BRPI0816158A2 - composto carbociclo fundido substituído com heterociclila e uso do mesmo. - Google Patents

composto carbociclo fundido substituído com heterociclila e uso do mesmo.

Info

Publication number: BRPI0816158A2
Authority: BR; Brazil
Prior art keywords: heterocyclyl; substituted fused; fused carbocycle; compound; carbocycle compound
Prior art date: 2007-08-15

Application number

BRPI0816158A

Other languages

English (en)

Inventor

W Gil Daniel

Chow Ken

E Garst Michael

C Sinha Santosh

S Bhat Smita

M Heidelbaugh Todd

Original Assignee

Allergan Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-15

Filing date

2008-08-14

Publication date

2017-06-13

2008-08-14 Application filed by Allergan Inc filed Critical Allergan Inc

2017-06-13 Publication of BRPI0816158A2 publication Critical patent/BRPI0816158A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI0816158A 2007-08-15 2008-08-14 composto carbociclo fundido substituído com heterociclila e uso do mesmo. BRPI0816158A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US95597207P	2007-08-15	2007-08-15
PCT/US2008/073110 WO2009023758A1 (en)	2007-08-15	2008-08-14	Heterocyclyl substituted fused carbocyles useful in the treatment of conditions such as glaucoma and pain

Publications (1)

Publication Number	Publication Date
BRPI0816158A2 true BRPI0816158A2 (pt)	2017-06-13

Family

ID=39865281

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0816158A BRPI0816158A2 (pt)	2007-08-15	2008-08-14	composto carbociclo fundido substituído com heterociclila e uso do mesmo.

Country Status (10)

Country	Link
US (2)	US8426454B2 (pt)
EP (1)	EP2188262A1 (pt)
JP (1)	JP2010536781A (pt)
KR (1)	KR20100071990A (pt)
CN (1)	CN101855212A (pt)
AU (1)	AU2008286824B2 (pt)
BR (1)	BRPI0816158A2 (pt)
CA (1)	CA2696315A1 (pt)
RU (1)	RU2481335C2 (pt)
WO (1)	WO2009023758A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101855212A (zh)	2007-08-15	2010-10-06	阿勒根公司	可用于治疗例如青光眼和疼痛的病症的杂环取代的稠合碳环
JP2010536780A (ja) *	2007-08-15	2010-12-02	アラーガンインコーポレイテッド	治療化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2870161A (en)	1957-07-08	1959-01-20	Pfizer & Co C	2-(1-indanyl amino)-oxazolines
US2870159A (en) *	1957-07-08	1959-01-20	Pfizer & Co C	Hydrogenated 2-(1-naphthylamino)-oxazolines
US2883410A (en)	1957-07-08	1959-04-21	Pfizer & Co C	N-(1-indanyl)-n'-(beta-substituted ethyl)-ureas
US3636219A (en) *	1964-03-02	1972-01-18	Du Pont	Anticholinergic compositions containing certain thiazolines or imidazolines
DE1963192A1 (de)	1969-12-17	1971-06-24	Bayer Ag	Ektoparasiticide Mittel
AT330769B (de) *	1974-04-05	1976-07-26	Chemie Linz Ag	Verfahren zur herstellung von 2-arylamino- 2-imidazolin-derivaten und ihren salzen
US4256755A (en) *	1980-04-28	1981-03-17	E. I. Du Pont De Nemours & Company	Method of using N-substituted dihydro-2-oxazolamines as analgesics
GB8610909D0 (en) *	1986-05-03	1986-06-11	Beecham Group Plc	Compounds
DE19514579A1 (de) *	1995-04-20	1996-10-24	Boehringer Ingelheim Kg	Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
JPH11505224A (ja) *	1995-05-12	1999-05-18	アラーガン	心臓血管系副作用を伴わないα▲下２▼アドレナリン作動剤として有用なアリール−イミダゾリンおよびアリール−イミダゾール
US7141597B2 (en)	2003-09-12	2006-11-28	Allergan, Inc.	Nonsedating α-2 agonists
JPWO2005055999A1 (ja) *	2003-12-08	2007-07-05	日本新薬株式会社	抗コリン作用剤
GB0516706D0 (en) *	2005-08-15	2005-09-21	Syngenta Participations Ag	Chemical compounds
PE20070705A1 (es) *	2005-11-25	2007-08-23	Basf Ag	Compuestos de indanil - y tetrahidronaftil-amino-azolina para combatir pestes animales
AU2007214826A1 (en) *	2006-02-15	2007-08-23	Bayer Cropscience Ag	Insecticidal substituted amino heterocyclic and heteroaryl derivatives
WO2008115141A1 (en) *	2007-03-19	2008-09-25	Albireo Ab	4, 5-dihydro-1,3-thiazol-2-amine derivatives and their use in the treatment of respiratory, cardiovascular, neurological or gastrointestinal disorders
CN101855212A (zh)	2007-08-15	2010-10-06	阿勒根公司	可用于治疗例如青光眼和疼痛的病症的杂环取代的稠合碳环
JP2010536780A (ja) *	2007-08-15	2010-12-02	アラーガンインコーポレイテッド	治療化合物

2008
- 2008-08-14 CN CN200880109727A patent/CN101855212A/zh active Pending
- 2008-08-14 AU AU2008286824A patent/AU2008286824B2/en not_active Ceased
- 2008-08-14 JP JP2010521170A patent/JP2010536781A/ja active Pending
- 2008-08-14 KR KR1020107005728A patent/KR20100071990A/ko not_active Withdrawn
- 2008-08-14 US US12/673,351 patent/US8426454B2/en not_active Expired - Fee Related
- 2008-08-14 EP EP08797859A patent/EP2188262A1/en not_active Withdrawn
- 2008-08-14 RU RU2010108386/04A patent/RU2481335C2/ru not_active IP Right Cessation
- 2008-08-14 CA CA2696315A patent/CA2696315A1/en not_active Abandoned
- 2008-08-14 BR BRPI0816158A patent/BRPI0816158A2/pt not_active IP Right Cessation
- 2008-08-14 WO PCT/US2008/073110 patent/WO2009023758A1/en active Application Filing
2013
- 2013-03-29 US US13/853,160 patent/US8815923B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US20110178144A1 (en)	2011-07-21
RU2481335C2 (ru)	2013-05-10
CN101855212A (zh)	2010-10-06
US8426454B2 (en)	2013-04-23
EP2188262A1 (en)	2010-05-26
AU2008286824A1 (en)	2009-02-19
AU2008286824B2 (en)	2014-10-02
US8815923B2 (en)	2014-08-26
JP2010536781A (ja)	2010-12-02
CA2696315A1 (en)	2009-02-19
RU2010108386A (ru)	2011-09-20
US20130217739A1 (en)	2013-08-22
KR20100071990A (ko)	2010-06-29
WO2009023758A1 (en)	2009-02-19

Publication	Publication Date	Title
BRPI0821668A2 (pt)	2015-06-16	Uso
BRPI0807388A2 (pt)	2014-05-20	Instrumento de escrita termocromática.
FR2909857B1 (fr)	2009-03-06	Endovalve.
ATE513831T1 (de)	2011-07-15	Pyridinä3,4-büpyrazinone
ATE490873T1 (de)	2010-12-15	Ringordnermechanismus
DE602006016993D1 (de)	2010-10-28	Gleitelement
BRPI0807991A2 (pt)	2014-06-17	Anticorpos anti-il-23r elaborados.
FR2900034B1 (fr)	2012-08-17	Poudrier.
DE112006004211A5 (de)	2009-12-03	Bohrfutter
DE602007009260D1 (de)	2010-10-28	Zwischenhülse
EP2202090A4 (en)	2010-12-08	MECHANICAL PIN
DE112007003149A5 (de)	2009-09-24	Spannfutter
BRPI0818645A2 (pt)	2015-04-07	Lápis
DE112007000530A5 (de)	2008-12-04	Kopfplatte
FR2923713B1 (fr)	2010-09-10	Composition reductrice epaissie.
FR2913338B1 (fr)	2009-07-24	Composition de rehydratation.
BRPI0816158A2 (pt)	2017-06-13	composto carbociclo fundido substituído com heterociclila e uso do mesmo.
ATE488416T1 (de)	2010-12-15	Bob
DE112007001763A5 (de)	2009-09-24	Schaltungsanordnung
ITCE20060002A1 (it)	2007-09-11	Patok.
ES1062424Y (es)	2006-09-16	Sombrilla.
FI7246U1 (fi)	2006-10-18	Kynä
TH94168B (th)	2009-03-13	ปากกา
FIU20060430U0 (fi)	2006-10-12	Järjestelijä
ES1060537Y (es)	2006-01-16	Boligrafo

Legal Events

Date	Code	Title	Description
2017-06-27	B08F	Application fees: dismissal - article 86 of industrial property law
2017-10-24	B08K	Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)