BRPI0813981A2 - agonistas sintéticos da tlr9. - Google Patents

agonistas sintéticos da tlr9.

Info

Publication number: BRPI0813981A2
Authority: BR; Brazil
Prior art keywords: tlr9; synthetic agonists; agonists; synthetic
Prior art date: 2007-08-01

Application number

BRPI0813981A

Other languages

English (en)

Inventor

Lakshmi Bhagat

Wnag Daqing

Yu Dong

R Kandimalla Ekambar

Mallikarjuna Reddy Putta

Agrawal Sudhir

Original Assignee

Idera Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-01

Filing date

2008-07-31

Publication date

2017-05-09

2008-07-31 Application filed by Idera Pharmaceuticals Inc filed Critical Idera Pharmaceuticals Inc

2017-05-09 Publication of BRPI0813981A2 publication Critical patent/BRPI0813981A2/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Neurology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Biochemistry (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Tropical Medicine & Parasitology (AREA)
Mycology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Virology (AREA)

BRPI0813981A 2007-08-01 2008-07-31 agonistas sintéticos da tlr9. BRPI0813981A2 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US95325107P	2007-08-01	2007-08-01
US98360107P	2007-10-30	2007-10-30
US98715107P	2007-11-12	2007-11-12
US1529207P	2007-12-20	2007-12-20
PCT/US2008/071738 WO2009018431A2 (en)	2007-08-01	2008-07-31	Novel synthetic agonists of tlr9

Publications (1)

Publication Number	Publication Date
BRPI0813981A2 true BRPI0813981A2 (pt)	2017-05-09

Family

ID=40305273

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0813981A BRPI0813981A2 (pt)	2007-08-01	2008-07-31	agonistas sintéticos da tlr9.

Country Status (12)

Country	Link
US (2)	US7960362B2 (pt)
EP (3)	EP2650369B1 (pt)
JP (2)	JP5563455B2 (pt)
KR (1)	KR20100053598A (pt)
CN (3)	CN102864151B (pt)
AU (1)	AU2008282172B2 (pt)
BR (1)	BRPI0813981A2 (pt)
CA (1)	CA2693266C (pt)
ES (2)	ES2539353T3 (pt)
IN (1)	IN2010KN00195A (pt)
RU (1)	RU2468819C2 (pt)
WO (1)	WO2009018431A2 (pt)

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US8158768B2 (en) *	2002-12-23	2012-04-17	Dynavax Technologies Corporation	Immunostimulatory sequence oligonucleotides and methods of using the same
US7354907B2 (en) *	2003-02-07	2008-04-08	Idera Pharmaceuticals, Inc.	Short immunomodulatory oligonucleotides
JP4874801B2 (ja) *	2003-06-11	2012-02-15	イデラファーマシューティカルズインコーポレイテッド	安定化免疫調節オリゴヌクレオチド
AU2004259204B2 (en) *	2003-07-15	2010-08-19	Idera Pharmaceuticals, Inc.	Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
JP4989225B2 (ja) *	2003-09-25	2012-08-01	コーリーファーマシューティカルグループ，インコーポレイテッド	核酸親油性接合体
CA2693266C (en) *	2007-08-01	2015-06-30	Idera Pharmaceuticals, Inc.	Novel synthetic agonists of tlr9
EP2391718A2 (en) *	2009-01-30	2011-12-07	Idera Pharmaceuticals, Inc.	Novel synthetic agonists of tlr9
CN102439153B (zh)	2009-03-25	2015-07-22	德克萨斯大学系统董事会	用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物
US8709419B2 (en)	2010-08-17	2014-04-29	Hoffmann-La Roche, Inc.	Combination therapy
US20120045433A1 (en) *	2010-08-17	2012-02-23	Kapil Dhingra	Combination therapy
US9295669B2 (en)	2010-12-14	2016-03-29	Hoffman La-Roche Inc.	Combination therapy for proliferative disorders
HK1214191A1 (zh) *	2013-01-08	2016-07-22	Idera Pharmaceuticals, Inc.	免疫調節寡核苷酸(iro)化合物以調節基於toll樣受體的免疫應答
AR095882A1 (es)	2013-04-22	2015-11-18	Hoffmann La Roche	Terapia de combinación de anticuerpos contra csf-1r humano con un agonista de tlr9
GB2514591A (en) *	2013-05-30	2014-12-03	Mologen Ag	Predictive biomarker for cancer therapy
PL3164113T3 (pl)	2014-06-04	2019-09-30	Exicure, Inc.	Wielowartościowe dostarczanie modulatorów immunologicznych w liposomowych kolistych kwasach nukleinowych do zastosowań profilaktycznych lub terapeutycznych
US20170298178A1 (en) *	2014-09-12	2017-10-19	Vantage Specialty Chemicals, Inc.	Derivatives of 1,3-propanediol
WO2016044839A2 (en)	2014-09-19	2016-03-24	The Board Of Regents Of The University Of Texas System	Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
IL251669B2 (en) *	2014-10-10	2023-02-01	Idera Pharmaceuticals Inc	Cancer treatment using a tlr9 agonist with checkpoint inhibitors
JP2017537619A (ja)	2014-11-21	2017-12-21	ノースウェスタンユニバーシティ	球状核酸ナノ粒子複合体の配列特異的細胞内取込
WO2017052403A1 (ru) *	2015-09-25	2017-03-30	Анатолий Викторович ЗАЗУЛЯ	Изготовление таблетки с механизмом повышения терапевтической эффективности лекарственного средства нанодозой микрорнк
WO2018039629A2 (en)	2016-08-25	2018-03-01	Northwestern University	Micellar spherical nucleic acids from thermoresponsive, traceless templates
AU2017325981A1 (en)	2016-09-15	2019-04-11	Idera Pharmaceuticals, Inc.	Immune modulation with TLR9 agonists for cancer treatment
EP4252629A3 (en)	2016-12-07	2023-12-27	Biora Therapeutics, Inc.	Gastrointestinal tract detection methods, devices and systems
EP3554344A1 (en)	2016-12-14	2019-10-23	Progenity, Inc.	Treatment of a disease of the gastrointestinal tract with a tlr modulator
WO2018209270A1 (en)	2017-05-11	2018-11-15	Northwestern University	Adoptive cell therapy using spherical nucleic acids (snas)
CN116813705A (zh)	2017-07-05	2023-09-29	凯惠科技发展(上海)有限公司	一种肽类化合物、其应用及含其的组合物
US11806364B2 (en)	2017-09-28	2023-11-07	Industry-Academic Cooperation Foundation, Yonsei University	Method for producing myeloid-derived suppressor cells, myeloid-derived suppressor cells produced thereby, and methods thereof
JP7622031B2 (ja)	2019-07-05	2025-01-27	タンボ・インコーポレイテッド	トランス－シクロオクテン生体直交型薬剤並びに癌及び免疫療法における使用
WO2021174024A1 (en)	2020-02-28	2021-09-02	First Wave Bio, Inc.	Methods of treating iatrogenic autoimmune colitis
WO2022003598A1 (en)	2020-07-02	2022-01-06	Viiv Healthcare Company	Method of achieving hiv viral remission using long-acting antiretroviral agents
CN116056765A (zh)	2020-08-07	2023-05-02	坦伯公司	反式环辛烯生物正交剂及在癌症和免疫疗法中的用途

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US7884197B2 (en) *	2006-12-12	2011-02-08	Idera Pharmaceuticals, Inc.	Synthetic agonists of TLR9
EP2209476A4 (en) *	2007-04-19	2011-01-19	Univ Pittsburgh	USE OF TOLL-LIKE RECEPTOR 9 AGONISTS; TOLL-LIKE RECEPTOR-4 ANTAGONISTS AND / OR NUCLEAR OLIGOMERIZATION DOMAIN-2-AGONSITES FOR TREATING OR PREVENTING DISEASES RELATED TO TOLL-LIKE RECEPTOR-4
CA2693266C (en) *	2007-08-01	2015-06-30	Idera Pharmaceuticals, Inc.	Novel synthetic agonists of tlr9

2008
- 2008-07-31 CA CA2693266A patent/CA2693266C/en active Active
- 2008-07-31 CN CN201210311690.3A patent/CN102864151B/zh not_active Expired - Fee Related
- 2008-07-31 US US12/183,439 patent/US7960362B2/en active Active
- 2008-07-31 JP JP2010520185A patent/JP5563455B2/ja active Active
- 2008-07-31 ES ES13171674.8T patent/ES2539353T3/es active Active
- 2008-07-31 EP EP20130171674 patent/EP2650369B1/en active Active
- 2008-07-31 AU AU2008282172A patent/AU2008282172B2/en active Active
- 2008-07-31 RU RU2010107207/10A patent/RU2468819C2/ru active
- 2008-07-31 EP EP14183548.8A patent/EP2821488B1/en active Active
- 2008-07-31 CN CN2008801098527A patent/CN101878311A/zh active Pending
- 2008-07-31 EP EP08796942A patent/EP2173912A4/en not_active Withdrawn
- 2008-07-31 ES ES14183548.8T patent/ES2585239T3/es active Active
- 2008-07-31 CN CN201510303003.7A patent/CN105177014B/zh not_active Expired - Fee Related
- 2008-07-31 KR KR1020107004710A patent/KR20100053598A/ko not_active Withdrawn
- 2008-07-31 BR BRPI0813981A patent/BRPI0813981A2/pt not_active IP Right Cessation
- 2008-07-31 WO PCT/US2008/071738 patent/WO2009018431A2/en active Application Filing
- 2008-07-31 IN IN195KON2010 patent/IN2010KN00195A/en unknown
2011
- 2011-06-08 US US13/156,140 patent/US8361986B2/en not_active Expired - Fee Related
2014
- 2014-06-11 JP JP2014120860A patent/JP5816720B2/ja active Active

Also Published As

Publication number	Publication date
RU2010107207A (ru)	2011-09-10
CN105177014B (zh)	2018-04-06
CN101878311A (zh)	2010-11-03
EP2173912A4 (en)	2013-03-20
CA2693266A1 (en)	2009-02-05
AU2008282172A1 (en)	2009-02-05
KR20100053598A (ko)	2010-05-20
HK1216430A1 (zh)	2016-11-11
EP2173912A2 (en)	2010-04-14
AU2008282172B2 (en)	2014-05-22
JP5563455B2 (ja)	2014-07-30
WO2009018431A3 (en)	2009-12-30
RU2468819C2 (ru)	2012-12-10
EP2821488A2 (en)	2015-01-07
ES2539353T3 (es)	2015-06-30
EP2650369B1 (en)	2015-04-29
WO2009018431A2 (en)	2009-02-05
ES2585239T3 (es)	2016-10-04
CN105177014A (zh)	2015-12-23
EP2821488A3 (en)	2015-04-29
CN102864151A (zh)	2013-01-09
JP5816720B2 (ja)	2015-11-18
CN102864151B (zh)	2015-07-08
EP2650369A1 (en)	2013-10-16
IN2010KN00195A (pt)	2015-08-28
US20090053206A1 (en)	2009-02-26
CA2693266C (en)	2015-06-30
JP2014205691A (ja)	2014-10-30
JP2010535242A (ja)	2010-11-18
EP2821488B1 (en)	2016-07-27
US20110311518A1 (en)	2011-12-22
US7960362B2 (en)	2011-06-14
US8361986B2 (en)	2013-01-29

Publication	Publication Date	Title
BRPI0813981A2 (pt)	2017-05-09	agonistas sintéticos da tlr9.
EP2261309A4 (en)	2013-01-09	LUBRICANT COMPOSITION
EP2319908A4 (en)	2014-12-17	LUBRICANT COMPOSITION
HRP20170963T1 (hr)	2017-09-22	Modificirani saharidi
FIC20240018I1 (fi)	2024-06-04	Vamoroloni
BRPI0807911A2 (pt)	2014-06-17	Agonistas de alfa2c adrenorreceptor
DE112009000964A5 (de)	2011-03-03	Tampon
EP2274525A4 (en)	2013-07-17	CAMP
DE112009005504A5 (de)	2013-05-02	Schmiermittelzusammensetzung
FI20086143A0 (fi)	2008-11-28	Pistorasia
BRPI0909287A2 (pt)	2015-08-11	Retenção
BRPI0908558A2 (pt)	2015-09-22	composição lubrificante
EP2248876A4 (en)	2011-10-12	LUBRICANT COMPOSITION
ITBO20070832A1 (it)	2009-06-20	Cotile
DE112009004416A5 (de)	2012-06-21	Kombinationsleuchte
BRPI0807853A2 (pt)	2014-06-24	Prendedor para vestuário.
IT1396642B1 (it)	2012-12-14	Statore.
FI8099U1 (fi)	2008-11-21	Vaarnalenkki
ITBS20080008A1 (it)	2009-07-23	Lampada
ITBS20080009A1 (it)	2009-07-23	Lampada
FR2946591B1 (fr)	2012-12-28	Sur-tapis eclairant.
EP2327379A4 (en)	2014-01-15	STENT
AT10397U3 (de)	2009-12-15	Leuchte
ES1066306Y (es)	2008-04-01	Pieza para corseteria
FI8123U1 (fi)	2008-12-15	Valaistu infotaulu

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2021-07-13	B350	Update of information on the portal [chapter 15.35 patent gazette]