[go: up one dir, main page]

BRPI0813823B8 - métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina - Google Patents

métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina

Info

Publication number
BRPI0813823B8
BRPI0813823B8 BRPI0813823A BRPI0813823A BRPI0813823B8 BR PI0813823 B8 BRPI0813823 B8 BR PI0813823B8 BR PI0813823 A BRPI0813823 A BR PI0813823A BR PI0813823 A BRPI0813823 A BR PI0813823A BR PI0813823 B8 BRPI0813823 B8 BR PI0813823B8
Authority
BR
Brazil
Prior art keywords
immunoglobulin
flow filtration
tangential flow
concentrating
producing
Prior art date
Application number
BRPI0813823A
Other languages
English (en)
Inventor
Rosenberg Eva
Winter Gerhard
Hepbildikler Stefan
Kuhne Wolfgang
Original Assignee
Hoffmann La Roche
Ludwig Maximilians Univ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38562282&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0813823(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche, Ludwig Maximilians Univ filed Critical Hoffmann La Roche
Publication of BRPI0813823A2 publication Critical patent/BRPI0813823A2/pt
Publication of BRPI0813823B1 publication Critical patent/BRPI0813823B1/pt
Publication of BRPI0813823B8 publication Critical patent/BRPI0813823B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

filtração de fluxo tangencial variável. a presente invenção refere-se a um método para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial no qual a pressão da transmembrana e o fluxo cruzado são variáveis.
BRPI0813823A 2007-07-17 2008-07-15 métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina BRPI0813823B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07013948.0 2007-07-17
EP07013948 2007-07-17
PCT/EP2008/005766 WO2009010269A1 (en) 2007-07-17 2008-07-15 Variable tangential flow filtration

Publications (3)

Publication Number Publication Date
BRPI0813823A2 BRPI0813823A2 (pt) 2015-01-06
BRPI0813823B1 BRPI0813823B1 (pt) 2018-08-07
BRPI0813823B8 true BRPI0813823B8 (pt) 2021-05-25

Family

ID=38562282

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0813823A BRPI0813823B8 (pt) 2007-07-17 2008-07-15 métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina

Country Status (14)

Country Link
US (1) US8633302B2 (pt)
EP (1) EP2170949B1 (pt)
JP (1) JP5432137B2 (pt)
KR (1) KR101215740B1 (pt)
CN (1) CN101754977B (pt)
AU (1) AU2008277886B8 (pt)
BR (1) BRPI0813823B8 (pt)
CA (1) CA2693443C (pt)
ES (1) ES2401820T3 (pt)
IL (1) IL203338A (pt)
MX (1) MX2010000534A (pt)
RU (1) RU2504549C2 (pt)
TW (1) TWI374051B (pt)
WO (1) WO2009010269A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2483304T1 (sl) * 2009-09-29 2016-08-31 F. Hoffmann-La Roche Ag Predfiltracijsko naravnavanje pufrskih snovi za močno koncentriran imunoglobulinski pripravek
LT2483305T (lt) * 2009-10-01 2016-11-25 F.Hoffmann-La Roche Ag Daugiakopis galutinis imunoglobulino filtravimas
EP2727643A1 (en) 2012-10-31 2014-05-07 Takeda GmbH Cross-flow ultrafiltration device and method for concentration of pharmaceutical compositions
US9439864B2 (en) * 2014-07-07 2016-09-13 Antriabio, Inc. Solvent extraction from biodegradable microparticles
GB201600287D0 (en) 2016-01-07 2016-02-24 Fujifilm Diosynth Biotechnologies Uk Ltd Process
WO2024012364A1 (en) * 2022-07-12 2024-01-18 Beigene Switzerland Gmbh Preparation methods for a highly concentrated pd1 antibody solution by ultrafiltration/diafiltration (uf/df)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256294A (en) 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus
GB9610992D0 (en) 1996-05-24 1996-07-31 Glaxo Group Ltd Concentrated antibody preparation
US6365395B1 (en) * 2000-11-03 2002-04-02 Millipore Corporation Process for removing protein aggregates and virus from a protein solution
US20060182740A1 (en) 2002-06-21 2006-08-17 Biogen Idec, Inc. Buffered formulations for concentrating antibodies and methods of use thereof
CN1226418C (zh) * 2002-07-12 2005-11-09 广东欧瑞卡生物工程有限公司 天然活性蛋白质和肽的分离纯化方法
AU2003261387A1 (en) * 2003-02-24 2004-09-17 Gtc Biotherapeutics, Inc. Methods of tangential flow filtration and an apparatus therefore
AR045614A1 (es) 2003-09-10 2005-11-02 Hoffmann La Roche Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
US20050197496A1 (en) 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
EP2374817B1 (en) 2004-04-13 2017-09-06 F. Hoffmann-La Roche AG Anti-P-selectin antibodies
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
TW200640443A (en) 2005-02-23 2006-12-01 Alcon Inc Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors

Also Published As

Publication number Publication date
JP2010533663A (ja) 2010-10-28
CN101754977A (zh) 2010-06-23
TWI374051B (en) 2012-10-11
AU2008277886A1 (en) 2009-01-22
RU2504549C2 (ru) 2014-01-20
EP2170949B1 (en) 2012-12-26
BRPI0813823A2 (pt) 2015-01-06
EP2170949A1 (en) 2010-04-07
TW200914120A (en) 2009-04-01
CA2693443C (en) 2018-02-13
KR101215740B1 (ko) 2012-12-27
US20100196961A1 (en) 2010-08-05
RU2010105311A (ru) 2011-08-27
KR20100049066A (ko) 2010-05-11
MX2010000534A (es) 2010-04-22
WO2009010269A1 (en) 2009-01-22
IL203338A (en) 2014-03-31
ES2401820T3 (es) 2013-04-24
CA2693443A1 (en) 2009-01-22
CN101754977B (zh) 2013-07-17
BRPI0813823B1 (pt) 2018-08-07
US8633302B2 (en) 2014-01-21
AU2008277886B8 (en) 2013-08-01
JP5432137B2 (ja) 2014-03-05
AU2008277886B2 (en) 2013-03-14

Similar Documents

Publication Publication Date Title
EP2239043A4 (en) SEPARATE MEMBRANE ELEMENTS, SEPARATE MEMBRANE MODULE AND METHOD FOR PRODUCING A SEPARATE MEMBRANE ELEMENT
BRPI0813823B8 (pt) métodos para concentração de uma solução de imunoglobulina por filtração de fluxo tangencial, e para produção de uma imunoglobulina
BRPI0914702A2 (pt) processo para a preparação de uma membrana de permeabilidade seletiva, membrana com nanotubos embutidos, e, método para dessalinização de água.
WO2006089540A3 (de) Verfahren zur herstellung eines optischen und eines strahlungsemittierenden bauelementes und optisches sowie strahlunsemittierendes bauelement
BRPI0919083A2 (pt) processo para preparação de uma membrana, e, membrana assimétrica.
NL1026467A1 (nl) Composiet semipermeabel membraan, alsmede productiewerkwijze daarvoor.
DK1869171T3 (da) Virusrensning under anvendelse af ultrafiltrering
MX350375B (es) Moleculas de union especificas de virus sincitial respiratorio y medios para producirlas.
BR112012001481B8 (pt) Membranas de poli-imida, e seu processo de preparação
MA32484B1 (fr) Procedes de separation par osmose directe
BRPI0818374A8 (pt) Substratos porosos hidrofílicos
BRPI0807756A2 (pt) Método para produzir um l-aminoácido.
EA201100727A1 (ru) Новый способ получения производных аминокислот
EA201001062A1 (ru) Мембрана из полых волокон
DK2291329T3 (da) Apparatur til rensning af væsker, især ballastvand
EP2927282A4 (en) POLYMER RESIN COMPOSITION FOR PRODUCING A MICROFILTRATION MEMBRANE OR AN ULTRASTRIBRARY MEMBRANE, PRODUCTION PROCESS FOR THE POLYMER FILTRATION MEMBRANE AND POLYMER FILTRATION MEMBRANE
WO2009114438A3 (en) Cyclohexanedimethanamine by direct amination of cyclohexanedimethanol
WO2010132604A3 (en) Neutralizing molecules to influenza viruses
BRPI0816429A2 (pt) microorganismo, e, método para a produção de um l-aminoácido.
EP2236575A4 (en) METHOD FOR BONDING A RESIN BY IRRADIATION OF EXTREME ULTRAVIOLET RADIATION, METHOD FOR MANUFACTURING RESIN ARTICLE OR RESIN MICROCHIP USING THE METHOD, AND RESIN ARTICLE OR MICROCHIP OBTAINED BY THE METHOD
SG11202012263QA (en) Fouling resistance reverse osmosis membrane, method for producing same, and fouling resistance reverse osmosis module including same
DK2365961T3 (da) Fremgangsmåde til fremstilling af cykliske diaminer
EP2394679A4 (en) HOLLOW FIBER MEMBRANE, PROCESS FOR PRODUCING THE SAME, AND BLOOD PURIFICATION MODULE
EP2698830A4 (en) RESIN FOIL FOR SEALING SOLAR CELLS, SOLAR CELL MODULE THEREWITH AND METHOD FOR PRODUCING A SOLAR CELL MODULE
EP3290103A4 (en) Polymer functional film, method for producing same, composition for forming polymer functional film, separation membrane module and ion exchange device

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/07/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF