[go: up one dir, main page]

BRPI0821915A2 - Cyclic pyridyl-n- (1,3,4) -thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and use as pharmaceuticals - Google Patents

Cyclic pyridyl-n- (1,3,4) -thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and use as pharmaceuticals

Info

Publication number
BRPI0821915A2
BRPI0821915A2 BRPI0821915-0A BRPI0821915A BRPI0821915A2 BR PI0821915 A2 BRPI0821915 A2 BR PI0821915A2 BR PI0821915 A BRPI0821915 A BR PI0821915A BR PI0821915 A2 BRPI0821915 A2 BR PI0821915A2
Authority
BR
Brazil
Prior art keywords
thiadiazol
pharmaceuticals
processes
preparation
benzene sulfonamides
Prior art date
Application number
BRPI0821915-0A
Other languages
Portuguese (pt)
Inventor
Karl Schoenafinger
Stefanie Keil
Matthias Urmann
Hans Matter
Maike Glien
Wolfgang Wendler
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0821915A2 publication Critical patent/BRPI0821915A2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
BRPI0821915-0A 2007-12-26 2008-12-12 Cyclic pyridyl-n- (1,3,4) -thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and use as pharmaceuticals BRPI0821915A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07291626 2007-12-26
PCT/EP2008/010559 WO2009080223A1 (en) 2007-12-26 2008-12-12 Cyclic pyridyl-n-(1,3,4)-thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
BRPI0821915A2 true BRPI0821915A2 (en) 2015-06-16

Family

ID=39356534

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821915-0A BRPI0821915A2 (en) 2007-12-26 2008-12-12 Cyclic pyridyl-n- (1,3,4) -thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and use as pharmaceuticals

Country Status (14)

Country Link
US (1) US8344004B2 (en)
EP (1) EP2240474B1 (en)
JP (1) JP2011507914A (en)
KR (1) KR20100101165A (en)
CN (1) CN101910162A (en)
AR (1) AR072041A1 (en)
AT (1) ATE549332T1 (en)
AU (1) AU2008340756A1 (en)
BR (1) BRPI0821915A2 (en)
CA (1) CA2710441A1 (en)
IL (1) IL206531A0 (en)
MX (1) MX2010006647A (en)
TW (1) TW200940536A (en)
WO (1) WO2009080223A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007310897A1 (en) * 2006-10-25 2008-05-02 Neurosearch A/S Oxadiazole and thiadiazole compounds and their use as nicotinic acetylcholine receptor modulators
WO2011107494A1 (en) 2010-03-03 2011-09-09 Sanofi Novel aromatic glycoside derivatives, medicaments containing said compounds, and the use thereof
CA2798330A1 (en) 2010-05-05 2011-11-10 Infinity Pharmaceuticals, Inc. Tetrazolones as inhibitors of fatty acid synthase
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
TWI754702B (en) * 2016-12-28 2022-02-11 德商Ucb製藥有限公司 (aza)indole- and benzofuran-3-sulfonamides
US20200206309A1 (en) * 2017-07-27 2020-07-02 The Mclean Hospital Corporation METHODS AND COMPOSITIONS RELATED TO THE TREATMENT OF NURR1- AND PPARy-MEDIATED CONDITIONS
GB201810092D0 (en) 2018-06-20 2018-08-08 Ctxt Pty Ltd Compounds
GB201810581D0 (en) 2018-06-28 2018-08-15 Ctxt Pty Ltd Compounds
AU2020296361A1 (en) 2019-06-18 2022-01-06 Ctxt Pty Ltd Benzisoxazole sulfonamide derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522638A1 (en) * 1985-06-25 1987-01-08 Diamalt Ag NEW SOMATOSTATIN DERIVATIVES
WO1997040017A2 (en) 1996-04-19 1997-10-30 Novo Nordisk A/S Modulators of molecules with phosphotyrosine recognition units
MXPA06000118A (en) 2003-07-08 2006-04-27 Novartis Ag Benzenesulfonylamino compounds and pharmaceutical compositions containing these compounds.
CN101282952A (en) 2005-10-06 2008-10-08 塞诺菲-安万特股份有限公司 Cyclic N- [1,3,4] -thiadiazol-2-yl-benzene sulfonamides, process for their preparation and their use as pharmaceuticals
CN101277940A (en) 2005-10-06 2008-10-01 塞诺菲-安万特股份有限公司 4-Oxy-N-[1,3,4]-thiadiazol-2-yl-benzenesulfonamides, their preparation and their use as medicaments

Also Published As

Publication number Publication date
US20110224263A1 (en) 2011-09-15
EP2240474A1 (en) 2010-10-20
EP2240474B1 (en) 2012-03-14
AU2008340756A1 (en) 2009-07-02
WO2009080223A1 (en) 2009-07-02
JP2011507914A (en) 2011-03-10
MX2010006647A (en) 2010-08-17
ATE549332T1 (en) 2012-03-15
CA2710441A1 (en) 2009-07-02
CN101910162A (en) 2010-12-08
AR072041A1 (en) 2010-08-04
US8344004B2 (en) 2013-01-01
TW200940536A (en) 2009-10-01
KR20100101165A (en) 2010-09-16
IL206531A0 (en) 2010-12-30

Similar Documents

Publication Publication Date Title
BRPI0821915A2 (en) Cyclic pyridyl-n- (1,3,4) -thiadiazol-2-yl-benzene sulfonamides, processes for their preparation and use as pharmaceuticals
BRPI0914978A2 (en) Oxadiazolone-core-group-reinforced n-heterocyclic sulfonamides, processes for their preparation and use as pharmaceuticals
BRPI1010621A2 (en) imidazoquinolinones derivative, their pharmaceutical composition and their use
BRPI0821276A2 (en) Product and product use
BRPI0918502A2 (en) substituted aminoindans and analogs thereof, and their pharmaceutical use
BRPI1009481A2 (en) substituted 2-acetamido-5-aryl-1,2,4-triazolones compounds, their preparation process, their use and medicament comprising the same
BR112013016772A2 (en) compound, compound use, pharmaceutical composition, oligonucleotide and conjugate
BRPI0912356A2 (en) sirtuin modulating compounds, pharmaceutical composition comprising them and their use
BRPI0808098A2 (en) 4-ARYL-1,4-DI-HYDRO-1,6-NAPHTHRIDINAMIDS REPLACED AND THEIR USE
BRPI1008740A2 (en) Pesticide proteins and methods for their use.
BR112012004335A2 (en) compound, pharmaceutical composition, and use of the compound.
BRPI0919810A2 (en) nitrogen-containing heterocyclic compounds, their preparation and their use as antibacterial medicines
BR112013023174A2 (en) "c4-monomethyl triterpenoid-derived compounds, pharmaceutical composition comprising said compounds and use thereof"
BRPI1014583A2 (en) heterocyclic sulfonamides, pharmaceutical compositions and uses thereof.
BRPI1011043A2 (en) phenylurea compounds and substituted phenylamides as vanyloid receptor ligands, their pharmaceutical composition, their use and their preparation process.
BRPI0818459A2 (en) Pharmaceutical composition suitable for ophthalmic use.
BRPI0813680A2 (en) IRNA AGENTS, PHARMACEUTICAL COMPOSITION UNDERSTANDING THE SAME, AS WELL AS USE.
BRPI0806589A2 (en) CATALYST, ITS PREPARATION AND USE.
BRPI0813455A2 (en) 17BETA-CYAN-18A-HOMO-19-NOR-ANDROST-4-ENO DERIVATIVE, ITS USE AND MEDICINAL PRODUCTS CONTAINING THIS DERIVATIVE.
BRPI0808798A2 (en) 3,5-DISSUBSTITUTED PHENOXYPHENYLAMIDINS AND THEIR USE AS FUNGICIDES
BRPI0807078A2 (en) COMPOUND AND PHARMACEUTICAL FORMULATION
BRPI0915552A2 (en) cyclosporine derivatives, their use and pharmaceutical composition
BRPI0810654A2 (en) Thiadiazolyloxyphenylamidines and their use as fungicides.
BRPI0919807A2 (en) heterocyclic nitrogenous compounds, their preparation and their use as antibacterial medicines
BR112013003530A2 (en) '' pharmaceutical, kit, use and preparations ''

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 3A, 4A, 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.