en) 2018-06-26
BRPI0909791A2 (pt) 2015-08-11
JP5628784B2 (ja) 2014-11-19
CN101978267B (zh) 2017-04-26
US20160291004A1 (en) 2016-10-06
EP2263084A1 (en) 2010-12-22

Similar Documents

Publication Publication Date Title
BRPI0909791A8 (pt) Cartucho, dispositivo sensor e método para detecção de componentes alvo em uma amostra líquida, e, uso do cartucho ou do dispositivo sensor.
MX374652B (es) Ensayos para detectar la presencia o la cantidad de un anticuerpo antifármaco.
CA2818940C (en) Method and apparatus for determination of system parameters for reducing crude unit corrosion
BR112018069849A2 (pt) kit, dispositivo e método para a detecção de câncer pancreático precoce ou de lesão precursora do câncer pancreático
BR112012033783A2 (pt) aparelho para detectar uma doença em um material biológico, aparelho que compreende dois microdispositivos, microdispositivo, aparelho para interagir com um material biológico, e, métodos para a fabricação de um microdispositivo, para detectar uma doença na sua fase inicial em um primeiro material, e para detectar informação dinâmica de um material biológico
BR112018000851A2 (pt) sistemas e métodos para detecção e quantificação aprimoradas de analitos
BR112017026253A2 (pt) aparelho para a detecção de um material vazado, sistema de detecção de material vazado, uso do aparelho e método de detecção de um material vazado
BR112012009855A2 (pt) métodos para determinar uma quantidade eficaz de uma droga, para otimizar a terapia e/ou reduzir as toxicidade a uma droga, para determinar a presença ou nível de uma droga, para otimizar a quantidade terapêutica de uma droga e para determinar a presença ou nível de um autoanticorpo para uma droga, e, kit
BR112016001702A2 (pt) cartucho fluídico para amplificação e detecção de ácido nucleico
BRPI0814088A2 (pt) Dispositivo sensor magnético, uso do mesmo, chip sensor magnético, método para determinar a presença e/ou quantidade de porções alvo em um fluido de amostra, e, produto de programa de computador
JOP20200216A1 (ar) تجارب للكشف عن التنكس العصبي
BRPI0814380A2 (pt) Cartucho de sensor, uso de um cartucho de sensor, métodos para fabricar um cartucho de sensor, e para determinar a presença e/ou quantidade de pelo menos dois diferentes componentes alvo em um fluido de amostra, e, uso do método
BR112015001536A2 (pt) sistema e métodos para levar em conta os interferentes em um biossensor de glicose
BRPI0907020A2 (pt) Dispositivo sensor de concentração, dispositivo de cálculo da relação de mistura, métodos para calcular uma ralação de mistura do líquido de mistura e para detectar concentrações do fluido e, dispositivo de detecção de concentração
CO6680668A2 (es) Ensayos biomarcadores para detectar o medir inhibición de actividad quinasa tor
EP2681542A4 (en) NANOPORENT DEVICE FOR REVERSIBLE ION AND MOLECULAR DETECTION OR MIGRATION
BRPI0923199B8 (pt) método para determinar a presença de anticorpos de fixação de complemento
BR112016021678A2 (pt) método e sistema para determinar uma janela de peso de lama em um poço, e, meio legível por computador.
BR112016006617A2 (pt) método, sistema e meio legível por computador não transitório
IN2014DE01077A (pt)
WO2012075076A3 (en) Method and apparatus for determination of system parameters for reducing crude unit corrosion
BR112016026994A8 (pt) estimativa de molhabilidade com o uso de ressonância magnética
BR112019000534A2 (pt) método para determinar o uso de um veículo, meio legível por máquina não transitório, dispositivo para afixar a um veículo e kit
BR112015017179A8 (pt) método de avaliação de um gradiente de uma composição dos materiais em um reservatório de petróleo, e método de avaliação de um gradiente de uma composição dos materiais
MX2019011977A (es) Composiciones y sistemas para la determinacion de la funcion renal.

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B25G Requested change of headquarter approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]